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Articles tagged "African-American"

  • 2015 American Transplant Congress

    African American Race Is an Independent Risk Factor for Cytomegalovirus Infection in Renal Transplant Recipients on Low-Dose Valganciclovir Prophylaxis

    S. Patel, S. Kuten, J. Loucks-DeVos, R. Knight, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Safe and effective use of low-dose (450 mg/day) valganciclovir (VGC) for cytomegalovirus (CMV) prophylaxis in renal transplant recipients (RTRs) has been reported. However, it is…
  • 2015 American Transplant Congress

    Effect of Antibody Mediated Rejection on Long-Term Renal Allograft Function

    M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Historically we had poor understanding of chronic rejection attributing it to hypertension and non-compliance. However in the last decade we have begun to understand the…
  • 2015 American Transplant Congress

    Effect of 2007 CMS Conditions of Participation on High Risk Renal Transplantation: A Study of the United States Renal Data System

    D. John, A. Brar, F. Tedla, N. Sumrani, E. Timpo, M. Salifu.

    Division of Transplantation, SUNY Downstate Medical Center, Brooklyn, NY.

    BACKGROUND: On June 28, 2007, CMS introduced new Conditions of Participation (CoP) for Transplant Centers- the impact of these regulations on adult patients at high…
  • 2015 American Transplant Congress

    Efficacy, Safety and Pharmacokinetics of Once-Daily, MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus (Prograf®) in De Novo Kidney Transplant Recipient Sub-Groups: A 2 Year Phase 3 Randomized, Double-Blind, Double-Dummy, Trial

    S. Bunnapradist,1 J. Denny,2 M. Waybill,3 P. West-Thielke,4 S. Steinberg.5

    1David Geffen School of Medicine at UCLA, Los Angeles; 2Henry Ford Hospital, Detroit; 3Central Pennsylvania Transplant Foundation, Harrisburg; 4University of Illinois at Chicago, Chicago; 5California Institute of Renal Research, San Diego.

    Differences in tacrolimus (tac) metabolism are evident in certain populations; in particular, lower tac bioavailability has been shown in females and black kidney transplant recipients…
  • 2015 American Transplant Congress

    Correlates and Consequences of Gout Among Living Kidney Donors

    N. Lam,1 A. Garg,1 D. Segev,2 M. Schnitzler,3 H. Xiao,3 D. Axelrod,4 J. Tuttle-Newhall,3 D. Brennan,5 B. Kasiske,6 K. Lentine.3

    1Western Uni., London, Canada; 2John Hopkins Uni., Baltimore; 3Saint Louis Uni., St. Louis; 4Dartmouth Hitchcock Medical Center, Hanover; 5Washington Uni., St. Louis; 6Uni. of Minnesota, Minneapolis.

    Background: Currently, the demographic correlates and consequences of gout in living kidney donors are understudied.Methods: We examined a novel database that linked national U.S. identifiers…
  • 2015 American Transplant Congress

    Identification of Genetic Variants Associated With Variation of Tacrolimus Levels in African Americans Using GWAS

    W. Oetting,1 D. Schladt,2 W. Guan,1 A. Israni,2 R. Remmel,1 C. Dorr,2 K. Sanghavi,1 R. Mannon,3 B. Herrera,4 A. Matas,1 D. Salomon,5 P. Kwok,4 P. Jacobson,1 for DeKAF Genomics.1

    1Univ. of Minnesota, Minneapolis; 2Minneapolis Medical Research Foundation, Minneapolis; 3Univ. of Alabama, Birmingham; 4Univ. of California, San Francisco; 5Scripps Research Center, La Jolla.

    African American kidney transplant recipients (AA) have a higher incidence of allograft failure when compared to Caucasians. We have previously reported that tacrolimus troughs (TT)…
  • 2015 American Transplant Congress

    Campath Induction With Triple Maintenance Therapy in African American Kidney Transplant Recipients: Less Infections But Worse Graft Survival

    M. Gillespie, F. Rasetto, B. Masters, T. Sparkes, B. Ravichandran, M. Moss, A. Haririan.

    University of Maryland Medical Center, Baltimore, MD.

    Introduction:African American (AA) kidney transplant recipients (KTR) are at a higher risk for worse clinical outcomes vs non-AA. Strategies to improve outcomes in AA KTR…
  • 2015 American Transplant Congress

    APOL1 High-Risk Genotype in African American Live Kidney Donors Is Not Associated With Post-Donation Development of Hypertension and Kidney Disease

    M. Doshi,1 M. Goggines,2 C. Winkler,3 J. Kopp.4

    1Wayne State University, Detroit, MI; 2Henry Ford Transplant Institute, Detroit, MI; 3NCI and Leidos, Frederick, MD; 4NIDDK, Bethseda, MD.

    African Americans (AA) with two apolipoprotein L1 (APOL1) risk alleles have more kidney disease than compared to those with one or zero risk alleles. A…
  • 2015 American Transplant Congress

    Controlling for Socioeconomic Barriers Reduces Racial Disparities in Transplant Pursuit

    A. Waterman,1 J. Peipert,1 C. Kynard-Amerson,1 A.-M. McSorley,1 A. Paiva,2 M. Robbins,2 L. Peace.3

    1David Geffen School of Medicine, UCLA, Los Angeles, CA; 2University of Rhode Island, Kingston, RI; 3Missouri Kidney Program, Columbia, MO.

    Compared to White dialysis patients, Black patients experience more socioeconomic barriers (SEBs) including higher financial insecurity and worse health insurance. To examine how SEBs affect…
  • 2015 American Transplant Congress

    Socioeconomic Determinants of Racial Disparities in Access to Preemptive Live Donor Kidney Transplantation

    T. Purnell, X. Luo, A. Massie, D. Crews, L. Cooper, D. Segev.

    Johns Hopkins, Baltimore.

    Racial/ethnic minorities have less access to preemptive live donor kidney transplantation (PLDKT) than whites. Our objective was to examine determinants of racial/ethnic disparities in PLDKTs…
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