Am J Transplant, Volume 5, Suppl 3 Archives - Page 22 of 170 - ATC Abstracts

2015 American Transplant Congress
Implementation of Evidence-Based Guidelines for Cytomegalovirus Prevention in Pediatric Solid Organ Transplantation
L. Danziger-Isakov, T. Hemmelgarn, R. Kohli, D. Lazear, M. Lake, J. Goebel, C. Castleberry, J. Courter, S. Kacoshis, M. Schecter, D. Witte, E. Clark, J. Bucuvalas.
Cincinnati Children's, Cincinnati.
Optimal strategies to prevent cytomegalovirus (CMV) disease after pediatric solid organ transplantation (SOT) in a cost effective manner are uncertain. We evaluated the frequency of…
2015 American Transplant Congress
Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1
D. Chen, J. Chen, W. Peng.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Key Laboratory of Nephropathy, Zhejiang Province; Kidney Disease Immunology Laboratory, The Third Grade Laboratory, State Administration of Traditional Chinese.
ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…
2015 American Transplant Congress
Invasive CMV-Infection of the Duodenal Cuff – An Underestimated Entity of CMV Infection and Its Potential Impact On Outcome After Pancreas Transplantation
A. Biglarnia,¹ B. von Zur-Mühlen,¹ S. Yamamoto,¹ D. Berglund,¹ M. Wagner,² A. Sedigh,¹ G. Tufveson,¹ E. Larsson,³ F. Sund.²
¹Transplantation, Surgical Sciences, Uppsala, Sweden; ²Medical Scinces, Upsala, Sweden; ³Genetics and Pathology, Uppsala, Sweden.
IntroductionWe present data on the incidence of focal invasive CMV-infection of the duodenal cuff and its potential impact on clinical outcome after pancreas transplantation (PT).Material…
2015 American Transplant Congress
Furthering the Link Between Ischemia and Immunity: Development of New Antibody Following Prolonged Delayed Graft Function
A. Gilbert,¹ E. Hall,¹ O. Timofeeva,² M. Awwad,² M. Grafals,¹ P. Weems,¹ D. Li,² S. Rosen-Bronson,² J. Moore,¹ B. Javaid,¹ M. Cooper.¹
¹Department of Surgery, MedStar Georgetown Transplant Institute, Washington, DC; ²Department of Pathology, MedStar Georgetown Transplant Institute, Washington, DC.
Introduction The purpose of this study is to examine the relationship between prolonged ischemia (delayed graft function - DGF) and the development of de novo…
2015 American Transplant Congress
Discard of Kidneys at the Margin: ECD Versus KDPI Era
S. Bae, A. Massie, D. Segev.
Johns Hopkins, Baltimore, MD.
BACKGROUND: Since 3/26/2012, the Kidney Donor Profile Index (KDPI), a percentile score reflecting donor-associated risk, has been provided with all deceased-donor kidney offers. We investigated…
2015 American Transplant Congress
New SRTR Risk-Adjustment Models for Adult Kidney Transplant Outcomes
J. Snyder,¹ N. Salkowski,¹ D. Zaun,¹ H. Xiong,¹ S. Leppke,¹ B. Thompson,¹ D. Segev,^1,2 L. Hunsicker,¹ A. Israni,¹ B. Kasiske.¹
¹Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; ²Johns Hopkins University, Baltimore, MD.
Following a recommendation of the Consensus Conference on Transplant Program Quality and Surveillance, SRTR implemented a 3-year rolling cycle to rebuild the statistical models used…
2015 American Transplant Congress
Toll-Like Receptor 4-Signaling Abrogates Inhibitory Effect of Calcineurin Inhibitor on B-Cells Responding to Blood Group A-Antigens
H. Sakai, Y. Tanaka, H. Ohdan.
Transplant Unit, Hiroshima University, Hiroshima, Japan.
Aim: Bacterial infection following ABO-incompatible organ-transplantation is associated with refractory Ab-mediated rejection. Here, we investigated the influence of toll-like receptor (TLR)-signaling, via the binding of…
2015 American Transplant Congress
Long Term Outcomes of Tocilizumab Therapy for DSA+ Antibody Mediated Rejection (ABMR) Resistant to IVIG + Rituxan (I+R) Treatment
J. Choi,¹ A. Vo,¹ J. Kahwaji,¹ M. Haas,² N. Reinsmoen,³ D. Puliyanda,¹ A. Peng,¹ R. Villicana,¹ S. Jordan.¹
¹CTC, Cedars Sinai, Los Angeles, CA; ²Pathology, Cedars-Sinai, Los Angeles, CA; ³HLA Laboratory, Cedars-Sinai, Los Angeles, CA.
Intro: Limited options are available for treatment of ABMR in highly-HLA sensitized patients (HS). Treatment options include I+R, PLEX+I+/- R, C5-inhibitor & bortezomib. Approximately 25%…
2015 American Transplant Congress
Rejection Triggers Liver Transplant Tolerance: Involvement of Mesenchyma-Meidated Immune Control Mechanisms
M. Morita, D. Joyce, C. Miller, J. Fung, L. Lu, S. Qian.
Immunology, Lerner Research Institute; 2General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.
Successful organ transplantation relies on lifelong immunosuppression, associated with severe side effects. Induction of tolerance is ideal but elusive in clinic. Indeed spontaneous liver transplant…
2015 American Transplant Congress
Sensitization Level at Retransplant Among Non-Sensitized Pediatric Recipients of First Deceased Donor Kidney Transplants Not Affected by DR Mismatch Level
W. Cherikh,¹ A. Wilk,¹ H. McGehee,¹ E. Brewer.²
¹United Network for Organ Sharing, Richmond, VA; ²Baylor Coll Med & Texas Children's Hosp, Houston, TX.
Background. Most pediatric (ped) kidney (KI) recipients (recips) received 1- or 2-DR HLA mistmached (MM) deceased donor (DD) kidneys. The degree of HLA MM between…