2015 American Transplant Congress
Change in Frailty Status Over Time Among In-Center Hemodialysis ESRD Patients in the ACTIVE/ ADIPOSE Study
Emory University, Atlanta, GA.
Introduction: Frailty among End Stage Renal Disease (ESRD) is associated with poor health outcomes, including delayed graft function and hospitalization following transplantation. Although frailty is…2015 American Transplant Congress
Highly Accurate High-Resolution HLA Imputation Using Dense Genotyping Data
HLA similarity between donors (D) and recipients (R) of solid organ transplantation (SOT) plays a central role in determining the risk of rejection or graft-versus-host…2015 American Transplant Congress
Differentially Expressed Genes in Immunosuppressed Kidney Transplant Recipients
Introduction: In our effort to personalize immunosuppressive therapies we performed RNA sequencing (RNAseq) to identify differentially expressed genes (DEGs) after kidney transplant (tx) and the…2015 American Transplant Congress
Mesenchymal Stem Cell Therapy to Improve Functional Outcome in Vascular Composite Allotransplantation (VCA)
Madigan Army Medical Center, Tacoma.
Introduction: Although over 200 VCA including hand and face transplants have been performed worldwide with encouraging graft survival outcomes, long-term success with motor and sensory…2015 American Transplant Congress
Cardiac Xenotransplantation: Reconstituted B Cells After Rituxan Treatment Maintain Their Repertoire But Have a Muted Response to Xenoantigens
1CSRP/NIH/NHLBI, NIH, Bethesda, MD; 2DVR/ORS, NIH, Bethesda, MD; 3Revivicor Inc, Blacksburg, VA.
Background: Xentoranplantation (XTx) remains an option for end stage organ failure. Recently we have reported cardiac xenograft survival of over one year pig to baboon…2015 American Transplant Congress
Host NK Cell Allorecognition of Passenger Donor Lymphocytes Within Allografts Is Essential for Preventing Augmentation of Recipient Adaptive Alloimmunity
Department of Surgery, University of Cambridge, Cambridge, United Kingdom.
Background:Memory T cells are now appreciated to reside in peripheral non-lymphoid tissue, but how their presence within solid organ allografts impacts upon transplant outcomes is…2015 American Transplant Congress
Antibody-Mediated Rejection Is Associated With Higher Serum Levels of CXCL13 and CCL21 in Renal Transplant Patients and Altered By Bortezomib/Rituximab Treatment
In renal transplant patients (pts), B- and plasma cells (PC) are crucial for donor-specific HLA antibody (DSA) formation. The underlying mechanisms, which lead to B…2015 American Transplant Congress
Racial Disparities in Preemptive Kidney Transplant Referrals in Georgia: Data from the RaDIANT Community Study
PurposeAccess to kidney transplantation (KTx) before initiation of dialysis is associated with improved patient and graft survival, enhanced quality of life, and decreased hospital readmissions…2015 American Transplant Congress
National Outcomes of Kidney Transplantation from Diabetic Donors
Despite limited outcomes data, kidneys from diabetic donors are being increasingly used in the USA. To compare outcomes in recipients of kidneys from diabetic versus…2015 American Transplant Congress
Impact of Type of Tacrolimus Assay on Therapeutic Drug Monitoring: Need for Standardization
Internal Medicine/Nephrology, Washington University School of Medicine, St. Louis, MO.
Background: Multiple assays are available for measuring tacrolimus (FK) levels and these are not currently standardized. A designated laboratory transitioned their FK assay from Enzyme…
American Transplant Congress abstracts