2015 American Transplant Congress
Differential Expression and Function of ASC and Nlrp3 Inflammasome Adaptors in Hematopoietic Stem Cells (HSCs)
Medicine, University of California San Diego, San Diego, CA.
HSCs are activated by pattern recognition receptors (PRRs), which might provide novel targets for improved engraftment. How PRRs affect HSC engraftment after BM transplantation is…2015 American Transplant Congress
Current Status of US Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Intestine Transplant Registry
The purpose of this study is to analyze the current status of US intestinal transplantation (IT). As of 9/19/2014, 2441 IT have been performed in…2015 American Transplant Congress
Outcome of Renal Sparing Protocol in a Cross-Sectional Analysis After Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Calcineurin inhibitors (CNIs) are the mainstay of immunotherapy after heart transplantation. Unfortunately CNIs are associated with renal dysfunction due to nephrotoxic side effects. The…2015 American Transplant Congress
Comparison of Risk Factors and Outcomes of Daptomycin-Susceptible and -Nonsusceptible Enterococcus Infections in Liver Transplant Recipients
University of Virginia, Charlottesville, VA.
PurposeDaptomycin (DAP) has become an important therapeutic agent to treat infections due to vancomycin-resistant Enterococcus faecium (VRE), including in liver transplant recipients (LTRs); however, DAP-nonsusceptible…2015 American Transplant Congress
Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism in Nonhuman Primates
Transplant Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Background: We have previously reported a successful induction of mixed chimerism and the long-term acceptance of renal allografts in MHC-mismatched nonhuman primates. In this study,…2015 American Transplant Congress
Human Hematopoietic Chimeric Cells as a Novel Approach for Tolerance Induction After Transplantation
Background: Cellular therapies represent a new promising approach for transplant tolerance induction. One of the methods for immune response modulation in solid organ and vascularized…2015 American Transplant Congress
Efficacy, Safety and Pharmacokinetics of Once-Daily, MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus (Prograf®) in De Novo Kidney Transplant Recipient Sub-Groups: A 2 Year Phase 3 Randomized, Double-Blind, Double-Dummy, Trial
Differences in tacrolimus (tac) metabolism are evident in certain populations; in particular, lower tac bioavailability has been shown in females and black kidney transplant recipients…2015 American Transplant Congress
Do Pre-Procurement Factors Affect Vascular Resistance During Pulsitile Perfusion of Deceased Donor Kidneys?
Background: Pulsatile perfusion (PP) of explanted deceased donor kidneys can improve early function after transplantation, as compared to static cold flushing and storage. High vascular…2015 American Transplant Congress
MDRD4 Equation Is Better Than CKD-EPI, Cockroft-Gault and Nankivell Equations to Estimate Glomerular Filtration Rate in Renal Transplantation
To evaluate which estimated GFR (eGFR) equation is the most appropriate to in kidney transplanted (KTx) recipients, we obtained data from all plasma EDTA-Cr51 clearances…2015 American Transplant Congress
Absence of Low-Grade Proteinuria Is Associated With Improved Outcomes in Patients With Worse 3 Month Graft Function in Renal Transplantation
1Leeds Teaching Hospitals, Leeds, United Kingdom; 2University of Pittsburgh, Pittsburgh.
Low-grade proteinuria has been shown to be associated with adverse outcomes after renal transplantation. However most patients with proteinuria have worse eGFR and this interaction…
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