2015 American Transplant Congress
Dermatology Is an Essential Part of Transplant Care: Report of a Two-Year Experience from a Transplant Dermatology Center
Background: It is well-documented that patients who have undergone organ transplantation have a higher incidence of new skin cancers and that this risk is magnified…2015 American Transplant Congress
Correlation of Longitudinal Gene-Expression Profiling Score to Cytomegalovirus Infection: Results from the Outcomes AlloMap® Registry
Purpose: Cytomegalovirus (CMV) infection has been implicated in the pathogenesis of allograft rejection, which is reflected by high gene-expression profiling (GEP) scores. In the IMAGE…2015 American Transplant Congress
Safety and Outcome of Ganciclovir-Resistant CMV Treated With Foscarnet: A Single Center Retrospective Study
Background: Infection with cytomegalovirus (CMV) is an important cause of morbidity and mortality following solid organ transplantation (SOT). Resistance can rarely develop via mutations in…2015 American Transplant Congress
A Cross-Organ Tissue Gene Expression Immune Signature Predates Chronicity
Transplantation Surgery, UC San Francisco, San Francisco, CA.
Purpose Meta-analysis of 796 microarrays led to the discovery of 11 over-expressed genes (BASP1, CD6, CXCL9, CXCL10, INPP5D, ISG20, LCK, NKG7, PSMB9, RUNX3, and TAP1)…2015 American Transplant Congress
Controlled DCD Pancreas Transplantation : A Single Centre Experience
Oxford Transplant Centre, Oxford University, Oxford, United Kingdom.
Background: The use of DCD pancreata are gaining popularity in the UK. Isolated pancreas transplantation (IP) is known to have inferior outcomes in comparison to…2015 American Transplant Congress
HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression
1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.
The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…2015 American Transplant Congress
Transplantation of Neonatal En-Bloc Kidneys: Do They Grow and Are They Subject to Hyperfiltration Injury?
UC Davis Transplant Center, Sacramento, CA.
Importance:Neonatal Intensive Care Unit (NICU) kidney donation is rare but a potentially significant kidney source. Concerns with using these small kidneys include the risk for…2015 American Transplant Congress
Renal Outcomes of Cross Match Positive Simultaneous Liver Kidney (SLK) Transplant Recipients Compared to Cross Match Positive Kidney Allograft Recipients
The protective role of liver in cross-match(XM) positive SLK recipients and its impact on the incidence of renal antibody mediated rejection (AMR) is unclear.A retrospective…2015 American Transplant Congress
CN Inhibition (But Not mTOR Inhibition) of a Novel CD8+ T Cell Regulatory Mechanism Results in Higher Alloantibody Posttransplant
Department of Surgery, CTC, The Ohio State University Wexner Medical Center, Columbus, OH.
MTOR inhibitors [mTORi; Rapamycin, (Rapa)] and calcineurin inhibitors [CNi; Tacrolimus (Tac)] are immunosuppressive drugs commonly used to suppress the rejection of transplanted organs and tissues.…2015 American Transplant Congress
Impact of Donor Specific Antibodies in the Older Kidney Transplant Recipient
Houston Methodist Hospital, Houston.
Recent evidence suggests that renal transplant recipients (RTR) with both rejection and donor specific antibodies (DSA) are at high risk of graft loss. Concurrently, the…
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