2015 American Transplant Congress
Development of a Targeted Genetic Renal Disease Panel With NexGen Sequencing for Unbiased Testing of Living Kidney Donors for Genetic Kidney Disease
Recent studies indicate that living donors biologically related to their transplant recipient may be at higher risk of ESRD compared to unrelated donors, possibly secondary…2015 American Transplant Congress
Pretransplant Elevated Plasma Fibrinogen Level Is Associated With Tumor Recurrence and Poor Prognosis in Hepatocellular Carcinoma Patients After Liver Transplantation
Background and Objective: Elevated plasma fibrinogen (FBG) level is associated with tumor progression and poor patient outcomes in several cancers. The aim of this study…2015 American Transplant Congress
In Vitro Evidence That CTLA4Ig Attenuates Recall Alloantibody Responses
Background: CTLA4Ig is an agonist that blocks CD28-B7 costimulation, downregulating T cell immunity, but also appears to negate T cell-dependent B cell activation, thus inhibiting…2015 American Transplant Congress
Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival
Aim: Current strategies for management of VCA recipients are adapted from solid organ transplant protocols, and almost universally employ induction therapy followed by maintenance triple…2015 American Transplant Congress
CD3+CD4+ROR gamma t+ TH17 Cells Do Not Play a Critical Role in Islet Allograft Rejection
Medicine, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA.
We have developed a “color-coded” adoptive transfer model for T cell subset identification that enables serial analysis of islet allograft infiltrating yellow induced regulatory T…2015 American Transplant Congress
Association of Pulmonary Hypertension at Kidney Transplant Evaluation and Subsequent Outcomes Following Transplantation
Background - Pulmonary hypertension (PH) is common among patients with end stage renal disease (ESRD) who depend on dialysis before transplant, and PH is associated…2015 American Transplant Congress
Everolimus Initiation Immediately After Liver Transplantation: A Single-Center Experience
University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
BackgroundClinical trials in liver transplant (LTX) patients with randomization on day 30 to everolimus (EVR) show a benefit in renal function compared to calcineurin inhibitor…2015 American Transplant Congress
Elevated Cancer Risk Among US Pediatric Solid Organ Transplant Recipients
Among pediatric transplant recipients, the effects of transplantation and immunosuppression on cancer risk may be unique from those observed in the adult transplant population. No…2015 American Transplant Congress
Donor and Recipient Pretransplant Polyoma BK Serostatus: Relationship to BK-Viremia After Renal Transplantation
Surgery, Albany Medical College, Albany, NY.
Background:Polyoma virus BK nephropathy is a serious complication after renal transplantation and is associated with a significant risk of graft loss and dysfunction. This study…2015 American Transplant Congress
Patient Outcomes After Listing for Kidney Alone Transplantation in Potential Recipients Aged Over 70 Years
BackgroundLow likelihood of listing and subsequent deceased donor transplantation has previously been reported for the elderly with additional concerns about patient frailty, morbidity and mortality…
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