2015 American Transplant Congress
Survival Benefit of ECD Transplantation After Ultra-Long Dialysis Exposure: Implications for Acceptance in the New KAS
Division of Nephrology, University of British Columbia, Vancouver, BC, Canada.
The survival benefit of ECD transplantation varies with the duration of pre-transplant dialysis exposure.We analyzed the survival benefit of ECD transplantation (Kidney Donor Profile Index…2015 American Transplant Congress
Association Between Histological Abnormalities in Time-Zero Renal Biopsies and Post-Donation eGFR in Live Donors
Time-zero biopsies (T0-RBx) of live-donor kidneys may reveal histological abnormalities at the time of organ recovery. The association between T0-RBx and subsequent kidney function in…2015 American Transplant Congress
Comparison of T Regulatory (Treg) Cell Function Pre- and Post-Lung Transplantation Shows a Major Negative Impact of Immunosuppression on Treg Function
Aim: Clinical lung Tx recipients do not have sustained long-term survival outcomes comparable to that of other recipients of solid organ allografts, despite generally comparable…2015 American Transplant Congress
Generation, Cryopreservation, Function and In Vivo Fate of Ex-Vivo Expanded Cynomolgus
Background:Foxp3+ regulatory T cells (Treg) function to promote immune tolerance and prevent immunopathogenesis. Preclinical studies have demonstrated that adoptive transfer of Treg prevents rejection of…2015 American Transplant Congress
CD4 T Cell Mediated Help Is Required for Endogenous Memory CD8 T Cell Proliferation in Cardiac Allografts Subjected to Prolonged Cold Ischemic Storage
Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts and produce IFN-γ in response to donor class І MHC within 24 hrs after graft reperfusion…2015 American Transplant Congress
Donor-Derived Cell-Free DNA Is Stable in Non-Rejecting Heart Transplant Recipients in the CARGO II Multicenter Trial
1CareDx, Inc, Brisbane, CA; 2Drexel University, University of Philadelphia, Philadelphia, PA.
Purpose: An elevated fraction of donor-derived cell-free DNA (dd-cfDNA) detected in the venous blood of recipients has been shown to be correlated to rejection of…2015 American Transplant Congress
The Significant Association Between the Functional Polymorphism (Rs3761548) of Foxp3 Gene and the Severity of Acute Cellular Rejection in Liver Transplantation
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Aim- Acute cellular rejection (ACR) accounts for 15-25% of graft failure in living donor liver transplantation (LDLT). T regulatory cells (Treg) play an important role…2015 American Transplant Congress
Early Hospital Readmissions After Kidney Transplantation
Transplantation, Montefiore Medical Center, Bronx, NY.
Early rehospitalization after kidney transplantation is common and is considered a quality metric. Few studies have examined preventability or specific transplant/discharge factors associated with early…2015 American Transplant Congress
Umbilical Vein Catheter Versus Double J Stent for Ureteric Anastomosis in Renal Transplantation: A Single Centre, Open Label, Randomized Trial
Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.
Introduction: Double J (DJ) stents are used routinely in renal transplantation to prevent ureteric complications. A recent Cochrane review of literature showed that routine prophylactic…2015 American Transplant Congress
10 Year Experience Using a Steroid Free Three Drug Maintenance Immunosuppression Regimen for Pancreas Transplant Alone: Comparison of Induction With Rabbit Antithymocyte Globulin +/- Rituximab
Graft survival following pancreas transplant alone (PTA) is inferior to other pancreas transplants. Steroid elimination is appealing, but a two drug maintenance strategy may be…
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