Am J Transplant, Volume 5, Suppl 3 Archives - Page 153 of 170 - ATC Abstracts

2015 American Transplant Congress
Inverse Monocytic Subset Profile in Blood and Tissue During Heart Transplant Rejection
T. van den Bosch,¹ M. Kraaij,¹ K. Caliskan,² A. Constantinescu,² O. Manintveld,² P. Leenen,³ C. Baan,¹ M. van Groningen,⁴ A. Rowshani.¹
¹Department of Internal Medicine, Section Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; ²Department of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands; ⁴Department of Pathology, Erasmus Medical Center, Rotterdam, Netherlands.
Introduction: Increased monocytic infiltration of heart transplant tissue is documented during acute rejection. It is still unclear how changes in circulating monocyte pool relate to…
2015 American Transplant Congress
Evaluation of the Gastrointestinal Tract as a Potential Route of Primary Polyomavirus Infection
G. Huang,¹ G. Zeng,² Y. Huang,² P. Randhawa.²
¹Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Detection of Polyomavirus(Py) DNA in metropolitan river water worldwide has led to the suggestion that primary viral infection can occur by the oral route. The…
2015 American Transplant Congress
Proximal Tubular Dysfunction Is Common After the First Year of Kidney Transplantation
G. Ensergueix,¹ J. Allard,¹ F. Saint-Marcoux,² B. Marin,³ S. Bodeau,² J.-C. Aldigier,¹ P. Marquet,² M. Essig.¹
¹Nephrology, Dialysis, Transplantation, University Hospital, Limoges, France; ²Pharmacology, Toxicology, University Hospital, Limoges, France; ³Epidemiology, Biostatistics, Methodology, University Hospital, Limoges, France.
Background: After the initial period of kidney transplantation, the prevalence of proximal tubular dysfunction (PTD) and its consequences are unknown. The aim of this study…
2015 American Transplant Congress
The Outcomes of Second Transplantation in Recurrent IgA Nephropathy
C. Baek,¹ H. Kim,¹ W. Yang,¹ W. Huh,² Y. Kim,³ J. Yang,⁴ D. Han,⁵ S.-K. Park.¹
¹Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; ²Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; ³Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; ⁴Transplantation Center, Seoul National University Hospital, Seoul, Republic of Korea; ⁵Department of Surgery, Asan Medical Center, Seoul, Republic of Korea.
BackgroundRecurrence of original glomerulonephritis is an important cause of graft loss. In some studies, histologic recurrence of IgA nephropathy (IgAN) occurs in 60% after 1st…
2015 American Transplant Congress
A 10 Min “No-Touch” Time – Is It Enough in DCD? A DCD Animal Study
M. Sereinigg,¹ V. Stadlbauer,² T. Seifert-Held,³ F. Iberer,¹ P. Stiegler.¹
¹Department for Transplant Surgery, Medical University Graz, Graz, Austria; ²Department for Gastroenterology and Hepatology, Medical University Graz, Graz, Austria; ³Department for Neurology, Medical University Graz, Graz, Austria.
Introduction: DCD is under investigation due to the lack of human donor organs. Required times of cardiac arrest vary between 75 seconds and 27 min…
2015 American Transplant Congress
Detection of Donor Specific HLA-Ab (DSA) Against Native HLA Molecules Expressed On Donor Cell Surface to Eliminate False Positive DSA in Luminex Single Antigen Beads (LMX-SAB)
G. Chen, L. Lin, D. Tyan.
Pathology, Stanford University, Palo Alto, CA.
Introduction:The LMX-SAB has been extensively used for DSA virtual crossmatch (VXM) to predict actual crossmatch (AXM). The extreme pH and harsh chemical reaction conditions used…
2015 American Transplant Congress
Transplant Glomerulitis in Allograft Kidneys Is Correlated With Antibody-Mediated Rejection
W. Xu, T. Deng.
Department of Pathology, MedStar Georgetown University Hospital and Washington Hospital Center, Washington.
Background: Antibody-mediated rejection manifests with glomerular and peritubular capillary inflammation, transplant glomerulopathy. Transplant glomerulitis is an increasingly recognized lesion in renal transplant biopsies, characterized by…
2015 American Transplant Congress
Intimal Arteritis Associated With Subsequent Graft Dysfunction in ABO-Incompatible Kidney Transplantation
D. Toki,¹ H. Iahida,¹ M. Okumi,¹ T. Shimizu,¹ M. Inui,¹ K. Omoto,¹ H. Shirakawa,¹ K. Unagami,¹ K. Honda,² J. Koike,³ K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Pathology, Tama Hospital, Kanagawa, Japan.
Purpose: The diagnosis of acute antibody-mediated rejection (ABMR) is according to following all three evidences: 1) histologic evidence , 2) evidence of interaction with vascular…
2015 American Transplant Congress
Effect of Antibody Mediated Rejection on Long-Term Renal Allograft Function
M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.
Transplant Institute, Tulane University, New Orleans, LA.
Historically we had poor understanding of chronic rejection attributing it to hypertension and non-compliance. However in the last decade we have begun to understand the…
2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
P. Vaitla, H. Bohorquez, A. Cohen, A. Cruz, U. Patel, S. Anders, C.-S. Catherine, A. Moiz, S. Guisti, I. Carmody, G. Loss, D. Bruce, T. Reichman, J. Garces.
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…