2015 American Transplant Congress
In Vivo Expansion of Donor-Specific Regulatory T Cells by a New Triazolopyrimidine Derivative and Donor-Specific Transfusion
Background: We have previously demonstrated that a new triazolopyrimidine derivative, NK026680 (NK) prevents activation/maturation of dendritic cells. This study investigated whether NK together with donor-specific…2015 American Transplant Congress
CHBP Suppresses Acute Rejection by Inhibition Maturation of Dendritic Cells though Jak-2/STAT3/SOCS1 Signal in Rat Kidney Transplantation
Background. Renal acute rejection (AR) affects both allografts and recipients survival. We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP), which exerts promising…2015 American Transplant Congress
Molecular Correlates of Endothelial mTOR Activation in Heart Transplants Recipients
Paris Transplant Group & ATAGC, Paris - Edmonton, France.
BackgroundThe detection of phosphorylated effectors of the mTOR pathway in endothelial cells has been associated with in allograft rejection in animal models. The aim of…2015 American Transplant Congress
Intra-Renal Cytokine Measurement Detected During Kidney Allograft Biopsies Portend Severity of Histological Injury
Division of Nephrology, University of Washington, Seattle, WA.
Histological changes observed on renal allograft biopsies, although considered the current standard for evaluation of allograft injury, lack specificity and disease activity assessment. We devised…2015 American Transplant Congress
Predicting and Preventing 30-Day Readmission Following Kidney Transplantation: A Single Center Study
Purpose: Readmissions are a major morbidity following kidney transplantation (KT). Prior studies report a 30-day readmission rate of 30%. Limited data exist on risk facotors…2015 American Transplant Congress
Ureteral Length in Living Donor Kidney Transplantation; Does Size Matter?
Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands.
Introduction: Urological complications are common after kidney transplantation. The aim of this study is to evaluate the effect of ureteral length on ureter strictures or…2015 American Transplant Congress
Pancreas After Failed Islet Transplantation; a Successful Strategy to Maintain Insulin Independence
Introduction: As islet transplantation (tx) remains an experimental and uninsured procedure, there are no established protocols to achieve insulin independence following failure of the islet…2015 American Transplant Congress
Noncanonical Anergic Alloreactive B Cells in Transplantation Tolerance
Depart of Surgery, University of Chicago, Chicago.
The observation that operationally tolerant patients (TOL) display higher numbers of blood B cells and a B cell gene signature compared to stable kidney allograft…2015 American Transplant Congress
Socioeconomic Determinants of Racial Disparities in Access to Preemptive Live Donor Kidney Transplantation
Racial/ethnic minorities have less access to preemptive live donor kidney transplantation (PLDKT) than whites. Our objective was to examine determinants of racial/ethnic disparities in PLDKTs…2015 American Transplant Congress
Inhibition of Endogenous Memory CD8 T Cell Infiltration Into Cardiac Allografts Subjected to Prolonged Cold Ischemic Storage Is Required to Promote Long-Term Graft Survival
Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts and produce IFN-γ in response to donor class І MHC within 24 hrs after graft reperfusion…
American Transplant Congress abstracts