Am J Transplant, Volume 5, Suppl 3 Archives - Page 56 of 170 - ATC Abstracts

2015 American Transplant Congress
HLA Broad Antigen and Eplet Mismatches in Determining the Risk of Acute Rejection After Kidney Transplantation
H. Do Nguyen,¹ W. Lim,^1,2 J. Chapman,³ J. Craig,^3,4 G. Wong.^3,4
¹School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia; ²Renal Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia; ³Nephrology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia; ⁴School of Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Aim: To determine the clinical relevance of HLA-ABDR broad antigen and eplet matching for predicting acute rejection after kidney transplantation.Background: HLAMatchmaker determines structurally HLA compatibility…
2015 American Transplant Congress
Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants
J. Leventhal,¹ M. Elliott,² E. Yolcu,² L. Bozulic,³ D. Tollerud,³ J. Mathew,¹ I. Konieczna,¹ M. Ison,¹ M. Badder,³ M. Abecassis,¹ J. Miller,¹ L. Gallon,¹ S. Ildstad.³
¹Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; ²University of Louisville, Institute for Cellular Therapeutics, Louisville, KY; ³Regenerex, LLC, Louisville, KY.
We report the long-term results from a reduced-intensity nonmyeloablative conditioning approach to establish high levels of donor chimerism without graft-versus-host disease (GVHD) in mismatched related…
2015 American Transplant Congress
Recreational and Lifestyle Infection Risks in Transplant Recipients
R. Avery,¹ D. Ostrander,¹ S. Shoham,¹ S. Alp,² N. Lu,¹ C. Cave,¹ E. Kraus,³ K. Marr.¹
¹Infectious Disease, Johns Hopkins, Baltimore, MD; ²Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; ³Nephrology, Johns Hopkins, Baltimore, MD.
Background: Counseling is commonly provided to transplant candidates and recipients concerning “strategies for safer living”, including ways to minimize infection risk.Methods: Patients enrolled in a…
2015 American Transplant Congress
Regional Efficiency in Deceased Donor Utilization for Kidney Transplantation
K. Schnier,¹ N. Turgeon.²
¹School of Social Sciences, Humanities and Arts, University of California, Merced, Merced, CA; ²Department of Surgery, Emory University School of Medicine, Atlanta, GA.
Background: There currently exists regional variation in the supply of deceased donors as well as the demand for kidney transplantation. This has stimulated a growing…
2015 American Transplant Congress
Avoiding Futility in Simultaneous Liver-Kidney Transplantation (SLKT): Analysis of 331 Consecutively Listed Patients
K. Lunsford, A. Bodzin, D. Reino, A. Zarrinpar, F. Kaldas, H. Gritsch, J. Veale, G. Lipshutz, D. Farmer, G. Danovitch, H. Yersiz, J. Hiatt, R. Busuttil, V. Agopian.
Departments of Surgery, Urology, and Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Without well-established listing guidelines for SLKT, MELD prioritization of liver recipients with renal dysfunction potentially risks scarce renal allografts. We sought to evaluate short-term predictors…
2015 American Transplant Congress
Heart Transplant for Amyloid Patients in the Current Era of Bortezomib
J. Patel, R. Vescio, M. Kittleson, S. Siddiqui, F. Liou, J. Yabuno, L. Piponniau, B. Kearney, M. Hamilton, L. Czer, J. Kobashigawa.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid have been viewed with reluctance to proceed with heart transplant. AL amyloid in particular…
2015 American Transplant Congress
Microvascular Inflammation in Early Protocol Biopsies of Renal Allografts in Cases of Chronic Active Antibody-Mediated Rejection
T. Tsuji,¹ M. Yanai,¹ H. Itami,¹ Y. Ishii,¹ M. Akimoto,¹ N. Fukuzawa,² H. Harada,² Y. Fukasawa.¹
¹Demartment of Pathology, Sapporo City General Hospital, Sapporo, Japan; ²Department of Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan.
Aim:Chronic active antibody-mediated rejection (chronic ABMR) is one important cause of late-stage renal allograft loss. However, few reports have used protocol biopsy to observe changes…
2015 American Transplant Congress
Determinants and Sequelae of Hepatic Artery Thrombosis After Liver Transplantation: A Registry Study of Recipient Diagnosis and Coagulopathy
J. Garonzik Wang,¹ M. Doyle,¹ K. Collins,¹ J. Lowell,¹ Y. Lin,¹ S. Shenoy,¹ J. Wellen,¹ W. Chapman,¹ D. Segev.²
¹Washington University, Barnes Jewish Hospital, Saint Louis, MO; ²Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD.
Hepatic artery thrombosis (HAT) is a dreaded complication following liver transplantation. Despite improvements in technique and procurement, HAT still occurs in approximately 2-5% of recipients.…
2015 American Transplant Congress
Results of Broader Sharing of Young Pediatric Donor Lungs and Priority Allocation System for Young Pediatric Lung Candidates
W. Cherikh,¹ A. Wilk,¹ L. Edwards,¹ G. Visner,² Y. Cheng,¹ S. Sweet.³
¹United Network for Organ Sharing, Richmond, VA; ²Boston Children's Hospital, Boston, MA; ³Washington Univ, St. Louis, MO.
Background. Two major changes for allocation of young pediatric (ped) lung (LU) donors and young ped candidates were implemented on 9/12/10. LUs from 0-11 year…
2015 American Transplant Congress
Iron Deficiency Impairs Regulatory T Cell Induction
R. Danger,¹ E. Bonaccorsi-Riani,¹ E. Kodela,¹ H. Collins,² R. Hider,³ M. Martínez-Llordella,¹ A. Sánchez-Fueyo.¹
¹Department of Liver Sciences, Faculty of Life Sciences & Medicine, MRC Transplant Centre, King's College London, London, United Kingdom; ²Department of Immunology, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom; ³Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
In a recent clinical trial of immunosuppression withdrawal in adult liver transplant recipients, operational tolerance was associated with development of a transient lymphocyte infiltration rich…