2015 American Transplant Congress
"In-House" Controlled Oxygenated Rewarming After Initial Static Cold Storage: First Clinical Application in Marginal Donor Livers
IntroductionControlled oxygenated rewarming of cold stored livers by machine perfusion demonstrated a strong protective effect in preclinical studies. Here we report on the first clinical…2015 American Transplant Congress
AAV-Mediated TIMP-1 Gene Therapy Ameliorates Hepatic Ischemia/Reperfusion Injury
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…2015 American Transplant Congress
Can MitoQ Improve Renal and Mitochondrial Function Following Cold Storage and Transplantation?
The overall goal of this study is to further evaluate the effectiveness of a potential new therapy designed to minimize damage during cold preservation, increase…2015 American Transplant Congress
A Single Center Comparison of Various BK Viremia Elimination Protocols
Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.
Aim BK infection remains a significant complication post kidney transplantation. Best practices in BK management have evolved over time. The purpose of the study was…2015 American Transplant Congress
hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome
Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…2015 American Transplant Congress
Incorporating Markers of Donor Organ Intrinsic Biology Into Donor Quality Evaluation
UVA, Charlottesville, VA; Northwestern University, Chicago, IL; VCU, Richmond, VA.
Background. We aimed to identify a reliable composite scoring system (clinical / biological) to evalute organ quality and predict outcomes post-kidney transplantation (KT).Methods. 233 deceased…2015 American Transplant Congress
Perioperative Bacterial Colonization and Postoperative Urinary Tract Infection in Kidney Transplant Recipients
Background. Urinary tract infection (UTI) is the most common infection after kidney transplantation, and one of the source of the infection is thought to be…2015 American Transplant Congress
The Differential Effect of HLA-DQ Mismatching on Renal Allograft Survival in Zero HLA-A,B,DR Mismatched Deceased Donor Transplants
1University of Florida, Gainesville; 2University of Kansas, Kansas City.
The role of HLA-DQ matching in renal graft survival is not well understood and difficult to interpret in the presence of other HLA antigen mismatches.…2015 American Transplant Congress
The Impact of Microcirculation Inflammation in Predicting Treatment Response for Late Onset Antibody Mediated Rejection
BackgroundThere have been marked advances of immunosuppression. However, management of late onset antibody-mediated rejection (AMR) after 6 months is still challenging. Despite important diagnostic and…2015 American Transplant Congress
Outcomes of Treatment of Late Antibody-Mediated Rejection in Primary Renal Transplant Recipients – A Single Center Experience
Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.
Background: Successful reversal of early post-transplant antibody mediated rejection (AMR) is well documented, but data on the results of treatment of late AMR are lacking.…
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