Am J Transplant, Volume 5, Suppl 3 Archives - Page 63 of 170 - ATC Abstracts

2015 American Transplant Congress
Proteasome Inhibition by Bortezomib Prevents Early Graft Failure After Pancreatic Islet Transplantation
H. Ono,¹ Y. Asahi,¹ T. Yoshida,¹ Y. Koshizuka,¹ M. Watanabe,¹ U. Tomaru,² S. Emoto,¹ M. Fukai,³ A. Taketomi,¹ S. Todo,⁴ K. Yamashita.³
¹Gastroenterological Surgery1, Hokkaido University Graduate School of Medicine, Sapporo, Japan; ²Department of Pathology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; ³Department of Transplant Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan; ⁴St Mary's Hospital, Kurume, Japan.
Background: Islet graft loss caused by injurious inflammatory and innate immune responses, is a major obstacle in pancreatic islet transplantation (PIT). In this pathophysiology, the…
2015 American Transplant Congress
Mesenchymal Stromal Cells (MSCs) Given Post-Transplant Together With C3a and C5a Receptor Antagonists Prevent Engraftment Syndrome and Induce a Mild Not-Significant Prolongation of Graft Survival
F. Casiraghi,¹ M. Todeschini,¹ N. Azzollini,¹ P. Cravedi,² P. Heeger,² P. Cassis,¹ S. Solini,¹ N. Perico,¹ M. Noris,¹ G. Remuzzi.¹
¹IRCSS Mario Negri Institute, Bergamo, Italy; ²Icahn School of Medicine at Mount Sinai, New York, NY.
Bone marrow (BM)-derived MSC given the day before kidney allografts localize into lymphoid organs and induce significant prolongation of graft survival in mice. By contrast,…
2015 American Transplant Congress
Lipid Profiles Over 2 Years Follow-Up in De Novo Kidney Transplant Recipients Randomized to Once-Daily MeltDose® Tacrolimus (Envarsus® XR) Vs. Twice-Daily Tacrolimus (Prograf®): Results from a Phase 3, Double-Blind, Double-Dummy, Multicenter Trial
S. Mulgaonkar, O. Pankewycz, S. Steinberg.
St. Barnabas Medical Center, Livingston; Erie County Medical Center, Buffalo; California Institute of Renal Research, San Diego.
Cardiovascular disease (CVD) is a leading cause of death in kidney transplant recipients (KTR). Focusing on modifiable CVD risk factors is key to decreasing CVD-related…
2015 American Transplant Congress
In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury
K. Famulski,¹ S. Niederhaus,² J. Reeve,¹ J. Bromberg,² P. Halloran.¹
¹University of Alberta, Edmonton, Canada; ²University of Marlyland, Baltimore.
Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…
2015 American Transplant Congress
Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response
A. Salama,^1,2 G. Couvrat-Desvergnes,¹ M. Lorent,^1,3 G. Evanno,¹ L. Le Berre,¹ P. Hruba,⁴ P. Vesely,⁵ P. Guerif,¹ A. Nicot,¹ J.-M. Bach,⁶ Y. Foucher,^1,3 S. Brouard,¹ S. Castagnet,⁷ O. Viklicky,⁴ M. Giral,¹ J. Harb,¹ S. Jean-Paul.¹
¹INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; ²Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; ³EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; ⁴Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; ⁵Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; ⁶IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; ⁷EFS Pays de la Loire, Nantes, France.
Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
2015 American Transplant Congress
Pretransplant Hepatitis B Viral Infection Increased Risk of Death After Kidney Transplantation
J. Lee,¹ J.-H. Cho,² J. An,³ C.-D. Kim,² C. Ahn,⁴ I. Jung,³ D. Han, C. Lim,³ Y. Kim,⁴ Y. Kim, J. Lee.³
¹Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Republic of Korea; ²Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea; ³Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea; ⁴Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; ⁵Surgery, Ulsan University Seoul Asan Medical Center, Seoul, Republic of Korea.
Clinical outcomes have not been well evaluated in kidney transplant recipients (KTRs) with hepatitis B virus (HBV). Here, we aimed to investigate the recent posttransplant…
2015 American Transplant Congress
Risk of End-Stage Renal Disease After Living Donor Liver Transplantation: Overall Incidence and Comparisons to Deceased Donor Recipients
D. Goldberg,¹ R. Ruebner,² P. Abt.³
¹Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; ²Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA; ³Department of Surgery, University of Pennsylvania, Philadelphia, PA.
Introduction: Since initiation of MELD-based allocation for liver transplants, the risk of end-stage renal disease (ESRD) post-liver transplantation has increased. Recent US data demonstrated comparable,…
2015 American Transplant Congress
Safer and More Effective Treatment of Acute Postoperative Pain in Living Liver Donors
D. Ladner,¹ R. Fisher,² J. Guarrera,³ E. Pomfret,⁴ M. Simpson,⁴ A. Daud,⁵ T. Curtis,⁵ E. Reyes,⁵ A. Skaro,¹ D. Woods.⁵
¹Northwestern University, Chicago, IL; ²Virginia Commonwealth University, Richmond, VA; ³Columbia University, New York, NY; ⁴Lahey Clinic, Boston, MA; ⁵CHS, Northwestern University, Chicago, IL.
BACKGROUND: As part of Adult-to-Adult Living Donor Liver Transplant Cohort Study (A2ALL), donors were found to experience significant pain post donation, and more than half…
2015 American Transplant Congress
Immunologic Long-Term Outcome of Living Kidney Transplantation Depending On the Donor-Recipient Relationship
D. Khadzhynov, F. Halleck, D. Schmidt, S. Kreimer, K. Budde, O. Staeck.
Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany.
Background. Only few data is available about long-term immunologic outcomes of living kidney transplantation (KTx) depending on the donor-recepient relationship.Patients and methods. This single center…
2015 American Transplant Congress
Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
K. Omoto,¹ D. Toki,¹ M. Okumi,¹ T. Shimizu,¹ H. Ishida,¹ K. Honda,² J. Koike,³ K. Tanabe.¹
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Department of Pathology, St. Marianna University, School of Medicine, Kawasaki, Japan.
OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…