Articles tagged "Adverse effects"

2017 American Transplant Congress
Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation.
D. Taber, Z. Su, A. Posadas, M. Gebregziabher, L. Egede, D. Dubay, J. McGillicuddy, C. Bratton, S. Nadig, K. Chavin, P. Baliga.
MUSC, Charleston, SC
Low tacrolimus (FK) trough concentrations have been associated with higher risk of acute rejection, particularly within African-American (AA) kidney transplant recipients; less is known about…
2017 American Transplant Congress
Applicability and Safety of a Regulatory T Cell Therapy in Adult Liver Transplantation: The “ThRIL” Phase I First-in-Human Trial.
G. Whitehouse, N. Safinia, S. Thirkell, L. Fry, N. Grageda, M. Martinez-Llordella, R. Lechler, N. Heaton, G. Lombardi, A. Sanchez-Fueyo.
MRC Centre for Transplantation, King's College London, London, United Kingdom
Aim“ThRIL” is a multiple site, open-label, uncontrolled, phase I clinical trial assessing the safety and applicability of a CD4+CD25+FOXP3+ regulatory T cell (Treg) immunotherapy in…
2017 American Transplant Congress
Dementia and Alzheimer's Disease Among Older Kidney Transplant Recipients.
M. McAdams DeMarco, S. Bae, N. Chu, A. Gross, C. Brown IV, E. Oh, P. Rosenberg, K. Neufeld, R. Varadhan, M. Albert, J. Walston, D. Segev.
Johns Hopkins, Baltimore, MD
Background: Kidney transplantation (KT) is a growing treatment option for older ESRD patients. Older recipients may develop post-KT dementia and Alzheimer's disease (AD) associated with…
2017 American Transplant Congress
Impact of Donor Asystole in Intestine Transplant.
J. Schroering, C. Kubal, R. Mangus.
Surgery, Indiana University, Indianapolis, IN
Intestine transplantation has a high risk of post-transplant complications. For this reason, many intestine transplant centers are conservative in their choice of deceased donors, using…
2016 American Transplant Congress
Outcomes of Untreated Asymptomatic Bacteriuria in Renal Transplant Recipients: A Single-Center Experience.
W. Davis, R.-A. Lee, L. Daniels, S. Todd, K. True, P. Chong.
University of North Carolina Medical Center, Chapel Hill, NC.
Background. Renal transplant recipients (RTR) with asymptomatic bacteriuria (AB) are often treated with antibiotics. This could lead to complications related to antibiotic treatment including Clostridium…
2016 American Transplant Congress
Schisandra Sphenanthera Extract Facilitates Anti-Tuberculosis Treatment Post Renal Transplantation Through Increasing Bioavailability of Tacrolimus.
R. Deng,¹ L. Zhang,¹ L. Liu,¹ H. Fu,² J. Li,¹ Q. Fu,¹ C. Wang.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Infectious Medicine Department, Guangzhou Infectious Disease Hospital, Guangzhou, China.
Background: Hepatoprotective agent Schisandra sphenanthera extract (SchE) facilitates rifampicin-containing anti-tuberculosis (TB) chemotherapy by stabilizing the Tacrolimus (FK506) blood concentration through increasing the oral bioavailability, which…
2016 American Transplant Congress
Long-Term vs Short-Term Valganciclovir Prophylaxis Use for Cytomegalovirus and Epstein-Barr Virus Infections in Pediatric Living Related Liver Transplantation.
T. Ueno,¹ H. Yamanaka,¹ Y. Takama,¹ N. Tanaka,¹ Y. Tazuke,¹ K. Bessho,² H. Okuyama.¹
¹Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan; ²Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan.
[Purpose] Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are the most important viral infections in pediatric patients with transplant. Valganciclovir (VGCV) has been used as…
2016 American Transplant Congress
Urgent Kidney Transplantation as Successful Treatment of Calciphylaxis in Three Patients with End-Stage Kidney Failure.
E. Nordheim,¹ D. Dahle,¹ I. Syse,¹ A. Åsberg,^1,2 A. Reisæter,¹ H. Holdaas,¹ T. Jenssen,^1,3 A. Hartmann.^1,4
¹Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ²Shool of Pharmacy, University of Oslo, Oslo, Norway; ³Kidney, Arctic University of Tromsø, Tromsø, Norway; ⁴Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.
Background: Calciphylaxis often referred to as calcific uremic arteriolopathy (CUA) is a rare and serious complication with limited treatment options. Kidney transplantation restores kidney function…
2016 American Transplant Congress
Anti-Thymocyte Globulin Induced Thrombocytopenia and Bleeding After Kidney Transplantation.
M. Dokus,¹ A. Patel,¹ J. Iuppa,² E. Venniro,³ A. Danzig,¹ J. Cooley,² J. Taylor,³ R. Kashyap,¹ M. Orloff.¹
¹Department of Surgery, Division of Transplant and Hepatobiliary Surgery, University of Rochester, Rochester, NY; ²Department of Pharmacy, University of Rochester, Rochester, NY; ³Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY.
Background: Bleeding is a significant challenge after renal transplantation. Anti-thymocyte globulin (ATG) induced thrombocytopenia may increase bleeding after kidney transplantation (KTx), but this association has…
2016 American Transplant Congress
Predictive Model for Medication Errors in a Chronic Kidney Transplant Clinic.
K. Covert,¹ C. Mardis,¹ J. Fleming,¹ A. Mardis,¹ H. Meadows,¹ N. Pilch,¹ P. Mohan,² M. Posadas,² M. Salazar,² T. Srinivas,² G. Mour,² D. Taber.¹
¹Pharmacy, The Medical University of South Carolina, Charleston, SC; ²Transplant Nephrology, The Medical University of South Carolina, Charleston, SC.
Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to create a model to…