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Articles tagged "Adverse effects"

  • 2016 American Transplant Congress

    Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.

    S. Yeager, A. Carlson, C. Truax, N. Kenyon, F. Ahmed, J. Corbett, F. Shihab, L. Smith.

    University of Utah Health Care, Salt Lake City, UT.

    Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…
  • 2016 American Transplant Congress

    Relationship Between Clinical Events and Everolimus Exposure at 12 Months in De Novo Renal Transplant Recipients.

    F. Shihab,1 Y. Qazi,2 S. Mulgaonkar,3 K. McCague,4 D. Patel,4 V. Peddi,5 D. Shaffer.6

    1University of Utah, Salt Lake City, UT; 2University of Southern California, Los Angeles, CA; 3Barnabas Health, West Orange, NJ; 4Novartis Pharmaceuticals Corporation, East Hannover, NJ; 5California Pacific Medical Center, San Francisco, CA; 6Vanderbilt University, Nashville, TN.

    We assessed the incidence of post-transplant biopsy-proven acute rejection (BPAR), graft loss and other adverse events (AEs) associated with everolimus (EVR) and tacrolimus (TAC) exposure…
  • 2016 American Transplant Congress

    In Their Own Words: Living Kidney Donors Who Develop Kidney Failure.

    L. Ross,1 C. Halverson,2 J. Wang,1 M. Poulson,3 J. Karlin,4 M. Crowley-Matoka.5

    1U Chicago, Chicago, IL; 2Anthropology, U Chicago, Chicago, IL; 3Georgetown U, Washington, DC; 4Family Medicine, UCSF, San Francisco, CA; 5Medical Humanities, Northwestern U, Chicago, IL.

    Background: Psychosocial data about living kidney donation have been collected for almost five decades. The results are almost uniformly positive, even in the early years…
  • 2016 American Transplant Congress

    Everolimus versus Mycophenolate Mofetil in Combination with Tacrolimus: A Propensity Score Matching Analysis in Liver Transplantation.

    P. de Simone,1 P. Carrai,1 A. Precisi,2 L. Coletti,1 D. Ghinolfi,1 F. Filipponi.1

    1Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospitals, Pisa, Italy; 2Laboratory, University of Pisa Medical School Hospital, Pisa, Italy.

    Background: No trial has so far investigated everolimus (EVR)-incorporating immunosuppressive regimens versus combined use of tacrolimus (TAC) and mycophenolate mofetil (MMF) in liver transplantation (LT).Materials…
  • 2016 American Transplant Congress

    Pre-Transplant Intra-Arterial Liver Directed Therapy Does Not Increase the Risk of Hepatic Arterial Misadventures in Liver Transplantation.

    J. Kallini,2 A. Gabr,2 R. Salem,2 R. Lewandowski,2 T. Baker.1

    1Comprehensive Transplant Center, Northwestern University, Chicago, IL; 2Division of Interventional Oncology, Northwestern University, Chicago, IL.

    Background: Pretransplant liver directed therapy has emerged as standard of care for patients with end stage liver disease complicated by unresectable hepatocellular cancer. The aim…
  • 2016 American Transplant Congress

    Earlier Repletion of Lymphocytes After Alemtuzumab Induction Is Associated with a Lower Incidence of Infection Following Renal Transplantation.

    M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Alemtuzumab has been increasingly used as an induction agent in renal transplantation, although the optimal dose is unknown. We have previously reported that alemtuzumab…
  • 2016 American Transplant Congress

    Chemoprevention of Cutaneous Squamous Cell Carcinoma in Renal Transplant Recipients: A Case-Controlled Analysis.

    R. Anand, R. Hung, S. Frame, K. Bramham, M. Wain, A. Cronin.

    Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

    Organ transplant recipients are up to 200 times more likely to develop cutaneous squamous cell carcinoma (SCC) than age-matched general populations. Systemic retinoids, such as…
  • 2016 American Transplant Congress

    A Novel Inflammation-Targeting Tacrolimus Hydrogel for Liver Transplantation.

    J. Jia,1 J. Li,12 Y. Zhou,1 L. Jiang,1 J. Zhang,1 H. Lu,1 H. Xie,1 L. Zhou,1 P. Kumur,3 S. Zheng.12

    1Key Laboratory of Combined Multiorgan Transplantation, Ministry of Public Health, Hangzhou, China; 2Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; 3Division of Biomedical Engineering and Department of Medicine, Brigham and Women's Hospital, Boston.

    Background:Immunosuppressant have played a critical role for improving graft survival after liver transplantation (LT). While long-term systemic use of immunosuppressant such as tacrolimus (FK506) is…
  • 2016 American Transplant Congress

    A Prospective Randomized, Comparative Trial of High-Dose Mizoribine versus Mycophenolate Mofetil in Combination with Tacrolimus and Basiliximab for Living Donor Renal Transplantation: A Multi-Center Trial.

    H. Ishida,1 K. Tanabe,1 S. Takahara,2 N. Amada,3 K. Takahashi,4 H. Toma.5

    1Urology, Tokyo Women's Medical University Hospital, Tokyo, Japan; 2Advanced Technology for Transplantation, Osaka University, Osaka, Japan; 3Surgery, JCHO Sendai Hospital, Sendai, Japan; 4Niigata Organ Transplant Foundation, Niigata, Japan; 5Urology, Toda Chuo Hospital, Toda, Saitama, Japan.

    PURPOSE: To compare the clinical outcomes of mizoribine (MZR; 12 mg/kg/day) and mycophenolate mofetil (MMF; 2000 mg/day) in combination with tacrolimus (FK), basiliximab (SIM), and…
  • 2016 American Transplant Congress

    Telemedicine to Reduce Readmissions Post Liver Transplant: Compliance and Feasibility Results.

    T. Kaiser,1 P. Kimmel,2 S. Osborn,2 S. Diersing,2 B. Boswell,2 J. Huff,2 J. Garrett,1 N. Anwar,1 S. Shah.1

    1Medicine, University of Cincinnati, Cincinnati, OH; 2Transplant, University of Cincinnati Medical Center, Cincinnati, OH.

    Telemedicine (TM) was added to our care model as a mechanism to reduce readmissions post liver transplant (LTx). Establishing a TM home allows for remote…
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