ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Cyclophosphamide as a Salvage Therapy for Combined Intravenous Immunoglobulins and Plasmapheresis Refractory Antibody-Mediated Rejection

    W. Habhab,1 A. Dada,2 M. Alwassia,1 N. Baz,2 N. Zabani,1 A. Fahmy,1 A. Abdul Malik.1

    1Nephrology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; 2Pathlogy, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.

    Acute antibody-mediated rejection (AMR) poses a significant risk to graft survival. Current or standard treatment (ST) of AMR currently consists of plasmapheresis (PP), intravenous immunoglobulin…
  • 2015 American Transplant Congress

    Kidney Patients at High Immunological Risk Can Be Safely Transplanted With a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab

    D. Halleran,1 J. Melancon,2 V. Whittaker.1

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: We report the outcomes from our single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative…
  • 2015 American Transplant Congress

    Effect of Induction in Renal Transplant Recipients Aged 70 and Over

    M. Lubetzky, M. Ajaimy, L. Kamal, G. DeBoccardo, E. Akalin.

    Transplantation, Montefiore Medical Center, Bronx, NY.

    While there is a significant survival advantage to transplanting patients 70 years of age and older versus staying on dialysis, it is unclear whether sensitized…
  • 2015 American Transplant Congress

    Pre-Transplant Weight Change and New-Onset Diabetes After Kidney Transplantation

    E. Huang, B. Abdalla, M. Andre, S. Bunnapradist.

    Dept of Medicine, UCLA School of Medicine, Los Angeles, CA.

    Background:We studied the association between pre-transplant weight change and new-onset diabetes after kidney transplant (NODAT).Methods:Using OPTN/UNOS data with follow-up to October, 2012, all adult (age>18…
  • 2015 American Transplant Congress

    High Tolerability With Sofosbuvir-Based Direct-Acting Antiviral Therapy in Liver Transplant Recipients With Recurrent Hepatitis C

    B. Osborne,1 A. Modi,1 M. Gautam,1 N. Murray,1 I. Gonzalez,2 J. McAfee,2 S. Gonzalez.1

    1Hepatology, Baylor Simmons Transplant Institute, Fort Worth, TX; 2Hepatology, Liver Consultants of Texas, Fort Worth, TX.

    Background: Reports on efficacy, safety, and tolerability of sofobuvir-based antiviral regimens in liver transplant recipients with recurrent hepatitis C are limited. Methods: We performed a…
  • 2015 American Transplant Congress

    Plasmapharesis, Intravenous Immunoglobulin and Rituximab Successfully Treat Recurrent Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC-2) After Liver Transplantation

    H. Elsiesy,1 F. Abaalkhail,1 W. Alhamoudi,1,2 H. Alhussaini,3 M. Alsebayel,1 D. Broring,1 M. Shagrani.1

    1Liver Trasplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; 2Gastroenterology, King Saud University, Riyadh, Saudi Arabia; 3Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

    Background:Allo-immune mediated BSEP dysfunction may occur after liver transplantation in PFIC2 patients leading to a PFIC2 like phenotype. The IgG antibodies are reactive toward a…
  • 2015 American Transplant Congress

    Neurocognitive Profile of Children Born to Kidney Transplant Recipients Mothers

    L. Morales-Buenrostro,1 S. Sanchez-Roman,1 S. Lascarez,1 A. Niebla-Cardenas,1 D. Lopez-Carrillo,1 G. Caballero-Andrade,1 A. Velez,4 R. Espinoza,2 E. Mancilla-Urrea,3 J. Alberu.1

    1INCMNSZ, Mexico City, Mexico; 2Centro Medico Nacional Siglo XXI, Mexico City, Mexico; 3Instituto Nacional de Cardiologia, Mexico City, Mexico; 4Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.

    Aim. To compare neurocognitive abilities of children of kidney transplant (KT) recipients who were exposed to immunosuppression during pregnancy with unexposed children. Methods. In this…
  • 2015 American Transplant Congress

    Anti-CD122 + Costimulation Blockade Prolongs Allograft Survival

    D. Mathews,1 L. Higginbotham,1 Y. Dong,1 C. Breeden,1 C. Larsen,1 J. Tso,2 A. Adams.1

    1Emory Transplant Center, Emory University, Atlanta, GA; 2JN Bioscience, Mountanview, CA.

    Introduction: Effective T cell activation and effector function requires (1) cognate antigen recognition (2) appropriate costimulation and (3) successful cytokine signaling. Recently approved strategies to…
  • 2015 American Transplant Congress

    Feasibility of Regulatory T Cell Cryopreservation and Banking for Clinical Therapeutic Applications

    K. Gołąb,1 O. Savari,1 S. Ramachandran,1 Z. Tekin,1 M. Tibudan,1 J. Millis,1 P. Trzonkowski,2 P. Witkowski.1

    1Surgery, University of Chicago, Chicago, IL; 2Immunology, Medical University of Gdansk, Gdansk, Poland.

    Feasibility of clinical application of regulatory T cells (Tregs) in clinical transplantation would be improved if Tregs or pre-enriched cells for Treg isolation could be…
  • 2015 American Transplant Congress

    Pre-Operative Assessment of Body Composition in Adult Multivisceral Transplant Candidates

    R. Cruz, H. Sogawa, G. Bond, K. Soltys, R. Sindhi, G. Mazariegos, A. Humar, A. DiMartini.

    Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    Body Mass Index is commonly used, but is likely to be an inexact measurement of nutritional status. For this reason, we examined whether body composition…
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