2015 American Transplant Congress
Decreased Expression of Mitochondrial Aldehyde Dehydrogenase 2 Induces Liver Injury Via Activation of the MAPK Pathway in Grafts from Brain-Dead Donors
Objective: To determine the role of ALDH2 in the injury of liver from brain-dead donors.Methods: Using brain-dead rabbit model, the expression of ALDH2 and apoptosis…2015 American Transplant Congress
Transient Lymphopenia Breaks Costimulatory Blockade-Based Transplant Tolerance and Initiates Allograft Rejection
【Background and Objective】: Lymphopenia is induced by lymphoablative therapies and chronic viral infections. Lymphopenia is observed in some pathological and physiological processes, including chronic viral…2015 American Transplant Congress
Aldosterone Acts Directly On T Cells, and Promotes Production of Inflammatory Cytokines
Department of Developmental, Molecular and Chemical Biolgy, Tufts University Medical School, Boston.
Aldosterone is a mineralocorticoid hormone involved in the regulation of blood electrolyte concentration, blood pressure and blood volume. The primary receptor for aldosterone is the…2015 American Transplant Congress
Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients
Objective: Recent studies found osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to…2015 American Transplant Congress
Cultural Domains Affecting Organ Donation in Indian Country
Background: The prevalence of end-stage renal disease is 3.5 times greater among the >2.5 million Native Americans or Alaskan Natives (NAs) in the US than…2015 American Transplant Congress
Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function
Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…2015 American Transplant Congress
The Impact of FcγRIIA, FcγRIIIA and C1QA Genes Polymorphism On Infectious Complications Following Renal Transplantation
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
AIM- Infectious complication is the leading cause of graft and patient loss after renal transplantation (RT). Under immunosuppressive condition when acquired immunity is suppressed, components…2015 American Transplant Congress
Perfusion Disturbances and Local Infarctions After Experimental Kidney Transplantation Corralte With the Duration of Cold Ischemia Time
Background: Kidney transplantation in mice is challenging but offers good translational models to study mechanisms of disease. In this study allogenic and isogenic kidney transplantation…2015 American Transplant Congress
Steroid-Free Quadruple Induction Regimen With Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Reduces Incidence of Biopsy-Proven Acute Rejection and Toxicity Profile Compared to the Standard Triple Regimen
Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant clinical problem even with low exposure regimens. On the other hand, CNI-free…2015 American Transplant Congress
Prospective Study of a Steroid Free, Low Dose Tacrolimus and Everolimus Combination Regimen in Kidney Transplant
Calcineurin(CNI) based therapy is the cornerstone of immunosuppresion(IS) after kidney transplant. However chronic nephrotoxicity from CNI as been implicated in post-transplant renal dysfunction. We hypothesized…
American Transplant Congress abstracts