2017 American Transplant Congress » Concurrent Session: Tolerance: Clinical Studies

Date: Sunday, April 30, 2017

Time: 4:30pm-6:00pm

Location: E353C

Session Type: Concurrent Session

Meeting: 2017 American Transplant Congress

4:30pm-4:42pm: Tolerant Pediatric Liver Transplant (LT) Recipients (TOL) from WISP-R (NCT00320606) Split into Two Phenotypically Distinct Groups by PD1 Expression on CD4+ T Cells at Baseline, Prior to Immunosuppression Withdrawal (ISW).

B. Burrell,¹ S. Feng,² N. Bridges,³ U. Ekong,⁴ S. Kanaparthi,¹ A. Kirk,⁵ A. Long,¹ K. Spain,⁶ L. Stempora,⁵ L. Turka,¹ N. Tchao.¹

4:42pm-4:54pm: Eight Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients.

J. Leventhal,¹ J. Galvin,¹ J. Mathew,¹ L. Gallon,¹ D. Stare,¹ A. Sweeney,¹ J. Miller,¹ M. Abecassis,¹ S. Ildstad.²

4:54pm-5:06pm: Relationship Between Mixed Chimerism and Tolerance in HLA-Matched and -Mismatched Recipients of Kidney and Hematopoietic Cell Transplants.

S. Busque, J. Scandling, J. Shizuru, R. Lowsky, A. Shori, J. Kent, E. Engleman, S. Strober.

5:06pm-5:18pm: A Molecular Signature Characterized by Dominance of Negative Regulation over Cytotoxic Effectors in Tolerant Kidney Allograft Recipients.

J. Lee,¹ J. Leventhal,² C. Li,¹ A. Katapodis,³ S. Ildstad,⁴ M. Suthanthiran.¹

5:18pm-5:30pm: Dominant Role of Clonal Deletion in Achieving Immune Tolerance After Unrelated Cord Blood Transplantation.

P. Szabolcs,^1,2 X. Chen,¹ M. Hill.¹

5:30pm-5:42pm: Impact of mTOR-Inhibition on Tolerance-Induction Following Heart Transplantation.

M.-T. Dieterlen, K. Klaeske, J. Fischer, J. Hahn, K. Jawad, J. Garbade, F. Mohr, S. Lehmann.

5:42pm-5:54pm: Applicability and Safety of a Regulatory T Cell Therapy in Adult Liver Transplantation: The “ThRIL” Phase I First-in-Human Trial.

G. Whitehouse, N. Safinia, S. Thirkell, L. Fry, N. Grageda, M. Martinez-Llordella, R. Lechler, N. Heaton, G. Lombardi, A. Sanchez-Fueyo.

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