2015 American Transplant Congress
Financial Impact of an Advanced Liver Disease Service on a Tertiary Health System
Regional disparities in liver transplantation motivated revision of national organ-sharing policies towards critically ill patients. Liver transplantation of high MELD patients incorporates significant institutional commitment…2015 American Transplant Congress
Human CD8+TCR– Facilitating Cells Enhance HSC Engraftment In Vivo and Promote HSC Survival In Vitro
CD8+/TCR- facilitating cells (FC) in mouse BM significantly enhance engraftment of hematopoietic stem cells (HSC) in syngeneic and allogeneic recipients. Human FC phenotype and mechanism…2015 American Transplant Congress
Targeted Rapamycin Nanotherapy Dampens Memory T Cell Function
Memory T cells (Tm) are difficult to control post-transplantation and account for early rejection episodes. Additionally, therapies exerting local immunosuppression by targeting an allograft, while…2015 American Transplant Congress
Prevalence and Clinical Outcomes Associated With Vancomycin-Resistant Enterococcal Colonization Or Infection After Small Intestinal Transplantation
BACKGROUND: Vancomycin-resistant enterococcal (VRE) infections cause significant morbidity and mortality amongst SOT recipients. However, little is known about the relevance of VRE in small intestinal…2015 American Transplant Congress
Evaluating the Benefits of Everolimus on Cardiac Allograft Vasculopathy: Further Evidence from Results of Imputations for Missing IVUS Data from A2310 Study
Purpose: A2310 IVUS study showed that everolimus (EVR) provides cardiac allograft vasculopathy (CAV) benefit compared to mycophenolate mofetil (MMF) by assessing the mean change in…2015 American Transplant Congress
The Outcome of Carbapenemase-Producing Enterobacteriaceae (CPE) Infection in Adult Solid Organ Transplant Population at a University Teaching Hospital
Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.
BACKGROUND:Over the last decade CPE infection has been reported globally and is now endemic in healthcare facilities in many countries. There has been no report…2015 American Transplant Congress
Pancreatic Islet Survival Under Confinement
UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.
The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…2015 American Transplant Congress
Immune Rejection of iPS Cells Is Triggered By Gamete-Associated Proteins (GAPs)
Induced pluripotent stem (iPS) cells have emerged as a new source for cell based therapies. However, the safety of iPS cells in autologous recipients has…2015 American Transplant Congress
A Randomized Cross-Over Phase 3b Study of the Pharmacokinetics of Once-Daily Extended Release MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus in African-Americans (ASERTAA)
The CYP3A5*1 genotype, highly prevalent in African Americans (AA), commonly necessitates higher tacrolimus (tac) dose requirements and may hinder efforts to obtain therapeutic drug levels.…2015 American Transplant Congress
Histology of Renal Allografts With DGF Provides Limited Prognostic Information
DGF has been shown to be associated with adverse graft outcomes in renal transplantation. However DGF is heterogeneous histologically and the impact of various histological…
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