2015 American Transplant Congress
Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities
Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…2015 American Transplant Congress
Factors Associated With Rehospitalization and High Cost Among Health Plan Members Receiving Kidney Transplants
PurposeAims were to develop a claims-based algorithm to identify kidney transplant cases and to examine clinical and economic outcomes among health plan members undergoing kidney…2015 American Transplant Congress
Effects of Heart and Lung Co-Transplantation Across a Full MHC Barrier in Miniature Swine
Background: We have previously shown that tolerance of heart allografts across a full MHC barrier can be induced in miniature swine after a 12-day course…2015 American Transplant Congress
Differential Expression and Function of ASC and Nlrp3 Inflammasome Adaptors in Hematopoietic Stem Cells (HSCs)
Medicine, University of California San Diego, San Diego, CA.
HSCs are activated by pattern recognition receptors (PRRs), which might provide novel targets for improved engraftment. How PRRs affect HSC engraftment after BM transplantation is…2015 American Transplant Congress
Current Status of US Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Intestine Transplant Registry
The purpose of this study is to analyze the current status of US intestinal transplantation (IT). As of 9/19/2014, 2441 IT have been performed in…2015 American Transplant Congress
Outcome of Renal Sparing Protocol in a Cross-Sectional Analysis After Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Calcineurin inhibitors (CNIs) are the mainstay of immunotherapy after heart transplantation. Unfortunately CNIs are associated with renal dysfunction due to nephrotoxic side effects. The…2015 American Transplant Congress
Comparison of Risk Factors and Outcomes of Daptomycin-Susceptible and -Nonsusceptible Enterococcus Infections in Liver Transplant Recipients
University of Virginia, Charlottesville, VA.
PurposeDaptomycin (DAP) has become an important therapeutic agent to treat infections due to vancomycin-resistant Enterococcus faecium (VRE), including in liver transplant recipients (LTRs); however, DAP-nonsusceptible…2015 American Transplant Congress
Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism in Nonhuman Primates
Transplant Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Background: We have previously reported a successful induction of mixed chimerism and the long-term acceptance of renal allografts in MHC-mismatched nonhuman primates. In this study,…2015 American Transplant Congress
Human Hematopoietic Chimeric Cells as a Novel Approach for Tolerance Induction After Transplantation
Background: Cellular therapies represent a new promising approach for transplant tolerance induction. One of the methods for immune response modulation in solid organ and vascularized…2015 American Transplant Congress
Efficacy, Safety and Pharmacokinetics of Once-Daily, MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus (Prograf®) in De Novo Kidney Transplant Recipient Sub-Groups: A 2 Year Phase 3 Randomized, Double-Blind, Double-Dummy, Trial
Differences in tacrolimus (tac) metabolism are evident in certain populations; in particular, lower tac bioavailability has been shown in females and black kidney transplant recipients…
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