Am J Transplant, Volume 5, Suppl 3 Archives - Page 59 of 170 - ATC Abstracts

2015 American Transplant Congress
Trends in Transplant Patient Safety Situation Reporting
T. Daly,¹ H. Neil,² D. Stewart,² S. Tlusty,² A. Harper,² D. Marshman,³ M. Green.⁴
¹NY-Presbyterian Hosp., New York, NY; ²UNOS, Richmond, VA; ³LifeNet Health, Roanoke, VA; ⁴Children's Hosp. of Pittsburgh, Pittsburgh, PA.
Background: The OPTN Operations & Safety Committee is charged with reviewing aggregated, de-identified safety situation data reported through both the UNet Improving Patient Safety (IPS)…
2015 American Transplant Congress
DNA Methytransferase 1 Inhibition Potently Suppresses T Cell Cycle Progression Through Demethylation of the Key Cell Cycle Inhibitors p15, p16, p21 and p27
T. Ma, Y. Pei, R. Tao.
Department of Hepatobiliary-Pancreatic Surgery, Zhejiang Provincial Peoples' Hospital, Hangzhou, Zhejiang Province, China.
Background: Epigenetic mechanisms like acetylation and methylation have been gradually appreciated to play a critical role in the generation and function of various immune cells.…
2015 American Transplant Congress
A Novel Post-Transplant High-Dose Cyclophosphamide-Based Regimen to Promote Immune Tolerance After VCA
G. Furtmüller,¹ M. Fryer,¹ B. Oh,¹ S. Ganguly,² J. Izzi,³ D. Cooney,¹ G. Raimondi,¹ W. Lee,¹ L. Luznik,² G. Brandacher.¹
¹Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ²Immunology - Sydney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD; ³Department of Research Animal Resources, Johns Hopkins University, Baltimore, MD.
Background: VCA has become a viable treatment option for devastating tissue defects. However, the life-long need of immunosuppressive medications curtails the wider use of VCA.…
2015 American Transplant Congress
Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection
A. Lichvar,¹ D. Deen,² H. Johnson,¹ J. Bonner,³ G. Bond,⁴ G. Costa,⁴ R. Cruz,⁴ K. Abu-Elmagd,⁵ R. Venkataramanan.^6,7
¹Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA; ²Department of Pharmacy, Memorial University Medical Center, Savannah, GA; ³Northern Institute for Cancer Research at Newcastle University, Tyne and Wear, United Kingdom; ⁴Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; ⁵Center for Gut Rehabilitation and Transplantation, Cleveland Clinic, Cleveland, OH; ⁶Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; ⁷Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…
2015 American Transplant Congress
Responsiveness to Rituximab, Plasmapheresis and Intravenous Immunoglobulins in Antibody Mediated Rejections After Kidney and Pancreas – Kidney Transplantation
E. Minué,¹ L. León,¹ P. Uva,¹ A. Dotta,¹ J. Walther,¹ O. Casanova,¹ F. Togniolo,¹ O. Guardia,¹ M. Rial,¹ E. Chuluyan,² D. Casadei.¹
¹Instituto de Nefrologia, Nephrology, Buenos Aires, Argentina; ²CEFYBO, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina.
The antibody-mediated rejection (AMR) has become clinically critical because this form of rejection is usually unresponsive to conventional anti-rejection therapy. Therefore, it has been recognized…
2015 American Transplant Congress
Social Support After Heart Transplant
E. Stimpson, T. Kao, L. Kim, S. Morrison, J. Patel, M. Kittleson, F. Liou, S. Siddiqui, J. Yabuno, L. Czer, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Social support of patients awaiting heart transplant is mandatory to secure acceptable outcomes after heart transplantation. The types of social support that we have…
2015 American Transplant Congress
Diverticulitis in Immunosuppressed Patients – A Fatal Outcome Requiring a New Approach?
A. Brandl, T. Kratzer, E. Braunwarth, S. Weiss, M. Maglione, S. Schneeberger, R. Kafka-Ritsch.
Visceral, Transplant and Thoracic Surgery, Medical University, Innsbruck, Austria.
PurposeThe purpose of this study was to evaluate in-hospital mortality and morbidity associated with diverticulitis in immunosuppressed patients compared to non-immunosuppressed patients, and to identify…
2015 American Transplant Congress
MiR-26a Regulates Mouse Hepatocyte Proliferation By Directly Targeting Their 3′ Untranslated Region of CCNE2/CCND2
J. Zhou, X. Yuan, W. Ju, X. Jiao, X. Wang, M. Han, D. Wang, X. Zhu, X. He.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Objectives: The deficiency of liver regeneration needs to be addressed in the fields of liver surgery, split liver transplantation and living donor liver transplantation. Researches…
2015 American Transplant Congress
Liver Versus Kidney. A Functional Study on Pancreatic Islet Implantation Sites
T. Corsello,¹ G. Curcuru,² D. Zorzi,³ M. Montalbano,¹ B. Carr,¹ L. Cicalese,¹ C. Rastellini.¹
¹Surgery, UTMB, Galveston, TX; ²Bioingegneria, Univ. of Palermo, Palermo, Sicilia, Italy; ³Surgical Oncology, MD Anderson, Houston, TX.
Background: In the clinical setting, liver is the site currently used for pancreatic islet transplantation (ITX). However, it has been shown that over 50% of…
2015 American Transplant Congress
Liver Allografts from Living Donors Demonstrate High Expression of Hepatic Functional Genes Compared With Deceased Donors
R. Gehrau,¹ J. Suh,¹ K. Brayman,¹ S. Rasmussen,¹ C. Dumur,² V. Mas,¹ D. Maluf.¹
¹Surgery, UVA, Charlottesville, VA; ²Pathology, VCU, Richmond, VA.
Background: Donor shortage motivated alternative practices including living donor liver transplantation (LTx). This study aimed to identify molecular profiles and characteristics in living donor versus…