Articles tagged "Adverse effects"

2017 American Transplant Congress
Single-Center Initial Experience in Treating Chronic Hepatitis C in Kidney Transplant Recipients.
G. Meinerz, C. da Silva, R. Bruno, E. Keitel, V. Garcia.
Nephrology and Kidney Transplant Department, ISCMPA, Porto Alegre, RS, Brazil
Chronic hepatitis C (HCV) infection is a prevalent condition in end-stage renal disease and presents an important clinical challenge in kidney transplant recipients (KTR). Interferon-based…
2017 American Transplant Congress
Alemtuzumab Induction Is Safe, and Permits the Avoidance of Steroids in the Majority of Renal Transplant Recipients.
A. Seitz,¹ M. Robb,² N. Ahmad,¹ A. McLean,³ D. Taube,³ R. Johnson,² R. Baker.¹
¹Renal Unit, St James's Hospital, Leeds, United Kingdom; ²Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom; ³West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom
IntroductionThe introduction of alemtuzumab into routine clinical use has been hindered by safety concerns surrounding its prolonged effect on the lymphoid compartment. Here we report…
2017 American Transplant Congress
Systemic Immunosuppression in the Setting of Ocular Surface Stem Cell Transplantation.
A. Govil,¹ A. Cheung,² E. Sarnicola,² E. Holland.²
¹University of Cincinnati, Cincinnati, OH; ²Cincinnati Eye Institute, Cincinnati, OH
Purpose: To evaluate the success, tolerability, and side effects of systemic immunosuppression (SI) in patients undergoing ocular surface stem cell transplantation (OSST) under the SI…
2017 American Transplant Congress
Improvement of Cyclosporine A Dosing Strategy to Enhance Medication Adherence.
M. Barten,¹ E. Harmel,¹ M. Goldmann,¹ F. Wagner,¹ H. Reichenspurner,¹ M. Rybczynski.²
¹Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany; ²General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany
Background: It is known that the number of daily pills is crucial for medical adherence of patients after heart transplantation (HTx). For cyclosporine A (CsA)…
2016 American Transplant Congress
Anti-Thymocyte Globulin Induced Thrombocytopenia and Bleeding After Kidney Transplantation.
M. Dokus,¹ A. Patel,¹ J. Iuppa,² E. Venniro,³ A. Danzig,¹ J. Cooley,² J. Taylor,³ R. Kashyap,¹ M. Orloff.¹
¹Department of Surgery, Division of Transplant and Hepatobiliary Surgery, University of Rochester, Rochester, NY; ²Department of Pharmacy, University of Rochester, Rochester, NY; ³Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY.
Background: Bleeding is a significant challenge after renal transplantation. Anti-thymocyte globulin (ATG) induced thrombocytopenia may increase bleeding after kidney transplantation (KTx), but this association has…
2016 American Transplant Congress
Predictive Model for Medication Errors in a Chronic Kidney Transplant Clinic.
K. Covert,¹ C. Mardis,¹ J. Fleming,¹ A. Mardis,¹ H. Meadows,¹ N. Pilch,¹ P. Mohan,² M. Posadas,² M. Salazar,² T. Srinivas,² G. Mour,² D. Taber.¹
¹Pharmacy, The Medical University of South Carolina, Charleston, SC; ²Transplant Nephrology, The Medical University of South Carolina, Charleston, SC.
Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to create a model to…
2016 American Transplant Congress
Evaluation of the Toxicity Profile of Proteasome Inhibitor-Based Therapy for Antibody Mediated Rejection.
A. Leino,¹ A. Lichvar,¹ B. Abu-Jawdeh,¹ A. Govil,¹ G. Mogilishetty,¹ M. Cardi,² J. Kremer,² M. Cuffy,¹ F. Paterno,¹ R. Alloway,¹ A. Shields,^1,2 E. Woodle.¹
¹U of Cinncinati, Cincinnati; ²The Christ Hospital, Cincinnati.
Background: Experience with bortezomib (BTZ) antibody mediated rejection (AMR) therapy has progressively increased over the past few years. The BTZ toxicity profile in the transplant…
2016 American Transplant Congress
Pharmacist Impact on Medication Errors in a Chronic Kidney Transplant Clinic.
K. Covert,¹ C. Mardis,¹ J. Fleming,¹ A. Mardis,¹ H. Meadows,¹ N. Pilch,¹ P. Mohan,² M. Posadas,² M. Salazar,² T. Srinivas,² G. Mour,² D. Taber.¹
¹Pharmacy, The Medical University of South Carolina, Charleston, SC; ²Transplant Nephrology, The Medical University of South Carolina, Charleston, South Carolina.
Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to assess the impact of…
2016 American Transplant Congress
Simulating Alternative Bayesian Criteria to Identify Transplant Center Performance Outliers.
J. Schold,¹ C. Miller,¹ M. Henry,² L. Buccini,¹ S. Flechner,¹ D. Goldfarb,¹ E. Poggio,¹ K. Andreoni.³
¹Cleveland Clinic, Cleveland, OH; ²Ohio State University, Columbus, OH; ³University of Florida, Gainesville, FL.
The newly constructed Bayesian models to evaluate transplant center performance were implemented in 2014. The rates and impact of the assumptions used for flagging centers…
2016 American Transplant Congress
High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients.
D. Berglund,¹ D. Schladt,² K. Sanghavi,¹ W. Guan,¹ B. Wu,¹ C. Dorr,³ R. Remmel,¹ R. Mannon,⁴ A. Matas,¹ W. Oetting,¹ A. Israni,³ P. Jacobson,¹ DeKAF Genomics Investigators.
¹UofMN, Mpls; ²MMRF, Mpls; ³HCMC, Mpls; ⁴UAB, Birmingham.
Kidney tx recipients carry a high burden of comorbidities, and some of the medications for these conditions have genetic predictors of efficacy and toxicity. These…