Am J Transplant, Volume 5, Suppl 3 Archives - Page 74 of 170 - ATC Abstracts

2015 American Transplant Congress
Predictors of Time to Recurrence and Mortality Associated With Recurrent Hepatocellular Carcinoma After Liver Transplantation
A. Bodzin, D. Reino, K. Lunsford, M. Harlander-Locke, D. Markovich, A. Zarrinpar, F. Kaldas, D. Farmer, R. Busuttil, V. Agopian.
Transplantation, UCLA, Los Angeles, CA.
Background: While recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) portends a poor prognosis, adjuvant therapy may prolong survival. We sought to identify factors that…
2015 American Transplant Congress
Blocking CD4 T Cell Helper Functions Improves Efficacy of ATG Treatment in Sensitized Transplant Recipients
K. Ayasoufi, X. Wang, H. Yu, V. Gorbacheva, F. Ran, R. Fairchild, A. Valujskikh.
Immunology, Cleveland Clinic, Cleveland, OH.
Antibody mediated lymphocyte depletion is used in clinical transplantation to improve graft function. While the presence of donor-reactive memory T cells is the primary rationale…
2015 American Transplant Congress
Rat Forelimb Allotransplantation: A Novel Microsurgical Model for Optimized Functional Assessment After Reconstructive Transplantation
B. Kern,¹ S. Tuffaha,¹ M. Khusheim,¹ S. Xiang,¹ G. Furtmueller,¹ K. Sarhane,¹ J. Park,² A. Hoke,² W. Lee,¹ G. Brandacher.¹
¹Plastic & Reconstructive Surgery, Johns Hopkins University, Baltimore, MD; ²Neurology and NeuroSurgery, Johns Hopkins University, Baltimore, MD.
Background:Functional outcomes following vascularized composite allotransplantation (VCA) have been promising, but there is still room for improvement. Studies to investigate strategies to overcome this obstacle…
2015 American Transplant Congress
Effective Control of Anti-Xenogeneic IL-17 Response for Tolerance Induction in Xenogeneic Islet Cell Transplantation
H. Kang,¹ S. Wang,^1,2 X. Zhang,³ L. Zhang,¹ S. Miller,⁴ B. Hering,⁵ X. Luo.^1,3,4
¹Medicine, Northwestern University Feinberg school of Medicine, Chicago, IL; ²Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China; ³Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL; ⁴Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL; ⁵Schulze Diabetes Institute, University of Minnesota, Minneapolis, MN.
We have previously shown that peri-transplant infusion of donor cells treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (ECDI) in combination with peri-transplant anti-CD20 and rapamycin induce permanent porcine islet…
2015 American Transplant Congress
Cardiac Troponin T (cTNT) in the Assessment of Kidney Transplant (KTx) Benefit and Risk
F. Cosio,¹ A. Grupper,¹ P. Dean,² H. Amer.¹
¹Nephrology, Mayo Clinic, Rochester, MN; ²Surgery, Mayo Clinic, Rochester, MN.
Introduction. Compared to waiting list (WL) KTx improves patient survival. However, mortality may increase early post-KTx. cTNT level at candidate evaluation is a strong, independent…
2015 American Transplant Congress
Bridging Therapy With Belatacept in High MELD Liver Transplant Recipients
T. Sparkes,¹ B. Masters,¹ S. Hanish,² D. Potosky,² W. Hutson,² J. LaMattina,² R. Barth.²
¹University of Maryland Medical Center, Baltimore; ²University of Maryland School of Medicine, Baltimore.
Background: Poor outcomes of high-MELD liver transplant recipients are driven by multisystem organ dysfunction. Renal failure post-transplant has been associated with mortality of greater than…
2015 American Transplant Congress
Hospital Re-Admission After Intestinal Transplantation
Y. Kwon,¹ R. Girlanda,¹ A. Sharp,² K. Etesami,¹ J. Hawksworth,¹ C. Desai,¹ E. Island,¹ C. Matsumoto,¹ T. Fishbein.¹
¹MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC; ²Georgetown University School of Medicine, Washington, DC.
Aim. Intestinal transplant (ITx) recipients frequently require repeat hospital admissions after successful transplant, increasing costs and causing significant burden on families. The causes of hospital…
2015 American Transplant Congress
Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?
A. Schwarz,¹ S. Linnenweber-Held,¹ H. Haller,¹ A. Heim,² C. Schmitt.²
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Virology, Hannover Medical School, Hannover, Germany.
Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…
2015 American Transplant Congress
External Validation of Clinical Prediction Models of Patient and Graft Survival in a Canadian Cohort of Kidney Transplant Recipients
S. Singh,^1,2 D. Naimark,^1,2,3 J. Victor,² J. Kim.^1,2,4,5
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; ³Division of Nephrology, Sunnybrook Health Sciences Center, Toronto, ON, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, University Health Network, Toronto, ON, Canada; ⁵Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.
Background: Several clinical prediction models (CPM) of patient and graft survival in kidney transplant recipients have been developed as tools to assist physicians in identifying…
2015 American Transplant Congress
Characteristics and Consequences of Renal Allograft Rejections Due to Nonadherence
S. Patel, S. Kuten, J. Everett, J. Loucks-DeVos, L. Gaber, A. Gaber, R. Knight.
Houston Methodist Hospital, Houston.
Non-adherence (NA) with immunosuppressive medications is associated with increased healthcare costs, rejection risk, and graft loss. NA is difficult to measure, however, and is often…