ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Adverse effects"

  • 2022 American Transplant Congress

    The Impact of Long-Term Exposure to Tacrolimus on Chronic Kidney Disease Following Lung Transplantation: A Retrospective Analysis from a Single Transplantation Center

    D. Xiong, J. Zhang, J. Chen

    Lung Transplantation Center, Department of Thoracic Surgery, Wuxi People’s Hospital Affiliated to Nanjing Medical Univer, Wuxi, China

    *Purpose: Chronic kidney disease (CKD) is a progressive and irreversible complication in lung transplant patients who have received long-term treatment with tacrolimus. This study aimed…
  • 2022 American Transplant Congress

    The Sustained Impact of a Minimization Protocol on Peri-Operative Opioid Use in Kidney Transplantation

    N. Patel, T. Carcella, J. Marable, V. Rohan, S. Bethi, P. Baliga, D. Dubay, J. N. Fleming, D. Taber

    -MUSC, -Charleston, SC

    *Purpose: Opioid use following kidney transplant (KTX) is associated with higher graft and patient loss. Thus, in 2019 we implemented an opioid minimization quality improvement…
  • 2022 American Transplant Congress

    Conversion of Tacrolimus Immediate Release to LCP Tacrolimus in Obese Kidney Transplant Recipients

    J. Newman, N. Patel, S. Patel, T. Sprague, E. Andrade, N. Rao, F. Bartlett, D. DuBay, V. Rohan, M. Casey, D. Taber

    MUSC, Charleston, SC

    *Purpose: Data describing the safety, efficacy and conversion ratio of tacrolimus immediate release (IR) to LCP-tacrolimus (LCP) in obese patients (BMI > 30) is lacking.…
  • 2022 American Transplant Congress

    Prevalence of Mycophenolate Mofetil (MMF) Discontinuation and Outcomes in Pediatric Kidney Transplants (PKTX): A PNRC Study

    A. Moudgil1, K. Sgambat1, E. Benoit2, A. Jain3, M. Seifert4, C. Katsoufis5, L. Harshman6, A. Mansuri7, M. Somers8

    1Nephrology, Children's National Med. Ctr., Washington, DC, 2Nephrology, Boston's Children's Hospital, Boston, MA, 3Nephrology, Wayne State University, Troy, DC, 4Nephrology, The University of Alabama, Birmingham, AL, 5Nephrology, Holtz Children's Hospital, Miami, FL, 6Nephrology, University of Iowa, Iowa City, IA, 7Nephrology, Children's Hospital of Georgia, Augusta, GA, 8Nephrology, Boston Children's Hospital, Boston, MA

    *Purpose: MMF is discontinued in PKTX for various reasons. In this Pediatric Nephrology Research Consortium (PNRC) study, we determined prevalence and reasons for MMF discontinuation…
  • 2022 American Transplant Congress

    Safety and Mortality Benefit of Direct Oral Anticoagulants in Kidney Transplant

    C. Firth, M. Apolinario, F. Shamoun, E. Lim, N. Zhang, M. Keddis

    Mayo Clinic, Scottsdale, AZ

    *Purpose: Direct oral anticoagulants (DOACs) are increasingly used in renal transplant recipients (RTR). We aim to identify bleeding events and all-cause mortality between DOACs and…
  • 2022 American Transplant Congress

    Pericardial Effusion: A Potential Late Complication of COVID-19 Infection

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…
  • 2022 American Transplant Congress

    Incidence of Dapsone-Induced Methemoglobinemia in Solid Organ Transplant Recipients

    D. Quan1, R. Gordon1, J. Lee1, D. Khoshabafard2, A. Han1

    1Pharmacy, UCSF Medical Center, San Francisco, CA, 2Clinical Phamacy, UCSF School of Pharmacy, San Francisco, CA

    *Purpose: The purpose of this study was to determine the incidence of dapsone-induced methemoglobinemia in solid organ transplant recipients.*Methods: This was a single-center retrospective cohort…
  • 2022 American Transplant Congress

    Physiological Age by Artificial Intelligence-Enhanced Electrograms as a Novel Biomarker of Mortality in Kidney Transplant Candidates

    E. Lorenz, I. Zaniletti, B. Johnson, T. Petterson, W. Kremers, C. Schinstock, H. Amer, A. Cheville, N. LeBrasseur, A. Baez-Suarez, Z. Attia, F. Lopez-Jimenez, P. Friedman, C. Kennedy, A. Rule

    Mayo Clinic, Rochester, MN

    *Purpose: Assessing mortality risk prior to kidney transplantation is challenging. Age-Gap, which is the difference between physiological age determined by artificial intelligence-enhanced electrocardiograms (ECG) and…
  • 2022 American Transplant Congress

    Transplant Graft TMA Injury Post COVID-19 Vaccination

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: Vaccination against SARS-CoV-2 is essential. Complicating this effort are reports of a suboptimal response to the SARS-CoV-2 spike protein in patients on immunosuppressive medications…
  • 2022 American Transplant Congress

    Maribavir (MBV) versus Investigator-Assigned Therapy (IAT) for Refractory Cytomegalovirus (CMV) Infection (with or without Resistance) in Solid Organ Transplant (SOT) Recipients: Subgroup Safety Analysis of a Phase 3 Study

    R. M. La Hoz1, D. Florescu2, D. Kumar3, F. Saliba4, J. Gu5, A. Sundberg5

    1Univ. Texas Southwestern Medical Center, Dallas, TX, 2Univ. Nebraska Medical Center, Omaha, NE, 3Univ. Health Network, Toronto, ON, Canada, 4Univ. Paris Saclay, Paris, France, 5Takeda Development Center Americas, Inc., Lexington, MA

    *Purpose: In a Phase 3 study of MBV vs IAT (val/ganciclovir, foscarnet, or cidofovir) for refractory CMV infection (with/without resistance; R/R) in hematopoietic cell transplant…
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