2015 American Transplant Congress
How Long Is Too Long? The Impact of Bridge Donor Waiting Time on Paired Donation Transplants
1University of Toledo Medical Center, Toledo, OH; 2Alliance for Paired Donation, Maumee, OH.
Non-simultaneous Extended Altruistic Donor (NEAD) chains and bridge donors (BD) are increasingly utilized in the field of Kidney Paired Donation (KPD), but remain controversial due…2015 American Transplant Congress
The Impact of Hypertension, Chronic Pain, and Fatigue on Long-Term Quality of Life After Living Kidney Donation
The rising prevalence of end-stage renal disease and Germany's chronic organ shortage subsequently calls more people upon to consider living kidney donation. The benefits for…2015 American Transplant Congress
C1q Reactivity and IgG Subtypes After HLA Antibody Removal Therapy With Carfilzomib in Thoracic Transplant Recipients
Univ of Pittsburgh, Pittsburgh.
Conventional therapies for antibody removal consisting of plasma exchange with IVIG and Rituximab are partially effective in desensitization protocols and for treatment of antibody mediated…2015 American Transplant Congress
CYP3A4 Polymorphisms Correlate With Time to Achieve Tacrolimus Steady State Concentration in Lung Transplant Patients
Introduction:Tacrolimus is the main component of the immunosuppressive regimen used in patients with solid organ transplants. Tacrolimus requires blood concentration monitoring due a narrow therapeutic…2015 American Transplant Congress
Elevated Pre-Transplant Serum Troponin Is Associated With an Increased Risk of Mortality in Elderly Kidney Transplant Recipients
Introduction:Elderly patients with chronic kidney disease are nowadays more often considered for kidney transplantation although death rate is increased in this population compared to younger…2015 American Transplant Congress
HLA-C, KIR Genotypes and KIR Genotype/HLA –C Ligand Combination in Prediction of Early Acute Rejection After Liver Transplantation
Introduction; Interaction of killer immunoglobulin-like receptors (KIRs) and human leukocyte antigen class-I (HLA-I) regulates NK cytotoxicity and function. NK regulation influences on NK/T cell alloreactivity…2015 American Transplant Congress
Donor Apolipoprotein L1 Genotype Associates With Glomerular Lesions and Graft Loss in Kidney Transplants
Medical University of South Carolina, Charleston, SC.
Introduction/Aims: Previous studies have associated donor apolipoproteinL1 (APOL1) risk genotypes with risk of graft loss among kidney transplants. APOL1 risk genotypes have also been associated…2015 American Transplant Congress
Inside Out Autologous Neo-Liver Fabrication
Surgery, Stanford University School of Medicine, Stanford, CA.
Background: Creation of patient-specific replacement organs promises to address major shortcomings in transplantation. We previously described an approach to fabricate autologous, vascularized neo-organs by using…2015 American Transplant Congress
Effects of Immunosuppressives On Porcine Renal Microvascular Endothelial Cell–Activated Human T Cell Proliferation: A Cellular Model of Kidney Xenotransplantation In Vitro
Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: The creation of genetically-modified pigs has brought us closer than ever to clinical xenotransplantation. However, the optimal immunosuppressive doses still need to be established…2015 American Transplant Congress
Presence of Donor Leukocytes and Donor MHC-Cross-Dressed Recipient Cells and Its Relationship to Direct T Cell Alloresponses After Allotransplantation
We have studied the kinetics of donor cell trafficking from the graft to recipient's lymphoid organs and its correlation to the direct T cell alloresponse…
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