ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1

    D. Chen, J. Chen, W. Peng.

    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Key Laboratory of Nephropathy, Zhejiang Province; Kidney Disease Immunology Laboratory, The Third Grade Laboratory, State Administration of Traditional Chinese.

    ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…
  • 2015 American Transplant Congress

    Controlled DCD Pancreas Transplantation : A Single Centre Experience

    M. Voskuil, S. Mittal, A. Muthusamy, J. Gilbert, S. Sinha, I. Quiroga, S. Reddy, P. Friend, E. Sharples, A. Vaidya, R. Ploeg.

    Oxford Transplant Centre, Oxford University, Oxford, United Kingdom.

    Background: The use of DCD pancreata are gaining popularity in the UK. Isolated pancreas transplantation (IP) is known to have inferior outcomes in comparison to…
  • 2015 American Transplant Congress

    HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression

    M. Askar,1 N. Elfadawy,1,2 S. Flechner,1 K. Abu-Elmagd,1 J. Fung,1 J. Schold.1

    1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.

    The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…
  • 2015 American Transplant Congress

    Transplantation of Neonatal En-Bloc Kidneys: Do They Grow and Are They Subject to Hyperfiltration Injury?

    J. Woloszyn, C. Santhanakrishnan, C. Troppmann, A. DeMattos, B. Gallay, J. McVicar, J. Sageshima, R. Perez.

    UC Davis Transplant Center, Sacramento, CA.

    Importance:Neonatal Intensive Care Unit (NICU) kidney donation is rare but a potentially significant kidney source. Concerns with using these small kidneys include the risk for…
  • 2015 American Transplant Congress

    Renal Outcomes of Cross Match Positive Simultaneous Liver Kidney (SLK) Transplant Recipients Compared to Cross Match Positive Kidney Allograft Recipients

    S. Vaishnav,1 T. Taber,1 W. Goggins,2 S. Nagaraju,2 J. Fridell,2 A. Sharfuddin,1 M. Yaqub,1 D. Mishler,1 M. Mujtaba.1

    1IUSM, IU Health, Indianapolis, IN; 2Surgery, Transplant, Indiana University School of Medicine, Indianapolis, IN.

    The protective role of liver in cross-match(XM) positive SLK recipients and its impact on the incidence of renal antibody mediated rejection (AMR) is unclear.A retrospective…
  • 2015 American Transplant Congress

    CN Inhibition (But Not mTOR Inhibition) of a Novel CD8+ T Cell Regulatory Mechanism Results in Higher Alloantibody Posttransplant

    J. Zimmerer, S. Elzein, C. Wright, G. Bumgardner.

    Department of Surgery, CTC, The Ohio State University Wexner Medical Center, Columbus, OH.

    MTOR inhibitors [mTORi; Rapamycin, (Rapa)] and calcineurin inhibitors [CNi; Tacrolimus (Tac)] are immunosuppressive drugs commonly used to suppress the rejection of transplanted organs and tissues.…
  • 2015 American Transplant Congress

    Impact of Donor Specific Antibodies in the Older Kidney Transplant Recipient

    S. Patel, J. Loucks-DeVos, R. Knight, S. Kuten, L. Gaber, A. Gaber.

    Houston Methodist Hospital, Houston.

    Recent evidence suggests that renal transplant recipients (RTR) with both rejection and donor specific antibodies (DSA) are at high risk of graft loss. Concurrently, the…
  • 2015 American Transplant Congress

    National Transplantation Pregnancy Registry: Cholestasis of Pregnancy in Liver Transplant Recipients

    M. Moritz,1,2 L. Coscia,2 S. Constantinescu,3 D. Armenti.2

    1Lehigh Valley Health Network, Allentown; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Temple University School of Medicine, Philadelphia.

    Cholestasis of pregnancy (COP) occurs in approximately 1% of pregnancies and is associated with increased risk of premature delivery. The purpose of this study was…
  • 2015 American Transplant Congress

    Outcomes of ABO Incompatible Kidney Transplantation in Children

    J. Stojanovic,1 A. Adamusiak,2 A. Waters,1 D. Bockenhauer,1 N. Kessaris,2 C. Barton,3 H. Jones,3 J. Taylor,3 S. Marks,1 N. Mamode.2

    1Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom; 2Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; 3Department of Paediatric Nephrology, Evelina London Children's Hospital, London, United Kingdom.

    Purpose: ABO blood group incompatible transplantation (ABOi) has become increasingly common over the last decade, in part due to a shortage of suitable deceased donor…
  • 2015 American Transplant Congress

    The Gut Microbiota Regulates Murine Cardiac Transplant Outcome

    C. Brinkman,1 L. Hittle,1 E. Mongodin,1 W. Fricke,2 J. Bromberg.1

    1University of Maryland, Baltimore, MD; 2University of Hohenheim, Stuttgart, Germany.

    Hypothesis: The gut microbiota regulates systemic immunity. Different characteristics of the microbiota can be defined that have pro- or anti-inflammatory effects. We tested the hypothesis…
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