2015 American Transplant Congress
Inhibition of RhoA Pathway-Related Macrophage Functions Abrogates Chronic Rejection of Cardiac Allograft
Objective. Chronic rejection remains the main obstacle in the long-term success of organ transplantation. The long-term survival of allografted hearts is limited by a progressive…2015 American Transplant Congress
Real-Time Measurements of Tissue Oxygen Microtension as a Marker of Bile Duct Viability in Liver Transplantation
General Surgery, HU Reina Sofía, Córdoba, Spain.
Aims: To evaluate bile duct viability by assessing its microvascular quality using an innovative real-time oxygen tension device by testing different areas in both donor…2015 American Transplant Congress
Propensity Score-Weighted Analysis of Induction Therapies in Live Donor Kidney Transplantation in Modern Immunosuppression Era
1Medicine, UTSW, Dallas, TX; 2Clinical Sciences, UTSW, Dallas, TX; 3Surgery, UTSW, Dallas, TX.
Background: Induction therapy with interleukin-2 receptor antagonist (IL2-RA) is recommended as a first line agent in living donor renal transplantation (LRT). However, use of IL2-RA…2015 American Transplant Congress
Hybrid-Natural Orifice Transluminal Endoscopic Surgery (NOTES) for Laparoscopic Donor Nephrectomy Offers Better Postoperative Pain, Cosmesis and Surgical Outcomes Than Transumbilical Single Site Surgery
Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Laparoendoscopic single site donor nephrectomy (LESSDN) via the umbilicus has been our standard care for living donors. Although we have previously reported better cosmetic…2015 American Transplant Congress
Virus Induced CD28 Down-Regulation as a Potential Driver of Costimulation Blockade Resistant Rejection
1Surgery, Emory University, Atlanta, GA; 2Surgery, Duke University, Durham, NC.
Belatacept, a B7-specific fusion protein, blocks CD28-B7 costimulation and prevents kidney allograft rejection. However, it is ineffective in a sizable minority of patients. Although T…2015 American Transplant Congress
Norovirus Infection in Renal Transplant Recipients – Clinical Severity and Genotype Identification
Introduction: Norovirus (NoV) is increasingly recognized as causative agent of gastro-enteritis in renal transplant recipients.Methods: We performed a retrospective study (2003-2012) to investigate the clinical…2015 American Transplant Congress
Dramatic Improvements in Racial Disparities in Kidney Transplant Outcomes in the US
1Johns Hopkins, Baltimore; 2Duke University, Durham.
Earlier studies reported inferior graft survival in black transplant recipients. We examined 20-year trends in outcomes to determine whether racial disparities improved over time. METHODS:…2015 American Transplant Congress
Effector T Cell Migration to Pancreatic Islet Allografts Is Dependent On Donor Antigen Recognition and Not Gαi Chemokine Signaling
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA.
Infiltration of the graft with host effector T cells after transplantation is a key step in the pathogenesis of both acute and chronic rejection. Recent…2015 American Transplant Congress
Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?
The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…2015 American Transplant Congress
Impact of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters After Living Donor Liver Transplantation
The present study investigated the impact of pretransplant sarcopenia on survival and sequential changes in sarcopenic parameters in patients undergoing living donor liver transplantation (LDLT).…
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