ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Preservation Solution Impacts Short- and Long-Term Survival in Orthotopic Heart Transplant Recipients

    C. Lewis,1 S. Jayarajan,1 S. Taghavi,1 S. Kadakia,1 V. Ambur,1 A. Shiose,3 G. Wheatley,3 L. Kaiser,2 T. Guy,3 Y. Toyoda.3

    1Department of Surgery, Temple University Hospital, Philadelphia, PA; 2Division of Thoracic Surgery, Temple University Hospital, Philadelphia, PA; 3Division of Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA.

    Objectives: To examine the effect of three commonly used preservation solutions on short- and long-term survival after orthotopic heart transplantation (OHT) using a large national…
  • 2015 American Transplant Congress

    The Economic Impact of Nonimmune Complications in Contemporary Kidney Transplantation

    K. Lentine,1 M. Schnitzler,1 D. Axelrod,2 D. Segev,3 D. Brennan,4 J. Tuttle-Newhall,1 H. Xiao,1 L. Kucirka,3 V. Dharnidharka.4

    1Saint Louis Univ, St Louis; 2Dartmouth, Lebanon; 3Johns Hopkins, Baltimore; 4Washington Univ, St. Louis.

    The clinical burden and economic impacts of nonimmune complications after kidney transplant (KT) are incompletely defined.We examined United States Renal System Registry Data for Medicare-insured…
  • 2015 American Transplant Congress

    Initial Experience With a Tailor-Made Simulation and Navigation Program Using a 3D Printer Model of Kidney Transplantation Surgery

    M. Kusaka,1 M. Sugimoto,2 N. Fukami,1 H. Sasaki,1 M. Takenaka,1 T. Ito,3 T. Kenmochi,3 R. Shiroki,1 K. Hoshinaga.1

    1Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan; 2Department of Gastroenterology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 3Department of Organ Transplant Surgery, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan.

    Introduction: Three-dimensional (3D) printing systems allow for the creation of surgical models mimicking real tissue. We developed a kidney graft and pelvic cavity replica as…
  • 2015 American Transplant Congress

    Normothermic Machine Perfusion (NMP) on Discarded Human Livers: The First Model in the US

    Q. Liu, A. Nassar, G. Iuppa, D. Urcuyo-Llanes, D. Sexton, T. Okamoto, T. Uso, A. Bennett, W. Baldwin, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini.

    Cleveland Clinic, Cleveland, OH.

    The benefit of NMP preservation has been reported in a number of animal studies. Herein we describe safety, feasibility and effectiveness of NMP on discarded…
  • 2015 American Transplant Congress

    Stimulating Protease Inhibitor 9 Expression By Human Regulatory T Cells Improve Homeostasis

    P. Lukyanchykov, Z. Solhjou, A. Radwan, L. Riella, A. Chandraker, R. Abdi, J. Azzi.

    Renal/ Transplantation Research Center, Brigham and Women's Hospital, Boston, MA.

    In this study, we show for the first time the key role of a protease inhibitor PI9 in human regulatory T cells (Tregs) homeostasis. Recent…
  • 2015 American Transplant Congress

    Cytotoxic CD8 T Cell Recognition of Acquired, Intact MHC Alloantigen On Host Dendritic Cells Promotes Acute Allograft Rejection

    J. Ali, S. Harper, M. Negus, E. Bolton, J. Bradley, G. Pettigrew.

    University of Cambridge, Cambridge, United Kingdom.

    IntroductionAlthough there is increasing evidence that recipient DCs can acquire intact MHC class I by trogocytosis from parenchymal cells, the functional relevance of the 'semi-direct'…
  • 2015 American Transplant Congress

    Natural History of Anti- Human Leukocyte Antigen Antibodies After Hear Transplant

    J. Kobashigawa, M. Kittleson, F. Liou, S. Siddiqui, R. Shiozaki, L. Piponniau, D. Geft, M. Hamilton, L. Czer, N. Reinsmoen, J. Patel.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: The natural history of the production of circulating antibodies has not yet been clearly established. Recent technology has allowed for the improved detection of…
  • 2015 American Transplant Congress

    Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection

    M. Rabant,1,2 L. Amrouche,2,3 X. Lebreton,3 F. Aulagnon,3 A. Benon,2 V. Sauvaget,2 R. Bonifay,2 L. Morin,3 A. Scemla,3 M. Delville,3 F. Martinez,3 M. Timsit,4 J. Duong Van Huyen,1 C. Legendre,3 F. Terzi,2 D. Anglicheau.2,3

    1Pathology Department, Necker Hospital, Paris, France; 2INSERM U1151, Necker Hospital, Paris, France; 3Kidney Transplant Center, Necker Hospital, Paris, France; 4Urology Department, Necker Hospital, Paris, France.

    The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…
  • 2015 American Transplant Congress

    The Impact of a Desensitization Protocol Using Plasmapheresis and Intravenous Immunoglobulin On Graft Outcome in Kidney Recipients With Donor Specific Anti-HLA Antibodies

    J. Junqueira, T. Leite, A. Junqueira, R. Esmeraldo.

    Hospital Geral de Fortaleza, Fortaleza, Brazil.

    Introduction: Kidney transplantation in patients with donor-specific anti-HLA antibodies (DSA) has been associated with a worse prognosis. The high cost, infectious complications and conflicting results…
  • 2015 American Transplant Congress

    Robotic Kidney Transplantation in Obese Recipients Can Lead to Superior Outcomes in Terms of Wound Infection and Graft Survival

    I. Tzvetanov, G. D'Amico, G. Georgiev, P. Giulianotti, H. Jeon, R. Garcia-Roca, J. Oberholzer, E. Benedetti.

    Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.

    IntroductionTraditionally kidney transplantation (KT) in obese recipients has been associated with high rates of surgical site infections (SSI). We hypothesize that robotic kidney transplantation (RKT)…
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