2015 American Transplant Congress
Molecular Marker Strategies Supporting the Novartis US92 Study- A Discovery Study of Protein Biomarkers for Kidney Function (eGFR) and Acute Rejection in Serum from Renal Transplant Patients
Purpose. Protein biomarkers have the potential to allow for earlier and more specific diagnosis of kidney injury in kidney transplant patients than established clinical markers…2015 American Transplant Congress
Associations Between Deceased-Donor Urine Biomarkers of Kidney Injury and 6-Month Kidney Transplant Function
TRIBE-AKI Consortium, New Haven, CT.
Assessment of organ quality is integral to allocation, yet existing tools have a limited ability to predict important transplant outcomes. We evaluated whether injury biomarkers,…2015 American Transplant Congress
Socioeconomic Predictors of Organ Donation in Pediatric Donors
Transplant Surgery, University of Kentucky, Lexington, KY.
BACKGROUND: The availability of pediatric donors does not meet the demand for pediatric recipients who are listed and waiting transplantation. There is a need to…2015 American Transplant Congress
Overexpression of 2B4 Inhibits the Expansion and Function of Donor-Reactive CD8+ T Cells in Selective Lymphoid Compartments
Department of Surgery, Emory University, Atlanta, GA.
2B4 is an immunoglobulin superfamily member expressed constitutively on NK cells, and inducibly on some CD8+ T cells. We recently showed in a murine skin…2015 American Transplant Congress
Absence of Nucleotide-Binding Oligomerization Domain-Containing Protein 1 and 2 Modifies Adaptive Immune Responses
Background:The NOD family of intracellular pattern recognition receptors (PRRs) plays a key role in immune responses to microbial and danger signals. This family of proteins…2015 American Transplant Congress
Risk Factors Influencing Mammography Screening During Kidney Transplant Evaluation
Transplant Institute, University Hospitals & Case Western Reserve University, Cleveland, OH.
INTRO:Transplant centers typically require mammography (MMG) for women ≥ 40 as part of the evaluation process. The American Cancer Society recommends annual mammograms for the…2015 American Transplant Congress
Attenuating Racial Disparities in Kidney Transplantation Through the Use of Potent Immunosuppression Regimens
Medical University of South Carolina, Charleston, SC.
African-American (AA) kidney transplant (KTX) recipients have higher rates of graft loss, which may be partially attributed to higher immunologic risk. The aim of this…2015 American Transplant Congress
The Liver X Receptor Alpha (LXRα) Knockout Protect Liver Against Ischemia-Reperfusin Injury in Mice
Background: Liver X Receptor Alpha (LXRα) is a transcription factor crucial for cholesterol, fatty acid, and glucose homeostasis. We hypothesize that LXRαKO may promote hepatocellular…2015 American Transplant Congress
Recipient Myelomonocytic Cells With Activated Hypoxia-Inducible Factor Alleviate Ischemia-Reperfusion Injury in Mouse Heart Allografts
Aim: To investigate the effect of HIF-1α and -2α activation in myelomonocytic cells during the early phase after ischemia-reperfusion (IRI) injury of mouse allogenic heart…2015 American Transplant Congress
The Impact of Cytokine Release Caused By Induction Immunosupression On Nitric Oxide in Renal transplantation
IntroductionVarying induction immunosuppression regimens have a differential impact on the pattern of cytokine release. Pro-inflammatory cytokines stimulate endothelial cells causing secretion of NO. Serum nitrite…
American Transplant Congress abstracts