ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Potential Urine Protein Biomarkers for Kidney Transplantation Dysfunction Through Quantitative Proteomics

    T. Sigdel,1 N. Salomonis,2 C. Nicora,3 J. He,3 W.-J. Qian,3 D. Camp,3 M. Sarwal.1

    1UCSF, San Francisco, CA; 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3Pacific Northwest National Laboratory, Richland, WA.

    Introduction: Inability to effectively monitor transplant injuries leads to immune and non-immune mediated graft dysfunction. A non-invasive tool to monitor such injuries is an unmet…
  • 2015 American Transplant Congress

    ABCB1 Haplotypes, Sex, Calcineurin Inhibitors and Lipid Profiles Post-Renal Transplant

    C. Meaney,1,2 R. Venuto,3 D. Brazeau,4 J. Consiglio,5 L. Cooper,1 G. Wilding,5 K. Tornatore.1,2,3

    1NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY; 2School of Pharmacy, Buffalo, NY; 3Medicine, School of Medicine, Buffalo, NY; 4University of New England College of Pharmacy, Portland, ME; 5Biostatistics, School of Public Health, University at Buffalo, Buffalo, NY.

    Purpose: Hyperlipidemia is common in renal transplant recipients (RTR) during calcineurin inhibitor (CNI) immunosuppression. P-glycoprotein (P-gp) is an efflux transporter encoded by ABCB1 that modulates…
  • 2015 American Transplant Congress

    Somatostatin (Eumedica®) Infusion Allows Modulating Graft Flows and Gradients in Liver Transplantation. Results of a Randomized, Double Blind, Placebo Controlled Trial

    R. Troisi,1 A. Croo,1 E. Codarin,3 E. De Wolf,1 J. Van Limmen,4 G. Antoniali,3 B. Heyse,4 L. De Baerdemaeker,4 I. Colle,5 G. Tell,3 M. Sainz-Barriga.1,2

    1General Hepatobiliary Surgery Liver Transplantation Service, Ghent University Hospital Medical School, Ghent, Belgium; 2Digestive Surgery & Liver Transplantation, University of Tours, Tours, France; 3Medical & Biological Sciences, University of Udine, Udine, Italy; 4Anesthesiology, Ghent University Hospital Medical School, Ghent, Belgium; 5Gastroenterology, Ghent University Hospital Medical School, Ghent, Belgium.

    Background: Somatostatin (SST) infusion decrease portal pressure in acute variceal bleeding in cirrhotic patients. Despite liver transplantation (LTx), recipients with portal hypertension (PHT) display different…
  • 2015 American Transplant Congress

    Immune Phenotyping of Peripheral Blood Samples from the CTOT-10 Belatacept Study

    Y. Suessmuth,1 L. Stempora,1 B. Johnson,1 J. Cheeseman,1 Y. Morrison,4 N. Bridges,4 D. Ikle,5 S. Tomlanovich,3 P. Stock,3 R. Mannon,2 K. Newell,1 C. Larsen,1 A. Mehta.1

    1Emory Transplant Center, Atlanta; 2University of Alabama, Birmingham; 3University of California San Francisco, San Francisco; 4NIAID/ NIH, Bethesda; 5Rho, Chapel Hill, NC.

    The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…
  • 2015 American Transplant Congress

    Transplant Glomerulopathy in a Novel Model of Chronic Antibody Mediated Rejection Is Associated With DSA and Glomerular IgM

    S. Panzer,1 S. Reese,1 N. Wilson Schlei,1 W. Zhong,2 A. Djamali.1

    1Medicine, University of Wisconsin Madison, Madison, WI; 2Pathology, University of Wisconsin Madison, Madison, WI.

    PurposeChronic active antibody mediated rejection (cAMR) and transplant glomerulopathy (TG) are major determinants of long-term allograft survival. However, the contribution of DSA and glomerular immunoglobulins…
  • 2015 American Transplant Congress

    Native Americans and Post-Kidney Transplant Follow-Up: Lower in Quantity and Quality?

    S. Stith,1 F. Barrantes.2

    1Department of Economics, University of New Mexico, Albuquerque, NM; 2Renal Medicine Associates/Presbyterian Transplant Center, Albuquerque, NM.

    Background: Native Americans have been shown to face decreased access to waitlisting and transplantation.They appear to have similar short-term survival prospects post-transplant to those of…
  • 2015 American Transplant Congress

    Emerging Strategies to Screen Kidney Offers Based on the Kidney Donor Profile Index (KDPI)

    D. Stewart,1 A. Kucheryavaya,1 G. Boyle,1 R. Metzger,2,3 M. Aeder,4 R. Formica.5

    1UNOS, Richmond, VA; 2Florida Hosp, Orlando, FL; 3Translife, Orlando, FL; 4Univ Hosp Case Med Ctr, Cleveland, OH; 5Yale Univ, New Haven, CT.

    Background: In the Organ Procurement and Transplantation Network's (OPTN) new kidney allocation system, kidney offers are screened by setting for each candidate a maximum acceptable…
  • 2015 American Transplant Congress

    Identifying Predictors for 30-Day Readmission in Renal Transplant Recipients

    J. Weber,1 B. Astor,2 D. Cray,3 A. Djamali,2 D. Kaufman,4 D. Mandelbrot,2 S. Parajuli,2 M. Schanning,3 E. Snyder,1 M. Mohamed.2

    1Surgical Nursing, UW Hospital & Clinics, Madison, WI; 2Department of Medicine, UW School of Medicine & Public Health, Madison, WI; 3Business Planning & Analysis Department, UW Hospital & Clinics, Madison, WI; 4Department of Surgery, UW School of Medicine & Public Health, Madison, WI.

    Purpose: The aim of this study is to determine risk factors associated with 30-day hospital readmissions in renal transplant recipients.Methods: This single center longitudinal study…
  • 2015 American Transplant Congress

    Medication Non-Adherence in Those Waiting for a Transplant

    M. Wakefield,1 D. Murillo,2 C. Russell,3 C. Ashbaugh,1 S. Potts,2 L. Blakley,2 A. Deere.1

    1Department of Surgery, University of Missouri, Columbia, MO; 2Transplant Institute, Research Hospital, Kansas City, MO; 3School of Nursing and Health Studies, University of Missouri-Kansas City, Kansas City, MO.

    Purpose: Though poor medication adherence among adult kidney transplant patients is alarmingly high with distressing consequences, no one has systematically examined medication non-adherence in those…
  • 2015 American Transplant Congress

    Mesenchymal Stem Cells (MSCs) Transfusion for Desensitization of Positive Lymphocyte Cross Match (LCM) or Panel Reactive Antibodies (PRA) Before Kidney Transplantation – Outcome of 16 Cases

    G. Saadi,1 K. Eweda,2 M. Hassaballa,1 F. Fadel,3 E. Aziz,2 M. Roshdi,1 M. El Ansary,4 I. Aziz,4 W. Ismail,5 A. Atef,1 S. Hamid.4

    1Internal Medicine and Nephrology, Cairo University, Cairo, Egypt; 2Nephrology, Army Hospital, Cairo, Egypt; 3Pediatric Nephrology, Cairo University, Cairo, Egypt; 4Clinical Pathology, Cairo University, Cairo, Egypt; 5Pathology, Beni Sweif University, Beni Sweif City, Egypt.

    Immunomodulatory function of MSCs may correct positive PRA or LCM in highly-sensitized patients. We evaluate donor specific or 3rd party MSCs transfusion in 16 patients…
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