Am J Transplant, Volume 5, Suppl 3 Archives - Page 96 of 170 - ATC Abstracts

2015 American Transplant Congress
Racial Differences in Transplant and Waitlist Mortality Rates Among HIV+ Kidney Transplant Candidates
J. Locke,¹ S. Gustafson,² C. Durand,³ J. Snyder,² B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ S. Mehta,¹ A. Nellore,¹ D. Segev.^2,3
¹University of Alabama, Birmingham, Birmingham, AL; ²SRTR, MMRF, Minneapolis, MN; ³Johns Hopkins Univerity, Baltimore, MD.
Kidney transplant (KT) is now a viable option for select HIV+ end-stage renal disease patients. As OPTN does not collect HIV status at waitlisting, no…
2015 American Transplant Congress
Tolerant Kidney Transplant Patients Display B Cells With Regulatory Properties
S. Brouard,^1,2 M. Chesneau,^1,3 L. Michel,^1,2,3 E. Dugast,^1,3 A. Chenouard,^1,3 A. Pallier,¹ D. Baron,^1,3 J. Durand,^1,3 F. Braza,^1,3 P. Guerif,² D.-A. Laplaud,^1,2,3 J.-P. Soulillou,^1,2,3 M. Giral,^1,2,3 N. Degauque,^1,3 E. Chiffoleau,^1,3 S. Brouard.^1,2
¹INSERM UMR 1064, Nantes, France; ²CHU de Nantes, ITUN, Nantes, France; ³Université de Nantes, Faculté de Médecine, Nantes, France.
Whereas a B cell transcriptional profile has been recorded for operationally tolerant kidney graft patients, the role that B cells may play in this process…
2015 American Transplant Congress
Development of a Risk Assessment Model for HIV Among Increased Risk Deceased Donors With Negative Nucleic Acid Testing
P. Annambhotla, B. Gurbaxani, M. Kuehnert, S. Basavaraju.
Centers for Disease Control and Prevention, Atlanta, GA.
Background: In 2013, guidelines for reducing the risk of HIV, hepatitis B and C disease transmission through organ transplants were released. These include criteria which…
2015 American Transplant Congress
Dendritic Cells in Kidney Transplant Biopsies Are Associated With Poor Allograft Survival
I. Batal,¹ S. De Serres,¹ K. Safa,¹ A. Waaga,¹ M. Onozato,² N. Najafian,¹ A. Chandraker.¹
¹Brigham and Women's Hospital/Harvard Medical School, Boston, MA; ²Massachusetts General Hospital/Harvard Medical School, Boston, MA.
Background: Long-term renal allograft survival continues to lag behind the progress seen in short-term transplant outcomes. Dendritic cells (DCs) are the most efficient antigen-presenting cells,…
2015 American Transplant Congress
Changes in Health Related Quality of Life (HRQOL) in Pediatric Liver Transplant (LT) Recipients During Protocolized Immunosuppression Withdrawal (ISW): The iWITH Trial
S. Mohammad,¹ S. Sundaram,² V. Venkat,³ M. Martinez,⁴ J. Lopez,⁵ J. Magee,⁵ E. Alonso,¹ S. Feng.⁶
¹Northwestern U, Chicago; ²U of Colorado, Aurora; ³U of Pittsburgh, Pittsburgh; ⁴Columbia U., New York; ⁵U of Michigan, Ann Arbor; ⁶UCSF, San francisco.
ISW may limit medication-related comorbidities but intensive monitoring and unexpected rejection episodes may compromise HRQOL. We studied longitudinal HRQOL in pediatric LT recipients undergoing ISW…
2015 American Transplant Congress
The Selection Process for Total Artificial Heart
F. Arabia, L. Czer, M. Kittleson, E. Passano, F. Liou, J. Yabuno, H. Henry, D. Chang, F. Esmailian, J. Kobashigawa, J. Moriguchi.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Heart failure patients with severe biventricular failure who are candidates for heart transplant are considered for Total Artificial Heart (TAH) support. These patients may…
2015 American Transplant Congress
Failure to Account for Critical Candidate Characteristics Significantly Biases Kidney Transplant Center Report Cards Measuring Time to Transplant
L. Kayler,¹ J. Schold.²
¹Surgery, Montefiore Medical Center, Bronx, NY; ²Medicine, Cleveland Clinic, Cleveland, OH.
Kidney transplant rate is proposed to be integrated into the new composite metric to evaluate center performance. Current methods adjust for PRA, blood type, re-transplantation,…
2015 American Transplant Congress
Matching Strategies in Kidney Paired Donation: A 7-Year Analysis of a Multi-Institutional Registry
D. Fumo,^1,2 L. Reece,² S. Stepkowski,¹ V. Kapoor,¹ S. Rees,² J. Kopke,² M. Rees.^1,2
¹University of Toledo Medical Center, Toledo, OH; ²Alliance for Paired Donation, Maumee, OH.
Failure to convert computer-identified possible Kidney Paired Donation (KPD) exchanges into transplants has prevented KPD from reaching its full potential. The purpose of this study…
2015 American Transplant Congress
Negative Effects of Being Obese or Overweight on T Regulatory (Treg) Cell Suppressive Function in Patients Listed for Lung Transplantation (Tx)
T. Akimova,¹ J. Diamond,² D. Wilkes,³ D. Lederer,⁴ J. Christie,² W. Hancock.¹
¹Path & Lab Med, CHOP & UPenn, Philadelphia; ²Pulm, Allergy & Crit Care Med, UPenn, Philadelphia; ³Med, Microbiol & Immunol, Indiana Uni Sch of Med & Thoracic Transplant Prog, Indianapolis; ⁴Medicine, Columbia Uni, New York.
Aim: Obese and overweight patients may be prone to adverse outcomes following lung Tx. We sought to determine the relationship between body mass index (BMI)…
2015 American Transplant Congress
Ex Vivo Expansion With Rapamycin Enhances the Suppressive Function of Regulatory T Cells (Tregs) Isolated from Pediatric Thymus
E. Dijke,^1,2,3 R. Hoeppli,^3,4 T. Ellis,^1,2 J. Pearcey,^1,2 I. Larsen,^1,2 I. Rebeyka,^1,2 D. Ross,^1,2 M. Levings,^3,4 L. West.^1,2,3
¹University of Alberta, Edmonton, AB, Canada; ²Alberta Transplant Institute, Edmonton, AB, Canada; ³Canadian National Transplant Research Program, Edmonton/Vancouver, AB/BC, Canada; ⁴University of British Columbia, Vancouver, BC, Canada.
INTRODUCTION: Treg-based cellular therapy to suppress graft-directed immunity could reduce the need for life-long immunosuppressive drugs. Challenges include isolation and expansion of pure Tregs to…