2015 American Transplant Congress
A Prospective Pilot Study Evaluating the Safety and Efficacy of Everolimus for the Prevention of CMV and BK Viral Infection (BKV) in Broadly Sensitized Kidney Transplant Recipients Following Desensitization With IVIG and Rituximab: Interim Analysis
Introduction: Everolimus, a second generation mTOR inhibitor, may prevent CMV and BKV infection after kidney transplantation. Broadly sensitized patients are at greater risk of viral…2015 American Transplant Congress
Outcomes of Eculizumab (ANTI-C5) Therapy for Treatment of Refractory Antiobdy-Mediated Rejection (ABMR) and Thrombotic Microangiopathy (TMA)
Introduction: ABMR results from DSA binding to donor endothelium initiating the classical complement pathway. This results in the formation of terminal MAC (C5b-C9) complex and…2015 American Transplant Congress
De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch
Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…2015 American Transplant Congress
Association of De Novo Antibody-Mediated Rejection and Increased Hospital Costs Following Kidney Transplant in Immunologically Low-Risk Patients
While antibody-mediated rejection (AMR) is likely the primary cause of kidney transplant (KTx) failure, and its treatment can be considered expensive, incremental center costs for…2015 American Transplant Congress
High Mortality in Diabetic Recipients of High KDPI Deceased Donor Kidneys
Deceased donor (DD) kidney quality is determined using the Kidney Donor Profile Index (KDPI). How best to allocate the high KDPI kidneys (KDPI ≥ 85%)…2015 American Transplant Congress
A Comparison of Alemtuzumab and Antithymocyte Globulin Induction in High-Risk, Non-Sensitized African American Renal Transplant Recipients
Background:Greater than 90% of all kidney transplants(KTx) today receive an induction agent. The choice of a depleting or non-depleting agent is center specific. Alemtuzumab (Alem),…2015 American Transplant Congress
The Role of Immunosuppression on Cardiac Functions of Kidney Transplant Recipients
Transplant Center, Acibadem University, Istanbul, Turkey.
Cardiac disorders are associated with high morbidity and mortality in end-stage renal disease (ESRD).Kidney transplantation is known to increase the survival of dialysis patients by…2015 American Transplant Congress
HCV Treatment in Liver Transplantation: Changes in Center Attitudes and Practices in the DAA Era
Surgery, Johns Hopkins University, Baltimore, MD.
Chronic hepatitis C virus infection (HCV) is the leading indication for liver transplantation (LT) in the US. Safe and effective directly acting antivirals (DAAs) are…2015 American Transplant Congress
Hepatic T Cells Derived from Normothemic Machine Perfused Grafts Contained More Regulatory T Cells and Fewer Proinflammatory Cytokines Producing T Cells Than Those from Cold Storage Grafts
Background & aim:In liver transplantation, ischemia reperfusion (I/R) injury is associated with an inflammatory response affecting graft and patient outcomes. Ex-vivo normothermic machine perfusion (NMP)…2015 American Transplant Congress
Assessment of Actual Pediatric Organ Donation Potential: Neurologic and Circulatory Determination of Death at a Children's Hospital
BACKGROUND AND OBJECTIVES: Organ donation after circulatory determination of death (DCDD) is increasing. DCDD offers potential for additional abdominal organ donation. We evaluated all dying…
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