ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Impact of Ischemia/Reperfusion Injury On Liver Allografts from Deceased After Cardiac Death Versus Deceased After Brain Death Donors

    B. Sayed, J. Xu, A. Casas-Ferreira, P. Srinivasan, N. Heaton, Y. Ma, C. Legido-Quigley, S. Fuggle, W. Jassem.

    1Liver Transplant Unit, Institute of Liver Studies, King's College Hospital, London, United Kingdom; Department of Transplant Surgery, Emory University, Atlanta, United Kingdom; Institute of Pharmaceutical Science, King's College Hospital, London, United Kingdom; Department of Analytical Chemistry, University of Salamanca, Salamanca, Spain; Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.

    Background and Aims:The shortage of appropriate organs for transplantation has led to the use of organs from donors after cardiac death. The pathophysiologic processes associated…
  • 2015 American Transplant Congress

    Outcomes Following Endovascular Treatment of Hepatic Artery Stenosis Following Liver Transplantation

    J. Seal,1 H. Bohorquez,1 L. Le,2 W. Terral,2 A. Cohen,1 I. Carmody,1 D. Bruce,1 T. Reichman,1 E. Ahmed,1 W. Sternbergh,2 G. Loss.1

    1Multi-Organ Transplant Institute, Ochsner Health System, New Orleans, LA; 2Department of Surgery, Ochsner Health Systems, New Orleans, LA.

    Endovascular treatment of hepatic artery stenosis (HAS) after liver transplantation offers a less invasive alternative to surgical revision or retransplantation. However, outcomes following endovascular treatment…
  • 2015 American Transplant Congress

    Birth Weight as a Marker of Nephron Mass: Impact on Renal Allograft Function

    T. Schachtner,1,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charité Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany.

    Nephron number has been considered a major determinant of renal allograft function and outcome. It has been demonstrated that low birth weights give rise to…
  • 2015 American Transplant Congress

    Learning from Failures: A 7-Year Analysis of a Multi-Institutional Kidney Paired Donation Registry

    D. Fumo,1,2 V. Kapoor,1 L. Reece,2 S. Rees,2 J. Kopke,2 S. Stepkowski,1 C. Smith,1,2 M. Rees.1,2

    1University of Toledo Medical Center, Toledo, OH; 2Alliance for Paired Donation, Maumee, OH.

    Failure to convert computer-identified possible Kidney Paired Donation (KPD) exchanges into transplants has prevented KPD from reaching its full potential. The purpose of this study…
  • 2015 American Transplant Congress

    The Impact of Preoperative Antimicrobial Prophylaxis on Device-Related Infections in Recipients of Long-Term Mechanical Circulatory Support (MCS)

    I. El Lakkis,1 K. Lietz,2 C. Derber,1 U. Kelly,1 C. Wilson,1 A. Hoedt,2 P. Bourasssa,2 B. Smith,2 M. McGrath,2 J. Herre,2 M. Mooney.1

    1Eastern Virginia Medical School, Norfolk, VA; 2Sentara Norfolk General Hospital, Norfolk, VA.

    Purpose: Although preoperative antimicrobial prophylaxis is recommended for patients undergoing long-term MCS device implantation, there is a lack of consensus as to the optimal preoperative…
  • 2015 American Transplant Congress

    Inadequate Overall Immunosuppression Is a Risk for Late Acute Rejection Despite Alemtuzumab Induction in Simultaneous Pancreas Kidney Transplant Recipients

    J. Bank,1 M. Mallat,1 P. van der Boog,1 D. Braat,2 J. Ringers,2 M. Vergunst,3 S. Heidt,3 F. Claas,3 M. Reinders,1 J. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Surgery, LUMC, Leiden, Netherlands; 3IHB, LUMC, Leiden, Netherlands.

    Introduction: Simultaneous pancreas-kidney transplantation (SPK) has become the treatment of choice for patients with end-stage renal disease due to Type 1 Diabetes Mellitus. SPK is…
  • 2015 American Transplant Congress

    Dual Induction Therapy With Anti-Thymocyte Globulin and Basiliximab in Simultaneous Pancreas-Kidney Transplantation Reduced Incidence of Acute Rejection

    K. Miki, K. Iwadoh, I. Nakajima, S. Fuchinoue.

    Tokyo Women Medical University, Kidney Center, Tokyo, Kawadacho, Japan.

    【Background】Induction therapy in simultaneous pancreas-kidney transplant (SPK) recipients has been a common practice because a consequence of acute rejection (AR) in SPK could result in…
  • 2015 American Transplant Congress

    Kidney Retransplantation in the Ipsilateral Iliac Fossa; a Surgical Challenge

    L. Ooms,1 J. Roodnat,2 F. Dor,1 K. Tran,1 D. Kimenai,1 J. IJzermans,1 T. Terkivatan.1

    1Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands; 2Nephrology, Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction: The aim of this study is to review the surgical outcome of kidney retransplantation in the ipsilateral iliac fossa in comparison to first kidney…
  • 2015 American Transplant Congress

    Distinct Clinical Relevance of BAFF Expression Within the Kidney Graft and Soluble BAFF Serum Levels Indicate Confined Alloimmune Responses Disconnected from the Periphery

    E. Campos,1,2 K. Mine,1 A. Goncalves-Primo,1,2 M. Soares,4 M. Franco,2 J. Medina-Pestana,2,3 H. Tedesco-Silva,3 M. Gerbase-DeLima.1,2

    1Instituto de Imunogenética, AFIP, São Paulo, SP, Brazil; 2Universidade Federal de São Paulo, São Paulo, SP, Brazil; 3Hospital do Rim e Hipertensão- FOR, São Paulo, SP, Brazil; 4Universidade Federal do Parana, Curitiba, PR, Brazil.

    As soluble B-cell activating factor (BAFF) serum levels (sBAFF) may not reflect BAFF concentrations within the graft, what could be related to the inconsistencies in…
  • 2015 American Transplant Congress

    Differentially Expressed IL-6Rα and GP130 Genes in Kidney Biopsies (Bxs) Suggests Different Roles of IL-6 Signaling in Antibody (ABMR)- and Cell (CMR)-Mediated Rejection

    H. Zhang,1 D. Thomas,1 J. Kowalewska,2 E. Suviolahti,1 H. Shafi,2 C. Nast,2 A. Gertych,2 A. Vo,1 M. Haas,2 S. Jordan,1 M. Toyoda.1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; 2Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: IL-6 exerts immunoregulatory properties through IL-6 receptors, IL-6Rα and gp130. Our previous studies suggested the involvement of antibody-dependent cellular cytotoxicity (ADCC) and its related…
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