2015 American Transplant Congress
Ischemic Cholangiopathy Following Liver Transplantation from Donation After Circulatory Death Donors: Role of Tissue Plasminogen Activator Flush
Background: Formation of microthrombi within the peribiliary arterial plexus causing necrosis of biliary epithelium may be responsible for ischemic cholangiopathy (IC) after donation after circulatory…2015 American Transplant Congress
Predicting Survival of Deceased Donor Kidneys from Children Under Ten
University of Chicago, Chicago, IL.
Background: The United Network for Organ Sharing (UNOS) has adopted a new allocation algorithm that uses a Kidney Donor Profile Index (KDPI) based on 10…2015 American Transplant Congress
Final Results from the BENEFIT-EXT Trial: A 7 Year Follow-Up of Belatacept Treated Patients
Background: At 3 and 5yrs post-transplant, BENEFIT-EXT showed a renal function benefit and consistent safety in belatacept (bela) treated pts vs cyclosporine (CsA). Final 7…2015 American Transplant Congress
Eomes-Expressing CD8+ T Cells and Th17 Cells Mediate Costimulatory Blockade-Resistant Allograft Rejection in Mice
The etiology of costimulatory blockade-resistant allograft rejection remains unclear. Therefore, the purpose of this study was to evaluate the responsiveness of distinct CD4+ and CD8+…2015 American Transplant Congress
A Gene Expression Assessment for Improving Disease Activity and Stage in Heart ABMR
Paris Transplant Group & ATAGC, Paris - Edmonton, France.
BackgroundABMR is a major cause of heart transplant failure. The diagnosis of ABMR in heart transplantation is based on the 2013 ISHLT pAMR classification. We…2015 American Transplant Congress
Gender Disparity in Infections After Kidney Transplantation
BACKGROUND: Female gender has been suggested as a risk factor for infection after kidney transplant (KT). Preliminary studies have reported that sex hormones such as…2015 American Transplant Congress
Pre-Transplant Donor Specific Antibody With Negative Flow-Crossmatch Was Related to Higher Acute Rejection But Not to Poor Graft Survival
Background: DSA have been associated to lower graft survival and a higher humoral rejection rate, but there is a concern about the clinical impact of…2015 American Transplant Congress
Morphometric Age as a Predictor of Survival Following Kidney Transplantation
1University of Michigan, Ann Arbor, MI; 2Case Western Reserve University, Cleveland, OH.
INTRODUCTION: Better measures of pre-operative risk stratification are needed in kidney transplantation. Analytic morphomics, which utilizes pre-operative imaging, has been shown to objectively assess mortality…2015 American Transplant Congress
Live Donor Liver Transplantation With Older (>50years) Vs Younger (<50years) Donors: Does Age Matter?
Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Introduction: The risks of living donor liver transplantation (LDLT) with older donors remains controversial and many centers avoid using live donors ≥45 years of age.…2015 American Transplant Congress
miRNA-181 Promotes Graft Prolongation by Plasmacytoid Dendritic Cells By Increasing T Regulatory Cells and Decreasing B Cells as Revealed By Cytometry By Time-Of-Flight
1Surgery, Stanford University, Stanford, CA; 2Pediatrics, UCSF, San Francisco, CA.
Liver allografts are well tolerated and other solid organ allografts, when transplanted concurrently with livers, show improved outcomes. However, the mechanisms underlying hepatic tolerance have…
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