2015 American Transplant Congress
Costimulation Blockade Prevents Rejection of Vascularized Composite Allografts
[Background] Vascularized composite allotransplantation (VCA) is an emerging new era in transplant medicine and has become a valid therapeutic option after devastating tissue loss. The…2015 American Transplant Congress
Single Cell Phospho-Protein Analysis Demonstrates That Immunosuppressive Drugs Inhibit MAPK and mTOR Signaling Molecules in Primary Monocytes After Transplantation
Nephrology and Transplantation, Dept. of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.
Monocytes have been identified as key players driving rejection processes. It is therefore surprising that there are almost no data available about the impact of…2015 American Transplant Congress
Antibody-Induced Platelet Activation Increases Allograft Hyaluronan Fragmentation
Antibodies to MHC class I antigens have been shown to activate endothelial cells to release von Willebrand factor (vWf) and P-selectin from storage granules. These…2015 American Transplant Congress
Influence of Cold Ischemia Time in Combination With Donor Ischemic Events on Kidney Transplant Outcomes
Transplantation, Montefiore Medical Center, Bronx, NY.
Deceased-donor kidneys may be exposed to various ischemic events either from donor instability as evidenced by acute kidney injury (AKI) or donation after circulatory death…2015 American Transplant Congress
Histopathological Criteria for Elevated Risk of Delayed Graft Function in German Pretransplantation Kidney Biopsies from Deceased Donors
Introduction:Delayed graft function (DGF) is more frequent with so called marginal kidney donors. Moreover, it is linked to increased recipient mortality and inferior transplant outcome.…2015 American Transplant Congress
Clinical Outcomes of Kidney Transplan Recipients After Sirolimus Or Everolimus Conversion. Experience in a Single Center
Transplant Unit, Fundación Valle del Lili, Cali, Colombia.
Introduction. The use of m_TOR inhibitors sirolimus (SRL) and everolimus (EVL), in kidney transplant recipients (KTR) is an alternative immunosuppressive therapy to reduce or withdrawal…2015 American Transplant Congress
Assessing Pre-Vaccination Cytokine Levels to Predict Immunogenicity to Seasonal Trivalent Influenza Vaccine in Solid Organ Transplant Recipients
Multi-Organ Transplant Program, University Health Network, Toronto, Canada.
Background: The immunogenicity of seasonal trivalent influenza vaccine (TIV) in solid organ transplant (SOT) recipients remains suboptimal. We hypothesized that analysis of pre-vaccination T- and…2015 American Transplant Congress
MELD as a Predictor of Post-Transplant Survival
Department of Surgery, Johns Hopkins, Baltimore.
MELD is a reliable tool to predict liver waitlist mortality. Previous studies of MELD and post-transplant outcomes have had conflicting results.METHODS: We used generalized gamma…2015 American Transplant Congress
Sex Differences in Mortality Rate Among Patients Waiting for Liver Transplantation
1Columbia University, New York; 2Johns Hopkins University, Baltimore.
Livers are allocated according to MELD score without regard to patient demographics. However, MELD-adjusted risk of death may vary by sex, since serum creatinine level…2015 American Transplant Congress
Sarcopenia and Non-Ischemic Cardiomyopathy After Liver Transplantation
Introduction: We describe 3 cases of non-ischemic cardiomyopathy (NICM) following liver transplantation (LT) in patients with pre-transplant sarcopenia.Reports: All 3 patients were transplanted at a…
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