2015 American Transplant Congress
Molecular Classifiers Accurately Measure the Degree of Fibrosis in Human Kidney Transplant Biopsies
University of Alberta, Edmonton, Canada.
Irreversible injury in organ transplants is an important clinical parameter, and is estimated by histology as the observed ci lesion, but with considerable inter-observer variability…2015 American Transplant Congress
Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction
Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…2015 American Transplant Congress
Fast Track of Adult-to-Adult Live Donor Liver Transplant Recipients: Avoiding ICU Admission Reduces Complications and Post Transplant Hospital Stay
Toronto General Hospital, Toronto, ON, Canada.
Objective: We investigated if fast track of adult-to-adult live donor liver transplant (LDLT) recipients is safe and provides benefits for the post transplant hospital stay.Methods:…2015 American Transplant Congress
Outcomes After Right Kidney Living Donor Transplant Are Associated With Center Volume
Surgery/Transplantation, University of Alabama at Birmingham, Birmingham, AL.
Background: Right kidney living donor transplant (RKLDT) is a high-risk, low-volume procedure that is associated with increased risk for early graft failure. It is unclear…2015 American Transplant Congress
Are Living Kidney Donors Who Apply Via a Web-Based Screening Application as Likely to Be Evaluated and Donate as Compared to Phone Applicants?
Vanderbilt University, Nashville.
Purpose: Most transplant centers screen self-referring donors using phone and written surveys. Previous research at our center has shown that a web-based application for screening…2015 American Transplant Congress
High Atherosclerotic Burden in Pediatric Lung Transplant Recipients
Purpose: Pediatric lung transplant patients have been reported to have an increased incidence of hypertension. This incidence might be caused by the treatment with calcineurin…2015 American Transplant Congress
Kidney Transplantation in the Septuagenarian
Department of Transplantation, Mayo Clinic, Jacksonville, FL.
The elderly ESRD population in the US continues to grow. National data demonstrates that both patient (PS) and graft survival (GS) at 1 and 5…2015 American Transplant Congress
Clinical Significance of Estimated DSA MFI Values at 1,000 C1q MFI for Differentiation Between Harmful and Harmless DSA
INTRODUCTIONControl of chronic antibody mediated rejection (CAMR) is essential for further improvement of long-term graft survival. Early detection of de novo donor specific antibodies (DSA)…2015 American Transplant Congress
Validation of a Blood and Biopsy Gene Expression-Based Molecular Diagnostics for Subclinical Acute Rejection: Comparing DNA Microarrays Vs. Next-Generation RNA Sequencing
1The Scripps Research Institute, La Jolla, CA; 2Northwestern University, Chicago, IL.
Background: Microarray-based gene expression signatures for clinical diagnostics are well described. However, microarrays lack advantages offered by newer technologies such as Next Generation Sequencing (NGS):…2015 American Transplant Congress
Urinary Cell-Free DNA Is a Sensitive Marker of Early Renal Transplant Injury
Surgery, UC San Francisco, San Francisco, CA.
Introduction:Circulating donor-derived cell-free DNA (dd-cfDNA) has been reported as a surrogate of transplant injury in the blood but requires expensive donor and recipient DNA sequencing.Method:…
