Am J Transplant, Volume 5, Suppl 3 Archives - Page 82 of 170 - ATC Abstracts

2015 American Transplant Congress
Kidney Transplantation in the Septuagenarian
H. Saucedo Crespo, B. Taner, M. Mai, H. Wadei, P. Perry, M. Prendergast, J. Nguyen, K. Oshel, J. Bruns, D. Lee, T. Gonwa.
Department of Transplantation, Mayo Clinic, Jacksonville, FL.
The elderly ESRD population in the US continues to grow. National data demonstrates that both patient (PS) and graft survival (GS) at 1 and 5…
2015 American Transplant Congress
Clinical Significance of Estimated DSA MFI Values at 1,000 C1q MFI for Differentiation Between Harmful and Harmless DSA
K. Horimi,¹ T. Akaza,² K. Kuroki,² S. Sakamoto,² Y. Matsuoka,¹ Y. Watarai,² S. Narumi,² A. Katayama,³ K. Uchida,¹ T. Kobayashi.⁴
¹Aichi Medical University, Nagkute, Japan; ²Nagoya Daini Red Cross Hospital, Nagoya, Japan; ³Masuko Memorial Hospital, Nagoya, Japan; ⁴Nagoya University School of Medicine, Nagoya, Japan.
INTRODUCTIONControl of chronic antibody mediated rejection (CAMR) is essential for further improvement of long-term graft survival. Early detection of de novo donor specific antibodies (DSA)…
2015 American Transplant Congress
Validation of a Blood and Biopsy Gene Expression-Based Molecular Diagnostics for Subclinical Acute Rejection: Comparing DNA Microarrays Vs. Next-Generation RNA Sequencing
S. Kurian,¹ J. Friedewald,² F. Harrison,¹ T. Gelbart,¹ S. Head,¹ P. Ordoukhanian,¹ M. Abecassis,² D. Salomon.¹
¹The Scripps Research Institute, La Jolla, CA; ²Northwestern University, Chicago, IL.
Background: Microarray-based gene expression signatures for clinical diagnostics are well described. However, microarrays lack advantages offered by newer technologies such as Next Generation Sequencing (NGS):…
2015 American Transplant Congress
Urinary Cell-Free DNA Is a Sensitive Marker of Early Renal Transplant Injury
T. Sigdel, T. Tran, S.-C. Hsieh, M. Sarwal.
Surgery, UC San Francisco, San Francisco, CA.
Introduction:Circulating donor-derived cell-free DNA (dd-cfDNA) has been reported as a surrogate of transplant injury in the blood but requires expensive donor and recipient DNA sequencing.Method:…
2015 American Transplant Congress
Mononuclear Cell Infiltrates Characterization in Scar Tissue from a Bilateral Forearm Transplant Patient: Findings to Think
J. Furuzawa-Carballeda,¹ M. Iglesias,² J. Alberu,³ A. Gamboa,⁴ P. Butrón,² M. Morán-Romero,² Y. Esquivel.¹
¹Immunology, INCMNSZ, Mexico City, Mexico; ²Plastic Surgery, INCMNSZ, Mexico, Mexico; ³Transplants, INCMNSZ, Mexico, Mexico; ⁴Pathology, INCMNSZ, Mexico City, Mexico.
Herein we report the cell infiltrating pattern in scar tissue resected at the junction of the VCA and the tissue corresponding to the recipient arm,…
2015 American Transplant Congress
The Predictive Value of the Proliferation Marker Ki-67 in Patients With Fulminant Hepatic Failure
A. Shah,¹ U. Joneja,² D. Walls,¹ J. Farber.²
¹Surgery, Thomas Jefferson University, Philadelphia, PA; ²Pathology, Thomas Jefferson University, Philadelphia, PA.
This study aimed to evaluate the prognostic significance of the cellular proliferation marker Ki-67 in the liver biopsies of patients with fulminant hepatic failure.Under IRB…
2015 American Transplant Congress
IgM+ Antigen Binding B Cells in Peripheral Blood Regulate IFNγ Production in Response to HLA Proteins
L. McLaughlin,¹ K. Shiu,¹ G. Lombardi,¹ J. Spencer,² R. Vaughan,¹ A. Dorling.¹
¹MRC Centre for Transplantation, King's College London, London, United Kingdom; ²Peter Gorer Department of Immunobiology, King's College London, London, United Kingdom.
Chronic antibody mediated rejection (CAMR) is a major cause of graft loss in renal transplant recipients. Previous work utilising an IFNγ ELISPOT assay revealed two…
2015 American Transplant Congress
Association Between the Timed Up and Go Test and Waitlisting for Kidney Transplantation
M. Chiles,¹ K. Foley,¹ R. Crew,¹ G. Dube,¹ H. Morris,¹ S. Patel,² J. Camacho,² D. Cohen,¹ L. Ratner,² S. Mohan.¹
¹Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY; ²Department of Surgery, Columbia University College of Physicians & Surgeons, New York, NY.
Introduction: The Timed Up and Go Test (TUGT) is a test of balance, mobility and functional capacity. Longer times on the TUGT are associated with…
2015 American Transplant Congress
Kidney Transplantation from Expanded Criteria Deceased Donors With Terminal Acute Kidney Injury
J. Hwang,¹ M.-H. Kim,¹ K. Jun,¹ S. Ahn,¹ S. Kim,¹ S. Park,¹ S. Kim,² J. Kim,¹ C. Yang,² I. Moon.¹
¹Surgery, The catholic University of Korea, Seoul, Korea; ²Internal Medicine, The catholic iniversity of Korea, Seoul, Korea.
We investigated clinical outcomes of kidney transplantation (KT) from deceased donors with terminal acute kidney injury (AKI) defined acute kidney injury network (AKIN) criteria and…
2015 American Transplant Congress
Alemtuzumab Induction Is Associated With a Lower Risk of Early Rehospitalization After Kidney Transplant
G. Dube,¹ D. Tsapepas,² Y. Coppleson,³ L. Ratner,⁴ D. Cohen,¹ S. Mohan.¹
¹Medicine, Columbia University Medical Center, New York, NY; ²Pharmacy, New York-Presbyterian Hospital, New York, NY; ³Quality and Patient Safety, New York-Presbyterian Hospital, New York, NY; ⁴Surgery, Columbia University Medical Center, New York, NY.
Early rehospitalizations within the first 30 days (R-30D) are common after kidney transplant. R-30D are costly and associated with an increased risk of graft failure…