Articles tagged "Age factors"

2016 American Transplant Congress
Pediatric En Bloc Kidney Transplants Reduce DGF and Are Misrepresented by the KDPI.
M. Khan,¹ H. El-Hennawy,¹ A. Farney,¹ J. Rogers,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² M. Gautreaux,³ S. Iskandar,³ W. Doares,⁴ S. Kaczmorski,⁴ R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC; ³Pathology, Wake Forest, Winston-Salem, NC; ⁴Pharmacy, Wake Forest, Winston-Salem, NC.
Controversy exists regarding optimal use of kidneys from small pediatric donors (SPDs). The study purpose was to compare outcomes between single and dual en bloc…
2016 American Transplant Congress
Young Recipients Receiving Kidneys from Older Donors Have Poorer Allograft Outcomes.
A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Introduction: An increasing number of marginal donors are being used in order to expand the donor pool. Age is one of the major criteria in…
2016 American Transplant Congress
15-Years Experience with the EUROTRANSPLANT Senior Program.
H.-M. Tautenhahn,¹ S. Brückner,¹ H.-M. Hau,¹ H. Morgül,¹ J. Broschewitz,¹ C. Pipiale,¹ F. Pankow,¹ S. Erler,² M. Bartels.¹
¹Universitätsklinikum Leipzig, Leipzig, Germany; ²Martin-Luther-Universität Halle, Halle, Germany.
Introduction: The ESP (Eurotransplant senior program), introduced in 1999 by EUROTRANSPLANT, is supposed to shorten the waiting period for elder recipients. The aim of this…
2016 American Transplant Congress
Replicative Senescence and Arteriosclerosis After Kidney Transplantation.
K. De Vusser,¹ D. Martens,² E. Lerut,³ D. Kuypers,¹ T. Nawrot,² M. Naesens.¹
¹Department of Nephrology and Renal Transplantation, UZ Leuven, Leuven, Belgium; ²Department of Imaging and Pathology, KULeuven, Leuven, Belgium; ³Centre for Environmental Sciences, U Hasselt, Hasselt, Belgium.
BackgroundReplicative senescence is associated with telomere shortening. In native kidneys, obtained prior to transplantation, we recently described and validated a significant association between shorter intrarenal…
2016 American Transplant Congress
Defining Frailty in Liver Transplant Recipients.
L. Louwers,¹ K. Eid,¹ J. Plescia,¹ N. Presser,¹ J. Muntean,¹ M. Kattan,² K. Chagrin,² C. Miller,¹ D. Kelly.¹
¹Surgery, Cleveland Clinic, Cleveland, OH; ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
PURPOSETo define frailty in the liver transplant (OLT) population to optimize care and assist in predicting post OLT outcomes.METHODSAll adult primary OLT patients from 01/2010…
2016 American Transplant Congress
Induction Agent Use and Outcomes in Older KT Recipients: Patient and Center Level Associations.
M. McAdams-DeMarco, Q. Huang, X. Luo, B. Orandi, S. Dorry.
Johns Hopkins, Baltimore.
Background: Clinical trials of induction agents typically exclude older recipients, so our practice in older recipients is extrapolated from this. Older adults are different, so…
2016 American Transplant Congress
C1-Inhibitor Abrogated Ischemia/Reperfusion (I/R) Induced Inflammaging by Inhibiting Senescence-Associated Secretory Phenotype (SASP) in Tubular Epithelial Cells (TEC).
G. Castellano,¹ R. Franzin,¹ A. Stasi,¹ C. Divella,¹ M. Gigante,¹ S. Simone,¹ A. Intini,¹ A. Picerno,¹ P. Pontrelli,¹ A. Crovace,¹ M. Battaglia,¹ B. Oortwijn,² E. Amersfoort,² G. Grandaliano,³ L. Gesualdo.¹
¹Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy; ²Pharming Technologies, Leiden, Netherlands; ³Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Inflammaging is a pathogenic process usually associated with chronic kidney disease such as diabetic nephropathy where TEC cells have a diminished regenerative potential and develop…
2016 American Transplant Congress
The Effect of Families on Organ Donation Among Native Americans.
T. Bongiovanni,^1,3 J. Rawlings,² J. Trompeta.¹
¹Dept of Surgery, UCSF, San Francisco, CA; ²CT Native American Tribal Council, New Haven, CT; ³Robert Wood Johnson Foundation CSP, Yale University School of Medicine, New Haven, CT.
Background: Prevalence of end-stage renal disease is 3.5 times greater among the >2.5 million Native Americans (NAs) in the US than in Caucasians, due to…
2015 American Transplant Congress
Age-Specific Graft Failure Rates in Pediatric Heart Transplant Recipients
B. Foster,¹ M. Dahhou,¹ X. Zhang,¹ V. Dharnidharka,² V. Ng,³ J. Conway.⁴
¹Pediatrics, Research Institute of the McGill Univ. Health Centre, Montreal, QC, Canada; ²Pediatrics, Washington Univ., St. Louis, MO; ³Pediatrics, Hospital for Sick Children, Toronto, ON, Canada; ⁴Pediatrics, Stollery Children's Hospital, Edmonton, AB, Canada.
Graft failure risk has been shown to peak during emerging adulthood (18-25 y) among kidney transplant recipients. The association between age and graft failure risk…
2015 American Transplant Congress
Renal Cell Carcinoma in the Native Kidney in Dialysis and Kidney Transplantation Recipients. Different Entities?
K. Yamaçake, W. Nahas, H. Kanashiro, R. Kato, A. Bull, I. Antonopoulos, R. Falci, A. Piovesan.
Division of Urology, Renal Transplantation Unit, University of São Paulo, São Paulo, SP, Brazil.
Purpose: Renal Cell Carcinoma (RCC) has a high incidence in patients with acquired cystic kidney disease (ACKD) due to hemodialysis. It has been reported that…