Articles tagged "Age factors"

2018 American Transplant Congress
The Continuous Debate of Older Donors into Older Recipients: Another Angle
J. Patel, M. Kittleson, E. Kransdorf, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Heart transplantation (HTx) remains limited by donor availability. Many programs accept older donors (≥50 yrs) for older recipients (≥ 60 yrs) in an effort…
2018 American Transplant Congress
Risk Factors and Sequelae of Post-KT Delirium
M. McAdams DeMarco, A. Mountford, F. Warsame, R. Berkowitz, H. Ying, C. Haugen, D. Brennan, D. Segev.
JHU, Baltimore.
Background: Delirium is the acute decline in cognitive function following a noxious insult like surgery. Previous studies in other surgical settings have identified frailty and…
2018 American Transplant Congress
Increased Length of Stay of the Donor Decreases Heart Transplant Recipient Survival
H. Copeland,¹ R. Talluri,² A. Panos,¹ R. Cochran,¹ L. Creswell,¹ D. Baran.³
¹Surgery, University of Mississippi Medical Center, Jackson, MS; ²Biostatistics, University of Mississippi Medical Center, Jackson, MS; ³Cardiology, Sentara Heart Hospital, Norfolk, VA.
Purpose: We hypothesize that the longer the cardiac donor is in the hospital prior to procurement, the worse the heart transplant (tx) recipient outcome for…
2018 American Transplant Congress
Recipient Outcomes in Age Mismatched Living Kidney Transplants from Donors > 60 Years: A UNOS Database Analysis
O. Adebiyi, A. Riaz, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Background: Donor and recipient age mismatch kidney transplantation are known to affect graft survival. We examined the impact of age mismatching on graft survival after…
2018 American Transplant Congress
The Impact of Age-Matching on Graft Function and Graft Survival after Living Donor Kidney Transplantation
J. Lee,¹ D. Kim,¹ J. Lee,¹ J. Lee,¹ Y. Jung,¹ M. Ju,¹ S. Song,² J. Lee,³ K. Huh,¹ B. Kim,⁴ S. Kim,¹ Y. Kim,¹ M. Kim.¹
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, Ewha Womans University, School of Medicine, Seoul, Republic of Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea; ⁴Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Introduction: To overcome the shortage of organs, the influence of age matching in living donor kidney transplantation should be studied. We analyzed the impact of…
2018 American Transplant Congress
Two Decades of Eurotransplant Senior Program (ESP): Time on Dialysis Independently Impacts Patient Survival, Allograft Survival and Quality of Life after Kidney Transplantation
T. Schachtner,^1,2,3 N. Otto,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charite Campus Virchow Clinic, Berlin, Germany; ³Berlin Institute of Health (BIH), Charite and Max Delbrueck Center, Berlin, Germany.
In 1999, the Eurotransplant Senior Program (ESP) was implemented and allocates kidneys from deceased-donors ≥65 years to kidney transplant recipients ≥65 years (ESP-KTRs). The ESP…
2018 American Transplant Congress
Multivariate Cox Proportional Hazards Model for Estimating Long-Term Risk of Aging Kidney Transplant Recipients
A. Yaldo, I. Bajjoka, X. Han, C. Crombez, M. Abouljoud.
Henry Ford Transplant Institute, Detroit, MI.
Purpose: The growing number of elderly kidney transplant recipients (KTR) presents an opportunity to analyze and predict long-term outcomes and risk in this aging population.Methods:…
2018 American Transplant Congress
Senolytic Drug Treatment Attenuates mtDNA-Mediated Inflammatory Injury in Old Donors and Prolongs Cardiac Allograft Survival
K. Minami,¹ M. Seyda,¹ T. Heinbokel,¹ Y. Nian,¹ M. Quante,¹ G. Liu,¹ R. Abdi,² T. Tchkonia,³ J. Kirkland,³ A. Elkhal,¹ S. Tullius.¹
¹Transplant Surgery Division, Department of Surgery, Brigham and Women's Hospital, Boston, MA; ²Transplantation Research Center, Brigham and Women's Hospital, Boston; ³Robert and Arlene Kogod Center on Aging, Mayo Clinic College of Medicine, Rochester, MN.
Introduction: Solid organ transplantation has seen a increase in the utilization of older organs. Here, we investigate how aging-associated kinetics of damage associated molecular patterns…
2018 American Transplant Congress
Exploring the Impact of Recipient Age with Kidney Donor Risk Index and Estimated Glomerular Filtration Rate at One Year Following Kidney Transplant
S. Chan,^1,2,3 M. Chatfield,⁴ K. Baboolal.^2,3
¹Australian and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia; ²Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; ³Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia; ⁴Statistics Unit, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.
Background: Various kidney donor risk indexes (KDRI) have been developed to predict graft survival with various combinations of donor and recipient characteristics. The aim of…
2018 American Transplant Congress
Liver Transplants from Older Donors Have Worse Outcomes in Elderly Recipients with Renal Dysfunction
R. Schilke,¹ M. Safwan,¹ S. Nagai,¹ M. Abouljoud,² A. Patel.¹
¹Transplant Institute, Henry Ford Health System, Detroit, MI; ²Nephrology, Henry Ford Health System, Detroit, MI.
Background: Most end stage liver disease patients suffer from concomitant renal insufficiency. We aimed to study influence of donor age on outcomes in elderly liver…