2018 American Transplant Congress » Poster Session D: B-cell / Antibody

6:00pm-7:00pm

In Vivo Administration of Plerixafor and Bortezomib Results in Bone Marrow Plasma Cell Mobilization and Death While Inducing Biphasic Plasma Cell Apoptosis in Peripheral Blood

E. Woodle,¹ S. Tremblay,¹ C. Castro-Rojas,² S. Knechtle,³ A. Shields,¹ R. Alloway,¹ H. Singh,² J. Driscoll,¹ D. Hildeman.²

6:00pm-7:00pm

Accommodation and Antibody Mediated Rejection Are Associated with Distinct TACI Polymorphisms in Kidney Transplant Recipients

M. Cascalho, M. Barbosa,¹ E. Farkash,² J. Platt.¹

6:00pm-7:00pm

Analysis of Circulating CD38+/CD138+ Plasma Cells during Development of De Novo Donor Specific Antibody Responses

N-.N. Chai, G. Wu, I. Kim, S. Jordan, A. Klein.

6:00pm-7:00pm

BLyS^-/- Rats to Prevent Alloantibody Production

N. Bath,¹ B. Verhoven,¹ N. Wilson,¹ S. Reese,² L. Coons,¹ S. Panzer,² A. Djamali,² R. Redfield.¹

6:00pm-7:00pm

CD8-Expressing Transitional B Cells Dominate B Cell Reconstitution in Transplanted Monkeys Receiving Mixed Chimerism Conditioning

K. Pruner, J. Paster, S. Wiebke, O. Jane, H. Isabel, D. Abbas, B. Gilles, M. Joren.

6:00pm-7:00pm

Circulating T Follicular Helper Cells Expand Following Transplantation and Exhibit a CD44^hi Phenotype That Correlates with Peak Germinal Center Alloreactivity

G. La Muraglia II, M. Wagener, M. Ford, R. Badell.

6:00pm-7:00pm

Effects of Preformed Antibody on Survival Following Pig-to-Primate Liver Xenotransplantation

N. Louras, M. Patel, J. Shah, A. Andrews, Z. Wang, D. Sachs, P. Vagefi.

6:00pm-7:00pm

Graft Immunocomplex Capture Fluorescence Analysis Can Detect Intra-Graft Anti-Blood Group A/B Antibodies

T. Nakamura,¹ H. Ushigome,¹ Y. Imanishi,² S. Kawai,³ T. Shirouzu,³ M. Osaka,¹ K. Masuda,¹ T. Matsuyama,¹ S. Harada,¹ S. Nobori,¹ N. Yoshimura.¹

6:00pm-7:00pm

Increase on Regulatory Cells in Kidney Transplanted Patients Presenting Donor-Specific Antibodies

G. Maciel,¹ M. Fernandes,^1,2 E. Barbosa,² H. Rodrigues,¹ N. Panajotopolus,¹ F. Agena,² E. David-Neto,² V. Coelho,¹ M. Castro.²

6:00pm-7:00pm

Long Term Culture of Functional Bone Marrow-Derived Human Plasma Cells

N. Moore, K. Bonner, M. D'Costa, M. Stegall.

6:00pm-7:00pm

Multi-Targeting Desensitization Therapy Alters Peripheral B-Cell Homeostasis and Suppresses Recall Alloantibody Responses

I. Kim, G. Wu, N-.N. Chai, A. Klein, S. Jordan.

6:00pm-7:00pm

Preemptive B Cell Depletion Modulates Pathogenic Alloimmunity Associated with Selective Non-Activating CD28 Blockade

N. O'Neill,¹ T. Zhang,¹ W. Sun,¹ G. Braileanu,¹ X. Cheng,¹ I. Tatarov,¹ W. Hassanein,¹ Z. Habibabady,¹ B. Cerel,¹ K. Reimann,² A. Azimzadeh,¹ R. Pierson.¹

6:00pm-7:00pm

TACI Polymorphisms Associated with Allograft Rejection in Mice and in Man

M. Barbosa,¹ E. Farkash,² J. Platt,³ M. Cascalho.³

6:00pm-7:00pm

TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection

N. Wilson,¹ B. Verhoven,² B. Boldt,² N. Bath,² X. Ding,¹ R. Redfield III.²

6:00pm-7:00pm

Targeting Plasma Cells with Anti-CD38mAb (Daratumumab) and CXCR4 Antagonist (Plerixafor) for Desensitization

J. Kwun,¹ E. Brian,¹ M. Manook,¹ J. Park,¹ K. Freischlag,¹ J. Yoon,¹ J. Yi,¹ M. Stegall,² S. Knechtle.¹