ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Month 48 Follow-Up Results of HERAKLES Trial on Three Different Treatment Regimen and Switching Off Behaviour in De Novo Renal Transplant Patients

    W. Arns,1 K. Budde,1 C. Sommerer,1 O. Witzke,1 M. Guba,1 J. Jacobi,1 B. Vogt,3 P. Reinke,1 I. Hauser,1 R. Stahl,1 T. Rath,1 D. Baeumer,2 M. Porstner,2 M. Zeier,1 F. Lehner,1 V. Kliem.1

    1Herakles Study Group, Germany; 2Novartis, Pharma, Germany; 3Herakles Study Group, Switzerland.

    Aim: To compare switching off 3 different immunosuppressive (IS) regimen 4years after renal transplantation (Tx).Methods: 802 patients (pts) were included in this prospective, open-label, randomized,…
  • 2015 American Transplant Congress

    Prognostic Relevance of Rejection Episodes Detected Within the First 3 Weeks After Kidney Transplantation

    V. Arelin,1 H. Schrem,2 F. Lehner,2 W. Gwinner,1 H. Haller,1 M. Schiffer.1

    1Division of Nephrology and Hypertension, Department of Medicine, Hannover Medical School, Hannover, Lower Saxony, Germany; 2General, Visceral and Transplant Surgery, Hannover Medical School, Hannover, Lower Saxony, Germany.

    Background:The relevance of cellular rejection events detected in the early phase after kidney transplantation for graft survival and function remains to be elucidated. Especially the…
  • 2015 American Transplant Congress

    The Negative Impact of Hepatitis C Infection (HCV+) On Orthotopic Liver Transplantation (OLT) for Hepatocellular Carcinoma (HCC)

    A. Daoud,1,3 L. Teeter,2 E. Graviss,2 S. Burroughs,1 A. Gaber.1

    1Transplant Center, Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; 3Internal Medicine Department, Cairo University Medical school, Cairo, Egypt.

    Background: HCC is commonly associated with viral infections such as HCV & HBV.Aim: To determine whether Hepatitis viral status has impact on survival after OLT…
  • 2015 American Transplant Congress

    Recurrence of Hepatocellular Carcinoma After Transarterial Chemoembolization (TACE) Alone and TACE in Combination With Other Treatment Modalities

    J. Balogh, A. Islam, A. Saharia, H. Monsour, S. Gordon Burroughs, M. Weiner, A. Gaber, R. Ghobrial.

    General Surgery, Houston Methodist Hospital, Houston, TX.

    AIM:Treatment of hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) can help downstage tumors prior to orthotopic liver transplantation (OLT); however, there is a risk of…
  • 2015 American Transplant Congress

    Medication Adherence in Adolescents With Kidney Transplant and Chronic Kidney Disease: Patient/Caregiver Report Vs. Provider Perception

    C. Pruette,1 T. Brady,1 S. Mendley,2 B. Fivush,1 S. Tuchman,3 A. Green,1 M. Eakin,1 K. Riekert.1

    1Johns Hopkins University School of Medicine, Baltimore, MD; 2University of Maryland School of Medicine, Baltimore, MD; 3Children's National Medical Center, Washington, DC.

    Background: Medication adherence in adolescent kidney transplant (KT) recipients is poor, with non-adherence (NA) ranging from 5-71%, and NA is associated with poor graft survival.…
  • 2015 American Transplant Congress

    Early Relapse of Atypical HUS Following ABO Incompatible Living Related Paediatric Renal Re-Transplant Successfully Treated With Eculizumab

    J. Stojanovic,1 A. Adamusiak,2 N. Sebire,3 S. Marks,1 N. Mamode.2

    1Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom; 2Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; 3Department of Histopathology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom.

    Background. The female patient presented at 3 years of age with clinical features suggestive of aHUS confirmed genetically as complement factor I mutation (heterozygous for…
  • 2015 American Transplant Congress

    Legal Issues in Domino Liver Transplantation in Germany

    H. Schmidt,1 A. Barreiros,2 H. Schlitt,2 T. Gutmann.3

    1Klinik für Transplantationsmedizin, Universitätsklinikum Münster, Münster, Germany; 2Universitätsklinikum Regensburg, Regensburg, Germany; 3Rechtswissenschaftliche Fakultät, Westfälische Wilhelms-Universität Münster, Münster, Germany.

    TTR-amyloidosis (FAP) is caused by TTR variants expressed and secreted by the liver. Therefore, liver transplantation was introduced as therapeutic option to prevent or limit…
  • 2015 American Transplant Congress

    The Effects of Donor Specific Anti- Human Leukocyte Antigen Antibodies Late After Heart Transplantation

    M. Kittleson, J. Patel, F. Liou, S. Siddiqui, A. Fong, M. Johnson, D. Chang, L. Czer, F. Esmailian, N. Reinsmoen, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: The development of anti-HLA antibodies following heart transplantation has been associated with poor outcomes, including lower survival and increased risk for the development of…
  • 2015 American Transplant Congress

    Survival Benefit of Liver Transplant Among HIV+ Waitlist Candidates

    C. Durand,1 S. Gustafson,2 J. Locke,3 J. Snyder,2 B. Shelton,3 R. Reed,3 P. MacLennan,3 S. Mehta,3 A. Nellore,3 D. Segev.1,2

    1Johns Hopkins University, Baltimore, MD; 2Scientific Registry of Transplant Recipients (SRTR), CDRG, Minneapolis, MN; 3University of Alabama, Birmingham, Birmingham, Al.

    Liver failure is the most common cause of non-AIDS related death among HIV+ patients, primarily due to high prevalence of co-infection with hepatitis C (HCV)…
  • 2015 American Transplant Congress

    Beneficial Effects of Controlling Peritransplant Inflammation in Total Pancreatectomy With Islet Autotransplantation: A Single Center Experience With Large Cohort of Patients

    M. Takita,1 M. Kanak,2 R. Shahbazov,1 G. Yoshimatsu,1 M. Lawrence,1 A. Dabous,3 P. Kim,3 N. Onaca,3 B. Naziruddin,3 M. Levy.3

    1Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; 2Institute for Biomedical Studies, Baylor University, Waco, TX; 3Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.

    Background: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective surgical treatment for patients with intractable chronic pancreatitis (CP). We recently reported that significant mass…
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