ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Adverse effects"

  • 2016 American Transplant Congress

    Evaluation of the Toxicity Profile of Proteasome Inhibitor-Based Therapy for Antibody Mediated Rejection.

    A. Leino,1 A. Lichvar,1 B. Abu-Jawdeh,1 A. Govil,1 G. Mogilishetty,1 M. Cardi,2 J. Kremer,2 M. Cuffy,1 F. Paterno,1 R. Alloway,1 A. Shields,1,2 E. Woodle.1

    1U of Cinncinati, Cincinnati; 2The Christ Hospital, Cincinnati.

    Background: Experience with bortezomib (BTZ) antibody mediated rejection (AMR) therapy has progressively increased over the past few years. The BTZ toxicity profile in the transplant…
  • 2016 American Transplant Congress

    Pharmacist Impact on Medication Errors in a Chronic Kidney Transplant Clinic.

    K. Covert,1 C. Mardis,1 J. Fleming,1 A. Mardis,1 H. Meadows,1 N. Pilch,1 P. Mohan,2 M. Posadas,2 M. Salazar,2 T. Srinivas,2 G. Mour,2 D. Taber.1

    1Pharmacy, The Medical University of South Carolina, Charleston, SC; 2Transplant Nephrology, The Medical University of South Carolina, Charleston, South Carolina.

    Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to assess the impact of…
  • 2016 American Transplant Congress

    Simulating Alternative Bayesian Criteria to Identify Transplant Center Performance Outliers.

    J. Schold,1 C. Miller,1 M. Henry,2 L. Buccini,1 S. Flechner,1 D. Goldfarb,1 E. Poggio,1 K. Andreoni.3

    1Cleveland Clinic, Cleveland, OH; 2Ohio State University, Columbus, OH; 3University of Florida, Gainesville, FL.

    The newly constructed Bayesian models to evaluate transplant center performance were implemented in 2014. The rates and impact of the assumptions used for flagging centers…
  • 2016 American Transplant Congress

    High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients.

    D. Berglund,1 D. Schladt,2 K. Sanghavi,1 W. Guan,1 B. Wu,1 C. Dorr,3 R. Remmel,1 R. Mannon,4 A. Matas,1 W. Oetting,1 A. Israni,3 P. Jacobson,1 DeKAF Genomics Investigators.

    1UofMN, Mpls; 2MMRF, Mpls; 3HCMC, Mpls; 4UAB, Birmingham.

    Kidney tx recipients carry a high burden of comorbidities, and some of the medications for these conditions have genetic predictors of efficacy and toxicity. These…
  • 2016 American Transplant Congress

    Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.

    S. Yeager, A. Carlson, C. Truax, N. Kenyon, F. Ahmed, J. Corbett, F. Shihab, L. Smith.

    University of Utah Health Care, Salt Lake City, UT.

    Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…
  • 2016 American Transplant Congress

    Relationship Between Clinical Events and Everolimus Exposure at 12 Months in De Novo Renal Transplant Recipients.

    F. Shihab,1 Y. Qazi,2 S. Mulgaonkar,3 K. McCague,4 D. Patel,4 V. Peddi,5 D. Shaffer.6

    1University of Utah, Salt Lake City, UT; 2University of Southern California, Los Angeles, CA; 3Barnabas Health, West Orange, NJ; 4Novartis Pharmaceuticals Corporation, East Hannover, NJ; 5California Pacific Medical Center, San Francisco, CA; 6Vanderbilt University, Nashville, TN.

    We assessed the incidence of post-transplant biopsy-proven acute rejection (BPAR), graft loss and other adverse events (AEs) associated with everolimus (EVR) and tacrolimus (TAC) exposure…
  • 2016 American Transplant Congress

    In Their Own Words: Living Kidney Donors Who Develop Kidney Failure.

    L. Ross,1 C. Halverson,2 J. Wang,1 M. Poulson,3 J. Karlin,4 M. Crowley-Matoka.5

    1U Chicago, Chicago, IL; 2Anthropology, U Chicago, Chicago, IL; 3Georgetown U, Washington, DC; 4Family Medicine, UCSF, San Francisco, CA; 5Medical Humanities, Northwestern U, Chicago, IL.

    Background: Psychosocial data about living kidney donation have been collected for almost five decades. The results are almost uniformly positive, even in the early years…
  • 2016 American Transplant Congress

    Everolimus versus Mycophenolate Mofetil in Combination with Tacrolimus: A Propensity Score Matching Analysis in Liver Transplantation.

    P. de Simone,1 P. Carrai,1 A. Precisi,2 L. Coletti,1 D. Ghinolfi,1 F. Filipponi.1

    1Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospitals, Pisa, Italy; 2Laboratory, University of Pisa Medical School Hospital, Pisa, Italy.

    Background: No trial has so far investigated everolimus (EVR)-incorporating immunosuppressive regimens versus combined use of tacrolimus (TAC) and mycophenolate mofetil (MMF) in liver transplantation (LT).Materials…
  • 2016 American Transplant Congress

    Pre-Transplant Intra-Arterial Liver Directed Therapy Does Not Increase the Risk of Hepatic Arterial Misadventures in Liver Transplantation.

    J. Kallini,2 A. Gabr,2 R. Salem,2 R. Lewandowski,2 T. Baker.1

    1Comprehensive Transplant Center, Northwestern University, Chicago, IL; 2Division of Interventional Oncology, Northwestern University, Chicago, IL.

    Background: Pretransplant liver directed therapy has emerged as standard of care for patients with end stage liver disease complicated by unresectable hepatocellular cancer. The aim…
  • 2016 American Transplant Congress

    Earlier Repletion of Lymphocytes After Alemtuzumab Induction Is Associated with a Lower Incidence of Infection Following Renal Transplantation.

    M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Alemtuzumab has been increasingly used as an induction agent in renal transplantation, although the optimal dose is unknown. We have previously reported that alemtuzumab…
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