ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Recipient Immunity to Murine Cytomegalovirus Influences Natural Killer Cell Responses in Infected Renal Allografts

    M. Shimamura,1 M. Li,1 B. Chen,2 J. George.2

    1Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL; 2Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham.

    BACKGROUND: Human cytomegalovirus (CMV) is associated epidemiologically with renal allograft loss, but the impact of recipient CMV immunity upon graft survival is unclear. Natural killer…
  • 2015 American Transplant Congress

    The Role of Quantitative Assay of Urinary Decoy Cells as a Screening and Follow-Up Tool in Renal Transplant Recipients With Polyomavirus BK Infection

    G. Huang, J. Qiu, C.-X. Wang, J.-G. Fei, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.

    Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Polyomavirus BK nephropathy (BKVN) is an important infectious complication in kidney transplant patients. Urinary cytology is effective for early diagnosis of BKVN. However, quantitative assay…
  • 2015 American Transplant Congress

    Molecular Features of Isolated Arteriolar Hyalinosis in Renal Transplant Biopsies

    L. Kamal, P. O Broin, Y. Bao, A. Golden, E. Akalin.

    Einstein/Montefiore Transplant Program, Computational Genomics Facility, Albert Einstein College of Medicine, Bronx, NY.

    Background: Arteriolar hyalinosis (ah) is characterized by deposition of hyaline material in the vascular wall that may be caused by different insults including diabetes, hypertension…
  • 2015 American Transplant Congress

    Membranoproliferative Glomerulonephritis After Kidney Transplantation: A Single Center Experience

    S. Alasfar, N. Carter-Monroe, A. Rosenberg, R. Montgomery, N. Alachkar.

    The Johns Hopkins University, Baltimore, MD.

    Introduction: Membranoproliferative glomerulonephritis (MPGN) is a glomerular disease that frequently leads to ESRD requiring dialysis or kidney transplantation. MPGN recurrence after transplant (rMPGN) often happens…
  • 2015 American Transplant Congress

    The Decreasing Rates of Organ Donation in Trauma Patients: An Analysis of the United Network for Organ Sharing Database

    H. Aziz, T. Jie.

    Transplant Surgery, University of Arizona, Tucson, AZ; Transplant, Surgery, Tucson, AZ.

    INTRODUCTION: The aim of this study was to assess organ donation rates among trauma patients over the years utilizing the national organ donation database (UNOS).METHODS:…
  • 2015 American Transplant Congress

    Role of CMV, BKV, and Immunosupression Non-Adherence in Early and Late De Novo Donor Specific Anti-HLA Antibody Development and Outcomes

    M. Everly,1 L. Rebellato,2 K. Briley,2 A. Maldonado,3 P. Bolin,2 C. Haisch,2 W. Kendrick,4 S. Kendrick,4 C. Morgan,2 R. Harland,2 P. Terasaki.1

    1Terasaki Foundation, Los Angeles; 2East Carolina University, Greenville, NC; 3Vidant Medical Center, Greenville, NC; 4Eastern Nephrology Associates, Greenville, NC.

    This analysis aims to identify appropriate de novo DSA (dnDSA) screening points and delineate the post-transplant (txp) scenarios preceding dnDSA development to aid in clinical…
  • 2015 American Transplant Congress

    Serum Creatinine Is Most Predictive of Graft Loss in Late Antibody Mediated Rejection

    G. Agarwal, D. Diskin, R. Reed, J. Locke, V. Kumar.

    Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.

    Development of acute antibody mediated rejection (AMR) is associated with graft loss and can occur both early (< 3 months) and late (> 3 months)…
  • 2015 American Transplant Congress

    Impact of HLA Antibody Monitoring After Kidney Transplantation

    S. Rao,1 M. Ghanta,1 H. Parekh,2 A. Gillespie,1 I. Lee,1 S. Geier,2 K. Lau,3 S. Karhadkar,3 A. Di Carlo,3 S. Constantinescu.1

    1Nephrology, Temple Univesity School of Medicine, Philadelphia, PA; 2Pathology, Temple Univesity School of Medicine, Philadelphia, PA; 3Surgery, Temple Univesity School of Medicine, Philadelphia, PA.

    The impact of donor specific antibodies (DSA) and optimal therapeutic intervention for DSA in kidney transplant (KT) recipients has been reported with variable results. We…
  • 2015 American Transplant Congress

    Longitudinal eGFR Modelling to Understand Rates of eGFR Decline in Renal Transplantation in the United Kingdom

    R. Pruthi,1 A. Casula,1 R. Hilton,2 R. Ravanan,3 P. Roderick,4 I. Macphee.5

    1UK Renal Registry, Bristol, United Kingdom; 2Guys Hospital, London, United Kingdom; 3Southmead Hospital, Bristol, United Kingdom; 4Southampton University, Southampton, United Kingdom; 5St Georges Hospital, London, United Kingdom.

    Background: The rate of decline in eGFR (slope) has been independently associated with a higher risk of cardiovascular events and all cause mortality in kidney…
  • 2015 American Transplant Congress

    Ideal Versus Total Body Weight Dosing of Rabbit Anti-Thymocyte Globulin Induction Therapy on Patient Outcomes in High Immunological Risk Kidney Transplant

    M. Vacha, J. Gommer, A. Rege, S. Sanoff, D. Sudan, M. Harris.

    Duke University Hospital, Durham, NC.

    BackgroundThe optimal dose of rabbit anti-thymocyte globulin (rATG) induction therapy in high immunological risk kidney transplantation (KTx) lacks consensus and the effect of dosing weight…
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