Am J Transplant, Volume 5, Suppl 3 Archives - Page 54 of 170 - ATC Abstracts

2015 American Transplant Congress
Screening Recipients of Increased Risk Donor Organs: A Multicenter Study
N. Theodoropoulos,¹ K. Brizendine,² M. Ison.³
¹Infectious Diseases, The Ohio State University, Columbus, OH; ²Infectious Disease, Cleveland Clinic, Cleveland, OH; ³Infectious Diseases/Organ Transplantation, Northwestern University, Chicago, IL.
Purpose: Policy mandates post-transplant (tx) evaluation of recipients of increased risk donor organs (ROIRDO). PHS guidelines recommend that screening include HIV & hepatitis C virus…
2015 American Transplant Congress
Non-Invasive Panel of MicroRNAs Predict Long-Term Outcomes Post-Kidney Transplantation
J. Suh,¹ D. Maluf,¹ H. Cathro,² R. Gehrau,¹ I. McConnell,¹ K. Brayman,¹ C. Dumur,² V. Mas.¹
¹Surgery and Pathology, UVA, Charlottesville, VA; ²VCU, Richmond, VA.
Background. Currently available methods for evaluating kidney graft function post-transplantation (KT) are either ineffective or inaccurate (e.g., serum creatinine) or highly invasive (e.g., biopsies). We…
2015 American Transplant Congress
Changes in Health Related Quality of Life (HRQOL) in Pediatric Liver Transplant (LT) Recipients During Protocolized Immunosuppression Withdrawal (ISW): The iWITH Trial
S. Mohammad,¹ S. Sundaram,² V. Venkat,³ M. Martinez,⁴ J. Lopez,⁵ J. Magee,⁵ E. Alonso,¹ S. Feng.⁶
¹Northwestern U, Chicago; ²U of Colorado, Aurora; ³U of Pittsburgh, Pittsburgh; ⁴Columbia U., New York; ⁵U of Michigan, Ann Arbor; ⁶UCSF, San francisco.
ISW may limit medication-related comorbidities but intensive monitoring and unexpected rejection episodes may compromise HRQOL. We studied longitudinal HRQOL in pediatric LT recipients undergoing ISW…
2015 American Transplant Congress
The Selection Process for Total Artificial Heart
F. Arabia, L. Czer, M. Kittleson, E. Passano, F. Liou, J. Yabuno, H. Henry, D. Chang, F. Esmailian, J. Kobashigawa, J. Moriguchi.
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Heart failure patients with severe biventricular failure who are candidates for heart transplant are considered for Total Artificial Heart (TAH) support. These patients may…
2015 American Transplant Congress
Failure to Account for Critical Candidate Characteristics Significantly Biases Kidney Transplant Center Report Cards Measuring Time to Transplant
L. Kayler,¹ J. Schold.²
¹Surgery, Montefiore Medical Center, Bronx, NY; ²Medicine, Cleveland Clinic, Cleveland, OH.
Kidney transplant rate is proposed to be integrated into the new composite metric to evaluate center performance. Current methods adjust for PRA, blood type, re-transplantation,…
2015 American Transplant Congress
Matching Strategies in Kidney Paired Donation: A 7-Year Analysis of a Multi-Institutional Registry
D. Fumo,^1,2 L. Reece,² S. Stepkowski,¹ V. Kapoor,¹ S. Rees,² J. Kopke,² M. Rees.^1,2
¹University of Toledo Medical Center, Toledo, OH; ²Alliance for Paired Donation, Maumee, OH.
Failure to convert computer-identified possible Kidney Paired Donation (KPD) exchanges into transplants has prevented KPD from reaching its full potential. The purpose of this study…
2015 American Transplant Congress
Negative Effects of Being Obese or Overweight on T Regulatory (Treg) Cell Suppressive Function in Patients Listed for Lung Transplantation (Tx)
T. Akimova,¹ J. Diamond,² D. Wilkes,³ D. Lederer,⁴ J. Christie,² W. Hancock.¹
¹Path & Lab Med, CHOP & UPenn, Philadelphia; ²Pulm, Allergy & Crit Care Med, UPenn, Philadelphia; ³Med, Microbiol & Immunol, Indiana Uni Sch of Med & Thoracic Transplant Prog, Indianapolis; ⁴Medicine, Columbia Uni, New York.
Aim: Obese and overweight patients may be prone to adverse outcomes following lung Tx. We sought to determine the relationship between body mass index (BMI)…
2015 American Transplant Congress
Ex Vivo Expansion With Rapamycin Enhances the Suppressive Function of Regulatory T Cells (Tregs) Isolated from Pediatric Thymus
E. Dijke,^1,2,3 R. Hoeppli,^3,4 T. Ellis,^1,2 J. Pearcey,^1,2 I. Larsen,^1,2 I. Rebeyka,^1,2 D. Ross,^1,2 M. Levings,^3,4 L. West.^1,2,3
¹University of Alberta, Edmonton, AB, Canada; ²Alberta Transplant Institute, Edmonton, AB, Canada; ³Canadian National Transplant Research Program, Edmonton/Vancouver, AB/BC, Canada; ⁴University of British Columbia, Vancouver, BC, Canada.
INTRODUCTION: Treg-based cellular therapy to suppress graft-directed immunity could reduce the need for life-long immunosuppressive drugs. Challenges include isolation and expansion of pure Tregs to…
2015 American Transplant Congress
Rejection of an Allograft Through Non-MHC Antigens Does Not Translate to the Rejection of a Different Allograft from the Same Donor in Mixed Chimeras
K. Shinoda,¹ C. Chase,¹ P. Russell,¹ J. Madsen,¹ R. Colvin,² A. Alessandrini.¹
¹Transplant Center, Massachusetts General Hospital, Boston, MA; ²Pathology, Massachusetts General Hospital, Boston, MA.
We previously showed that tolerance, induced by mixed chimerism in mice, is antigen-specific: tolerance of heart and skin allografts is dependent on Foxp3+ cells that…
2015 American Transplant Congress
Risk of HLA Antibody Sensitization in Pediatric Heart Failure Patients Pre/Post Berlin VAD Procedure and Pre/Post Heart Transplantation
R. Kerman, P. Jindra, A. Jeewa, S. Burki, C. Fraser, I. Adachi.
Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.
The Berlin Heart Excor Ventricular Assist Device (Berlin VAD) was designed for use in children with heart failure. The Berlin VAD has allowed for successful…