ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Impact of Alemtuzumab and Basiliximab Induction On Patient and Graft Survival in Single Lung Transplant Recipients

    Y. Furuya,1 S. Jayarajan,2 S. Taghavi,2 V. Ambur,2 F. Cordova,3 N. Patel,3 Y. Toyoda.4

    1Internal Medicine, Temple University Hospital, Philadelphia, PA; 2Surgery, Temple University Hospital, Philadelphia, PA; 3Pulmonary & Critical Care, Temple University Hospital, Philadelphia, PA; 4Cardiothoracic Surgery, Temple University Hospital, Philadelphia, PA.

    PurposeTo evaluate the impact of alemtuzumab, basiliximab and no induction therapy on patient survival and chronic rejection.Methods3242 adult single lung transplantation from 2006 to 2013…
  • 2015 American Transplant Congress

    Obesity: A Major Risk Factor for Wound and Parietal Complications in Renal Transplantation

    H. Andrade, W. Nahas, R. Kato, K. Yamaçake, H. Kanashiro, I. Antonopoulos, A. Bull, R. Falci, A. Piovesan.

    Division of Urology, Renal Transplantation Unit, University of Sao Paulo, Sao Paulo, Brazil.

    Purpose: The increase of obesity among patients with end-stage renal disease poses a major challenge for urologists and nephrologists. Many centers set an upper limit…
  • 2015 American Transplant Congress

    Acoustic Radiation Force Impulse Measurement in Renal Transplantation

    J. Lee,1 J. Lee,1 A.-l. Lee,2 B. Ma,3 Y. Oh,4 K. Huh,1 M. Kim,1 S. Kim,1 Y. Kim,1 D. Joo.1

    1Department of Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Department of Surgery, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 3Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea; 4Department of Radiology, Yonsei University Health System, Seoul, Republic of Korea.

    BackgroundAllograft biopsy is the definitive diagnostic methods for evaluation of renal dysfunction, but there is always the risk of complications. Efforts to develop a notable…
  • 2015 American Transplant Congress

    Potential Urine Protein Biomarkers for Kidney Transplantation Dysfunction Through Quantitative Proteomics

    T. Sigdel,1 N. Salomonis,2 C. Nicora,3 J. He,3 W.-J. Qian,3 D. Camp,3 M. Sarwal.1

    1UCSF, San Francisco, CA; 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3Pacific Northwest National Laboratory, Richland, WA.

    Introduction: Inability to effectively monitor transplant injuries leads to immune and non-immune mediated graft dysfunction. A non-invasive tool to monitor such injuries is an unmet…
  • 2015 American Transplant Congress

    ABCB1 Haplotypes, Sex, Calcineurin Inhibitors and Lipid Profiles Post-Renal Transplant

    C. Meaney,1,2 R. Venuto,3 D. Brazeau,4 J. Consiglio,5 L. Cooper,1 G. Wilding,5 K. Tornatore.1,2,3

    1NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY; 2School of Pharmacy, Buffalo, NY; 3Medicine, School of Medicine, Buffalo, NY; 4University of New England College of Pharmacy, Portland, ME; 5Biostatistics, School of Public Health, University at Buffalo, Buffalo, NY.

    Purpose: Hyperlipidemia is common in renal transplant recipients (RTR) during calcineurin inhibitor (CNI) immunosuppression. P-glycoprotein (P-gp) is an efflux transporter encoded by ABCB1 that modulates…
  • 2015 American Transplant Congress

    Somatostatin (Eumedica®) Infusion Allows Modulating Graft Flows and Gradients in Liver Transplantation. Results of a Randomized, Double Blind, Placebo Controlled Trial

    R. Troisi,1 A. Croo,1 E. Codarin,3 E. De Wolf,1 J. Van Limmen,4 G. Antoniali,3 B. Heyse,4 L. De Baerdemaeker,4 I. Colle,5 G. Tell,3 M. Sainz-Barriga.1,2

    1General Hepatobiliary Surgery Liver Transplantation Service, Ghent University Hospital Medical School, Ghent, Belgium; 2Digestive Surgery & Liver Transplantation, University of Tours, Tours, France; 3Medical & Biological Sciences, University of Udine, Udine, Italy; 4Anesthesiology, Ghent University Hospital Medical School, Ghent, Belgium; 5Gastroenterology, Ghent University Hospital Medical School, Ghent, Belgium.

    Background: Somatostatin (SST) infusion decrease portal pressure in acute variceal bleeding in cirrhotic patients. Despite liver transplantation (LTx), recipients with portal hypertension (PHT) display different…
  • 2015 American Transplant Congress

    Immune Phenotyping of Peripheral Blood Samples from the CTOT-10 Belatacept Study

    Y. Suessmuth,1 L. Stempora,1 B. Johnson,1 J. Cheeseman,1 Y. Morrison,4 N. Bridges,4 D. Ikle,5 S. Tomlanovich,3 P. Stock,3 R. Mannon,2 K. Newell,1 C. Larsen,1 A. Mehta.1

    1Emory Transplant Center, Atlanta; 2University of Alabama, Birmingham; 3University of California San Francisco, San Francisco; 4NIAID/ NIH, Bethesda; 5Rho, Chapel Hill, NC.

    The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…
  • 2015 American Transplant Congress

    Transplant Glomerulopathy in a Novel Model of Chronic Antibody Mediated Rejection Is Associated With DSA and Glomerular IgM

    S. Panzer,1 S. Reese,1 N. Wilson Schlei,1 W. Zhong,2 A. Djamali.1

    1Medicine, University of Wisconsin Madison, Madison, WI; 2Pathology, University of Wisconsin Madison, Madison, WI.

    PurposeChronic active antibody mediated rejection (cAMR) and transplant glomerulopathy (TG) are major determinants of long-term allograft survival. However, the contribution of DSA and glomerular immunoglobulins…
  • 2015 American Transplant Congress

    Native Americans and Post-Kidney Transplant Follow-Up: Lower in Quantity and Quality?

    S. Stith,1 F. Barrantes.2

    1Department of Economics, University of New Mexico, Albuquerque, NM; 2Renal Medicine Associates/Presbyterian Transplant Center, Albuquerque, NM.

    Background: Native Americans have been shown to face decreased access to waitlisting and transplantation.They appear to have similar short-term survival prospects post-transplant to those of…
  • 2015 American Transplant Congress

    Emerging Strategies to Screen Kidney Offers Based on the Kidney Donor Profile Index (KDPI)

    D. Stewart,1 A. Kucheryavaya,1 G. Boyle,1 R. Metzger,2,3 M. Aeder,4 R. Formica.5

    1UNOS, Richmond, VA; 2Florida Hosp, Orlando, FL; 3Translife, Orlando, FL; 4Univ Hosp Case Med Ctr, Cleveland, OH; 5Yale Univ, New Haven, CT.

    Background: In the Organ Procurement and Transplantation Network's (OPTN) new kidney allocation system, kidney offers are screened by setting for each candidate a maximum acceptable…
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