ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    A Tool for Predicting Long Term Risks of Kidney Donation

    S. Reule,1 R. Foley,1 A. Matas,2 H. Ibrahim.1

    1Department of Medicine, University of Minnesota, Minneapolis, MN; 2Department of Surgery, University of Minnesota, Minneapolis, MN.

    Background:The evidence linking kidney donation to a slightly increased risk of ESRD has now been accepted. The underlying causes of ESRD majority of donors who…
  • 2015 American Transplant Congress

    The Effects of Various Cardiac Preservation Solutions on Survival After Heart Transplantation

    C. Evans, K. Rajagopal, P. Sanchez, S. Rahimpour, F. Cheema, R. Pierson III, B. Griffith, S. Pham.

    Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD.

    Purpose: The optimal cardiac preservation solution is still debated. The purpose of this study is to determine whether the type of cardiac preservation solution has…
  • 2015 American Transplant Congress

    Increased Use of Donors After Cardiac Death (DCD) in Pancreas Transplantation: A Safe and Effective Way to Increase a Single Center Program Activity

    M. Marquez, G. Sapisochin, J. Laurence, A. Barbas, M. Dib, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattral.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    The SRTR database shows that DCD donors are rarely used for pancreas transplantation in the USA (< 3% in 2010 -2012). This low rate likely…
  • 2015 American Transplant Congress

    Impact of Donor Hemoglobin A1c On Pancreas Graft Survival

    K. Collins,1 J. Garonzik-Wang,1 E. King,2 M. Doyle,1 J. Lowell,1 S. Shenoy,1 Y. Lin,1 J. Wellen,1 W. Chapman,1 D. Segev.2

    1Abdominal Transplant, Washington University, Saint Louis, MO; 2Surgery, Johns Hopkins University, Baltimore, MD.

    A goal in selection of ideal donor pancreata is to avoid grafts with a predisposition to type-two diabetes. The HgA1c assay is a validated estimate…
  • 2015 American Transplant Congress

    End-To-End Ureteropyelostomy With Ligation of the Native Ureter in Kidney Transplantation: Is It a Safe Procedure?

    H. Marinho Neto,1 B. Leslie,1 J. Neves Neto,1 M. Almeida,1 S. Ximenes,1 W. Aguiar,1 H. Tedesco,2 J. Medina Pestana,2 R. Soler.1

    1Urology, Federal University of São Paulo, São Paulo, Brazil; 2Nephrology, Federal University of São Paulo, São Paulo, Brazil.

    INTRODUCTION:Ureteropyelostomy is an alternative for urinary tract reconstruction in kidney transplantation in cases where the graft ureter is not available or the recipient bladder is…
  • 2015 American Transplant Congress

    Blood Gene Expression at 3 Months Post-Transplantation Predicts 1-Year Histological Features in Renal Transplantation

    R. Danger,1,2 K. Renaudin,1,3,4 C. Paul,1 G. Couvrat-Desvergnes,1,3 J. Lozano,5 A. Sanchez-Fueyo,2,5 V. Meas-Yedid,6 J. Olivo-Marin,6 E. Thervet,7 J. Dantal,1,3,4 A. Moreau,1,3,4 J.-P. Duong Van Huyen,8 J.-P. Soulillou,1,3,4 M. Giral,1,3,4 S. Brouard.1,3,4

    1INSERM U1064 and ITUN, Nantes, France; 2Department of Liver Sciences, Faculty of Life Sciences & Medicine, MRC Transplant Centre, King's College London, London, United Kingdom; 3Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France; 4Universite de Nantes, Nantes, France; 5Liver Unit and Bioinformatic Platform, CIBEREHD, Hospital Clinic Barcelona, Barcelona, Spain; 6Unité d'Analyse d'Image Quantitative, Institut Pasteur, Paris, France; 7Nephrology Unit, Hôpital Européen Georges Pompidou, Paris, France; 8Service d'Anatomie Pathologique, Hôpital Européen Georges Pompidou, Paris, France.

    Histological analysis of biopsy at one year is proposed as a reliable tool for assessing renal allograft status, however, a non-invasive method for early prediction…
  • 2015 American Transplant Congress

    Molecular Marker Strategies Supporting the Novartis US92 Study- A Discovery Study of Protein Biomarkers for Kidney Function (eGFR) and Acute Rejection in Serum from Renal Transplant Patients

    U. Christians,1 J. Klepacki,1 A. Karimpour-fard,1 G. Ingle,2 D. Patel,2 K. Johnson,3 D. Cibrik,3 J. Klawitter.1

    1University of Colorado, Anschutz Medical Campus, Aurora, CO; 2Novartis Pharmaceuticals, East Hanover, NJ; 3University of Michigan Medical School, Ann Arbor, MI.

    Purpose. Protein biomarkers have the potential to allow for earlier and more specific diagnosis of kidney injury in kidney transplant patients than established clinical markers…
  • 2015 American Transplant Congress

    Associations Between Deceased-Donor Urine Biomarkers of Kidney Injury and 6-Month Kidney Transplant Function

    C. Parikh, I. Hall, M. Doshi, B. Schroppel, F. Weng, R. Hasz, P. Murray, V. Rao, H. Thiessen-Philbrook, J. Ficek, P. Reese.

    TRIBE-AKI Consortium, New Haven, CT.

    Assessment of organ quality is integral to allocation, yet existing tools have a limited ability to predict important transplant outcomes. We evaluated whether injury biomarkers,…
  • 2015 American Transplant Congress

    Socioeconomic Predictors of Organ Donation in Pediatric Donors

    M. Shah, V. Vilchez, A. Goble, E. Maynard, R. Gedaly.

    Transplant Surgery, University of Kentucky, Lexington, KY.

    BACKGROUND: The availability of pediatric donors does not meet the demand for pediatric recipients who are listed and waiting transplantation. There is a need to…
  • 2015 American Transplant Congress

    Overexpression of 2B4 Inhibits the Expansion and Function of Donor-Reactive CD8+ T Cells in Selective Lymphoid Compartments

    S. Laurie, D. Liu, M. Ford.

    Department of Surgery, Emory University, Atlanta, GA.

    2B4 is an immunoglobulin superfamily member expressed constitutively on NK cells, and inducibly on some CD8+ T cells. We recently showed in a murine skin…
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