2017 American Transplant Congress
Tacrolimus Suppresses Calcineurin Activity and Ca2+ Influx Age-Specifically.
Immunosenescence is impacting alloimmunity and outcomes after organ transplantation. Age-dependent effects of immunosuppressants, however, have not been tested sufficiently. Here, we tested the effects of…2017 American Transplant Congress
Non-Directed Donors (NDD) Less Than 25 Years.
Many transplant centers will not accept NDDs less than 25 because of: a) concerns about maturity; and b) they potentially have decades during which they…2017 American Transplant Congress
Age and Gender Disparities in Post-Lung Transplant Mortality.
Gender, race, and age have been associated with health disparities, including in post-transplant outcomes. Given disparities in post-lung transplant outcomes are not well-understood, we assess…2017 American Transplant Congress
Age and Race Disparities Among Pediatric and Adult Cystic Fibrosis Lung Transplant Recipients.
Pediatric cystic fibrosis (CF) patients have a post-lung transplant survival disadvantage compared to adults. However, whether race and age are risk factors associated with post-transplant…2017 American Transplant Congress
Propensity-Score Matched Comparison of Lung Transplant Recipients of Age <70 and ≥70 Years.
Purpose: To validate the utilization of lung transplantation (LTx) recently in older recipients, we compared the survival outcome of the LTx recipients of age <70…2017 American Transplant Congress
Accelerated Rejection of Secondary Third Party Allografts in Older Recipients Is Facilitated by an Augmented Innate Immune Response.
Accumulating evidence acknowledges the central relevance of aging and chronic antigen exposure in shaping the balance of innate and adaptive immunity. Here, we assessed whether…2017 American Transplant Congress
Utility of a 10-Minute Functional Test as a Predictor of Kidney Transplant (KTP) Listing.
Purpose: Frailty is a measure of physiologic reserve that has been associated with poor outcomes after kidney transplant, but its use as a predictor for…2017 American Transplant Congress
Organs with Extended Cold Ischemia Time May Offer Aged Kidney Transplant Recipients New Options in an Expanded Donor Pool.
Using data from the largest cohort of renal transplants, the aim of this study was to examine the effects of cold ischemia times (CIT) on…2017 American Transplant Congress
Kidney Transplantation in Octogenarians: The Mayo Clinic Experience.
Transplant Center, Mayo Clinic, Rochester, MN
BackgroundKidney transplantation (KTx) is the preferred renal replacement therapy in selected individuals.There is limited data on transplantation of octogenarians. The purpose of this study was…2017 American Transplant Congress
Young African American Heart Transplant Recipients Have an Elevated Risk of Post-Transplant Mortality.
African American (AA) race is associated with worse survival among heart transplant recipients. Even after controlling for socioeconomic and clinical characteristics, racial disparities persist and…
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