Am J Transplant, Volume 5, Suppl 3 Archives - Page 38 of 170 - ATC Abstracts

2015 American Transplant Congress
Effectiveness of Neovascularization Surrounding Engrafted Islets by Matrigel With Additional Growth Factors in Intramuscular Islet Transplantation
G. Yoshimatsu,^1,2 N. Sakata,² H. Tsuchiya,² M. Takita,³ M. Levy,³ B. Naziruddin,³ M. Unno.²
¹Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; ²Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan; ³Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.
Introduction: Intramuscular islet transplantation is one of the promising transplant sites because of safety, easy accessibility and less invasive procedure. However the efficacy of the…
2015 American Transplant Congress
Induction of iNOS Expressed Macrophages from Mouse iPS cells That Contribute to Prolong Same iPS Cells-Derived Graft Survival in Allogeneic Recipients
H. Sasaki,¹ H. Wada,² K. Morita,¹ K.-I. Seino,² N. Shinohara.¹
¹Genitourinary Surgery, Hokkaido University, Sapporo, Japan; ²Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.
BACKGROUND: Induced pluripotent stem cells (iPSCs)-technology provides new opportunities in regenerative medicine to generate grafts from donors for transplantation. However, particularly when allogeneic iPSCs are…
2015 American Transplant Congress
Improved Bioavailability and Reduced Dose Requirements of Novel, Once-Daily, MeltDose® Tacrolimus Formulation Tablets (Envarsus® XR) Compared to Twice-Daily Tacrolimus Capsules (Prograf®) in De Novo Kidney Transplantation: Results of a Phase 3 Double-Dummy, Randomized Trial
J. Grinyó,¹ S. Bunnapradist,² S. Mulgaonkar,³ S. Steinberg.⁴
¹University of Barcelona, Catalunya, Barcelona, Spain; ²David Geffen School of Medicine at UCLA, Los Angeles; ³St. Barnabas Medical Center, Livingston; ⁴California Institute of Renal Research, San Diego.
Tacrolimus (tac) is an immunosuppressive drug with a narrow therapeutic range. Adequate trough levels following kidney transplantation (≥6 ng/mL depending on regimen and time post-transplant)…
2015 American Transplant Congress
Increase in Neurologic Determination of Death (NDD) Organ Donation in the Donation After Circulatory Death (DCD) Era. The Ontario Experience
J. Zaltzman,^1,2 J. MacLean,² C. Payne,² E. Paltser,² V. Rao,³ S. Dhanani.^2,4
¹Medicine, Nephrology & Transplant, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; ²Trillium Gift of Life Network, Ontario, Toronto, ON, Canada; ³Cardiovascular Surgery and Multi-Organ Transplant, University Health Network, University of Toronto, Toronto, ON, Canada; ⁴Pediatric Critical Care, Children's Hospital of Eastern Ontario, Univeristy of Ottawa, Ottawa, ON, Canada.
Some jurisdictions have reported a decrease in neurologic determination of death organ donors (NDD) with the implementation of donation after circulatory death (DCD) organ donation.…
2015 American Transplant Congress
The Synergistic Effect of Class II HLA Epitope-Mismatch and Non-Adherence on Acute Rejection and Graft Survival
C. Wiebe,^1,2 T. Nevins,³ W. Robiner,^3,4 W. Thomas,⁵ A. Matas,⁶ P. Nickerson.^1,2,8
¹Medicine, University of Manitoba, Winnipeg, MB, Canada; ²Transplant Immunology, Diagnostic Services of Manitoba, Winnipeg, MB, Canada; ³Pediatrics, University of Minnesota, Minneapolis, MN; ⁴Medicine, University of Minnesota, Minneapolis, MN; ⁵Public Health, University of Minnesota, Minneapolis, MN; ⁶Surgery, University of Minnesota, Minneapolis, MN; ⁷Immunology, University of Manitoba, Winnipeg, MB, Canada.
Predicting long-term outcomes in renal transplant recipients is essential to optimize medical therapy and determine the frequency of post-transplant pathologic and serologic monitoring. Non-adherence and…
2015 American Transplant Congress
Analysis of Causes of Graft Loss Among Kidney Transplant Patients Receiving Tacrolimus Vs Cyclosporine
M. Kamel,¹ M. Posadas Salas,¹ D. Taber,² M. Kadian,¹ M. Salazar,¹ P. Mohan,¹ T. Srinivas.¹
¹Department of Medicine, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC.
Tacrolimus (FK) has surpassed cyclosporine (CYA) as the calcineurin inhibitor (CNI) of choice for the vast majority of kidney transplant (KTX) programs. Yet, CYA continues…
2015 American Transplant Congress
A Joint Survival Longitudinal Approach to Better Assess the Etiological Role of Risk Factors of Kidney Transplant Graft Failure
M.-C. Fournier,^1,2 E. Dantan,¹ Y. Foucher,^1,2 M. Giral.²
¹EA 4275 - SPHERE - Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France; ²INSERM CR1064 Centre pour la Recherche en Transplantation et Immunointervention (CRTI), Institut Transplantation-Urologie-Néphrologie (ITUN), Nantes, France.
Background. Although risk factors of graft failure after renal transplantation have been widely considered, it is difficult to distinguish their etiological role: a direct association…
2015 American Transplant Congress
Split and Living Donor Versus Whole Liver Transplantation for Hepatocellular Carcinoma in Adult Recipients: A Single Center Analysis
O. Boillot, O. Guillaud, J. Dumortier.
Liver Transplant Unit, Edouard Herriot Hospital, lyon, France.
INTRODUCTIONThe use of partial liver grafts in the context of hepatocellular carcinoma (HCC) remains a matter ofdebate because of a supposed higher risk of cancer…
2015 American Transplant Congress
Prehypertension and Abnormal Fasting Glucose Are the Main Factors Associated With Progressive Deterioration of Renal Function in Kidney Donors
J. Arreola-Guerra,¹ M. Arvizu-Hernandez,² R. Correa-Rotter,² L. Morales-Buenrostro,² J. Alberu.¹
¹Transplantation, National Institute of Nutrition and Medical Sciences Salvador Zubirán, Mexico City, Mexico; ²Nephrology and Mineral Metabolism, National Institute of Nutrition and Medical Sciences Salvador Zubirán, Mexico City, Mexico.
Background: For reasons unclarified, some kidney donors (KD) are patients (pts) that throughout its evolution remain with the same renal function (RF) or even continue…
2015 American Transplant Congress
Living Kidney Donation in the Elderly: The United Kingdom Experience
Z. Ahmed,¹ R. Tamburrini,¹ L. Pankhurst,² N. Kessaris,¹ N. Mamode.¹
¹Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; ²Department of Clinicsl Trials and Statistics, NHS Blood and Transplant, Bristol, United Kingdom.
Introduction: The increasing demand for organs has led many institutions to accept elderly patients onto their living donor programmes. However no large UK based datasets…