2015 American Transplant Congress
Comparison of the Clinical Outcome and Surgical Invasiveness for Living Donor Nephrectomy Between Conventional Laparoscopic Surgery and Single-Port Surgery
Urology, Akita University Graduate School of Medicine, Akita, Japan.
INTRODUCTION AND OBJECTIVES:Single-port surgery (SPS) for living donor nephrectomy (LDN) is challenging. Whether SPS is less invasive compared to conventional laparoscopic surgery (CLS) using several…2015 American Transplant Congress
Extracorporeal Life Support: A Rescue Therapy in a Lung Transplantation Program
Purpose: Extracorporeal Life Support (ECLS) is increasingly used as a bridge to lung transplantation (LTx) as well as in the management of severe primary graft…2015 American Transplant Congress
Change in Physical Function Following Kidney Transplantation
Introduction: Improved physical function is associated with increased survival in the general population. Little is known about whether physical function improves following kidney transplant. The…2015 American Transplant Congress
Differences in Reactivity of HLA-Specific Antibodies May Be Explained By Differences in Their Affinities for Selected Epitopes on HLA Proteins
Affinity of IgG immunoglobulins for antigen varies and matures within the evolution of immune responses. Affinity is likely to be different for different epitope-antibody interactions…2015 American Transplant Congress
Gene Expression of Kidney Biopsies Reveals Common Mechanisms of Rejection and a Cluster of Co-Expressed Genes Predictive of Long-term Outcomes
1The Scripps Research Institute, La Jolla; 2Northwestern University, Chicago.
Purpose: Acute rejection (AR) still affects 8-14% of kidney transplants and rates of 10-year graft loss remain unchanged in part due to chronic rejection (CR).…2015 American Transplant Congress
The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance
Transplantation Biology Research Center, Massachusetts General Hospital, Boston, MA.
Background: We have developed a reproducible model for induction of tolerance of all components of VCAs across haploidentical MHC barriers in miniature swine. The purpose…2015 American Transplant Congress
Immunomodulatory Strategies Directed Towards Tolerance of Vascularized Composite Allografts
Background: Achieving tolerance of vascularized composite allografts (VCAs) would improve the risk-to-benefit ratio in patients who undergo this life-enhancing transplant. Kidney co-transplantation along with a…2015 American Transplant Congress
Tissue Engineering Human Kidneys for Costimulation Blockade
1BREONICS, Inc., Watervliet, NY; 2Surgery, University of Utrecht, Utrecht, Netherlands.
Methods for preserving organs have employed hypothermic conditions. At these temperatures metabolism is 4% of normal. Tissue engineering of organs cannot be done without significant…2015 American Transplant Congress
B-Cell Activation in Acute Kidney Injury and Delayed Graft Function
Background:Acute kidney injury (AKI) is a relevant complication after kidney transplantation and also after non-renal solid organ transplantation. Growing evidence points towards an important role…2015 American Transplant Congress
Lessons Learned from the Clinical Use of Normothermic Regional Perfusion (nRP) in Uncontrolled Donation After Circulatory Death (DCD)
The national protocol for the uDCD program restricts donor age < 55 y, no flow period < 30 min and total warm ischemia time (WIT)…
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