2015 American Transplant Congress
Can Gene-Expression Profiling Score Help Explain the Adverse Clinical Outcomes Seen in Gender-Mismatched Heart Transplants?
Background: Gene-expression profiling (GEP) testing, in conjunction with clinical assessment, is an established laboratory test intended to aid in the identification of acute cellular rejection…2015 American Transplant Congress
Boosting the Adaptive Immune Response Prevents the High Incidence of Herpes Zoster After Lung or Heart Transplantation
Purpose Primary varicella zoster virus (VZV) infection causes varicella and lifelong latent infection in ganglia from which it may reactivate leading to herpes zoster (HZ).…2015 American Transplant Congress
Can Post-Transplant C-Peptide Be Used as an Indicator of Pancreas Graft Failure?
Background: The OPTN Pancreas Transplantation Committee is attempting to define pancreas graft failure and performed a study to determine if C-peptide corresponds to pancreas graft…2015 American Transplant Congress
Screening Recipients of Increased Risk Donor Organs: A Multicenter Study
Purpose: Policy mandates post-transplant (tx) evaluation of recipients of increased risk donor organs (ROIRDO). PHS guidelines recommend that screening include HIV & hepatitis C virus…2015 American Transplant Congress
Non-Invasive Panel of MicroRNAs Predict Long-Term Outcomes Post-Kidney Transplantation
1Surgery and Pathology, UVA, Charlottesville, VA; 2VCU, Richmond, VA.
Background. Currently available methods for evaluating kidney graft function post-transplantation (KT) are either ineffective or inaccurate (e.g., serum creatinine) or highly invasive (e.g., biopsies). We…2015 American Transplant Congress
Changes in Health Related Quality of Life (HRQOL) in Pediatric Liver Transplant (LT) Recipients During Protocolized Immunosuppression Withdrawal (ISW): The iWITH Trial
ISW may limit medication-related comorbidities but intensive monitoring and unexpected rejection episodes may compromise HRQOL. We studied longitudinal HRQOL in pediatric LT recipients undergoing ISW…2015 American Transplant Congress
The Selection Process for Total Artificial Heart
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Heart failure patients with severe biventricular failure who are candidates for heart transplant are considered for Total Artificial Heart (TAH) support. These patients may…2015 American Transplant Congress
Failure to Account for Critical Candidate Characteristics Significantly Biases Kidney Transplant Center Report Cards Measuring Time to Transplant
1Surgery, Montefiore Medical Center, Bronx, NY; 2Medicine, Cleveland Clinic, Cleveland, OH.
Kidney transplant rate is proposed to be integrated into the new composite metric to evaluate center performance. Current methods adjust for PRA, blood type, re-transplantation,…2015 American Transplant Congress
Association Between Histological Abnormalities in Time-Zero Renal Biopsies and Post-Donation eGFR in Live Donors
Time-zero biopsies (T0-RBx) of live-donor kidneys may reveal histological abnormalities at the time of organ recovery. The association between T0-RBx and subsequent kidney function in…2015 American Transplant Congress
Comparison of T Regulatory (Treg) Cell Function Pre- and Post-Lung Transplantation Shows a Major Negative Impact of Immunosuppression on Treg Function
Aim: Clinical lung Tx recipients do not have sustained long-term survival outcomes comparable to that of other recipients of solid organ allografts, despite generally comparable…
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