2015 American Transplant Congress
The Role of an Intragraft Vascularized Bone Marrow Niche in Establishing Mixed Chimerism and Allograft Acceptance
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.
Background: Vascularized composite allotransplantation has emerged as a viable treatment option for patients with devastating tissue loss not amenable to traditional reconstructive techniques. Different from…2015 American Transplant Congress
Infusion of Human Factor 7a Restores Circulating Platelets and Prevents TMA in Pig-to-Baboon Liver Xenotransplantation
Background We sought to determine the effects of exogenous administration of human coagulation factors in a pig-to-baboon model of liver xenotransplantation (LXT).Methods LXT was performed…2015 American Transplant Congress
The Immunogenic Perlecan Fragment LG3 Is Released Through Apoptotic Extracellular Vesicles Downstream of Caspase-3 Activation
LG3, a C-terminal fragment of perlecan, has been implicated in aggravation of renal allograft rejection and vascular injury. LG3 is known to be produced at…2015 American Transplant Congress
Combined Anti-IL6R and CTLA4Ig Therapy Attenuates Recall Alloantibody Responses in a Mouse Model of HLA Sensitization
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
[bald]Background[/bald] We previously reported that IL-6 inhibition by anti-IL6R antibody (mMR16-1) or CD28 pathway inhibition using CTLA4Ig (abatacept) reduced recall alloantibody responses in a mouse…2015 American Transplant Congress
Racial Disparities in Preemptive Kidney Transplant Referrals in Georgia: Data from the RaDIANT Community Study
PurposeAccess to kidney transplantation (KTx) before initiation of dialysis is associated with improved patient and graft survival, enhanced quality of life, and decreased hospital readmissions…2015 American Transplant Congress
National Outcomes of Kidney Transplantation from Diabetic Donors
Despite limited outcomes data, kidneys from diabetic donors are being increasingly used in the USA. To compare outcomes in recipients of kidneys from diabetic versus…2015 American Transplant Congress
Impact of Type of Tacrolimus Assay on Therapeutic Drug Monitoring: Need for Standardization
Internal Medicine/Nephrology, Washington University School of Medicine, St. Louis, MO.
Background: Multiple assays are available for measuring tacrolimus (FK) levels and these are not currently standardized. A designated laboratory transitioned their FK assay from Enzyme…2015 American Transplant Congress
Return to Work and Occupational Infection Risks in Transplant Recipients
Background: Counseling is commonly provided to transplant recipients who are planning to return to work, regarding potential infection risks in the workplace. However, the nature…2015 American Transplant Congress
Pre-Transplant Desensitization Protocol and Cancer Risk in Kidney Transplantation
Introduction: Desensitization (DS) in kidney transplant is a current therapy for all cause of incompatible living donor kidney transplants (LDKT). The impact in cancer risk…2015 American Transplant Congress
The Impact of Ischemia/Reperfusion Injury On Liver Allografts from Deceased After Cardiac Death Versus Deceased After Brain Death Donors
Background and Aims:The shortage of appropriate organs for transplantation has led to the use of organs from donors after cardiac death. The pathophysiologic processes associated…
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