Articles tagged "Age factors"

2017 American Transplant Congress
Outcome of Kidney Transplantation from Deceased Octogenarian Donors.
P. Donato, L. Furian, C. Silvestre, F. Neri, C. Di Bella, M. Di Bello, P. Rigotti.
Kidney and Pancreas Transplantation Uniti, Padua University Hospital, Padua, Italy
In order to expand the donor pool, the utilization of kidneys otherwise discarded because of extremely old age or comorbidities has been evaluated.We retrospectively analyzed…
2017 American Transplant Congress
The New Kidney Allocation System: The Effect on Elderly Transplantation in the US. Review of UNOS Database.
V. Whittaker, M. Laftavi, Z. Acun, R. Gruessner, A. Gruessner.
Surgery, State University New York, Syracuse, NY
The New Kidney Allocation System(KAS) improve access disadvantaged groups. The effect on the elderly population, recipients >=65 is unknown.Methods: Retrospective analysis of UNOS database preKAS…
2017 American Transplant Congress
Charlson Comorbidity Index (CCI) as Prognostic Indicator of Outcomes in Older Patients Undergoing Renal Transplantation.
A. Asderakis, U. Contractor, U. Khalid, P. Donato, L. Szabo.
Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom
Introduction: Our group has shown excellent results using old DCD donor kidneys to older recipients. There are continuing efforts to predict those older recipients who…
2017 American Transplant Congress
Pre-Kidney Transplant Lower Extremity Impairment and Post-Transplant Mortality.
A. Nastasi,^1,2 M. McAdams-DeMarco,^1,2 J. Schrack,¹ H. Ying,² C. Haugen,² M. González Fernández,³ D. Segev.^1,2
¹Epidemiology, Johns Hopkins University, Baltimore, MD; ²Surgery, Johns Hopkins University, Baltimore, MD; ³Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD
INTRODUCTION. Few objective tests can be easily performed prior to kidney transplantation (KT) to effectively stratify patients by risk of post-KT mortality. The short physical…
2017 American Transplant Congress
Tacrolimus Suppresses Calcineurin Activity and Ca2+ Influx Age-Specifically.
F. Krenzien,^1,2 M. Quante,¹ H. Uehara,¹ R. Abdi,¹ H. Cetina Biefer,¹ M. Schmelzle,² J. Pratschke,² A. Elkhal,¹ S. Tullius.¹
¹Transplant Surgery Research Laboratory and Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston; ²Department of Surgery, Campus Virchow-Klinikum and Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany
Immunosenescence is impacting alloimmunity and outcomes after organ transplantation. Age-dependent effects of immunosuppressants, however, have not been tested sufficiently. Here, we tested the effects of…
2017 American Transplant Congress
Non-Directed Donors (NDD) Less Than 25 Years.
D. Larson, J. Wiseman, A. Roman, D. Berglund, H. Ibrahim, A. Matas.
UofM, Mpls
Many transplant centers will not accept NDDs less than 25 because of: a) concerns about maturity; and b) they potentially have decades during which they…
2017 American Transplant Congress
Age and Gender Disparities in Post-Lung Transplant Mortality.
H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.
JHU, Baltimore
Gender, race, and age have been associated with health disparities, including in post-transplant outcomes. Given disparities in post-lung transplant outcomes are not well-understood, we assess…
2016 American Transplant Congress
End Stage Renal Disease Patients Have a Skewed T Cell Receptor Vbeta Repertoire.
L. Huang,¹ A. Langerak,² I. Wolvers - Tettero,² R. Meijers,¹ C. Baan,¹ N. Litjens,¹ M. Betjes.¹
¹Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; ²Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
IntroductionEnd stage renal disease (ESRD) is associated with a defective T-cell mediated immunity, resembling premature T-cell ageing. A diverse T-cell receptor Vbeta (TCR Vβ) repertoire…
2016 American Transplant Congress
Ageing as a Barrier to Transplant Tolerance.
J. Kim, R. Stott, H. Deirawan, L. Kojima, L. Washburn, G. Zhao, H. Yeh, J. Markmann.
Surgery/Transplant, Massachusetts General Hospital, Harvard Medical, Boston, MA.
We recently demonstrated that ageing also impedes development of transplantation tolerance. Unlike their young counterparts (8-12 weeks of age) aged male recipients (greater than 12…
2016 American Transplant Congress
Impact of Social Support on Feelings of Powerlessness and Attitudes Towards the Kidney Transplant in Long-Term Inner City Recipients.
S. Wu, A. Brar, M. Markell.
Medicine, SUNY Downstate Medical Center, Brooklyn, NY.
Psychosocial factors play an important role in the post-transplant period, affecting adherence and quality of life. We investigated the relationships between social support, attitude towards…