2015 American Transplant Congress
The Impact of Metabolic Syndrome and Prevalent Liver Disease on Living Donor Liver Transplantation: A Pressing Need to Expand the Pool
Background and Aims: Organ shortage has been the ongoing obstacle to expand liver transplantation world-wide. Living donor liver transplantation (LDLT) was hoped to improve this…2015 American Transplant Congress
Preserved Kidney Volume in Living Kidney Donors: Correlation With 2 Year Renal Function Using CKD-EPI Equation to Predict Remaining GFR
1Indiana University; 2Ohio State University, Columbus.
Background: The aim of our study was to evaluate whether preserved kidney volume correlates with donor renal function at 2-years post-donation using the CKD-EPI eGFR…2015 American Transplant Congress
Quantifying Altruism in Kidney Donors: How Good Are the Current Scales?
The decision to become a living kidney donor is complicated and altruism is certainly what drives the majority of organ donors. Unfortunately, there are no…2015 American Transplant Congress
Lung Transplantation from Donors With Kidney Disease
Duke University Medical Center, Durham, NC.
Background:Various donor characteristics are associated with decreased survival following single (SLT) or bilateral (BLT) lung transplantation. No current studies exist regarding use of lungs from…2015 American Transplant Congress
Excellent Outcomes With Kidney Transplantation for Patients ≥70 Years of Age
BackgroundOur aim was to determine the outcomes following kidney transplantation in recipients ≥70 years of age at the time of transplantation.Materials and MethodsWe analyzed data…2015 American Transplant Congress
Pro-Inflammatory Actions of New Non-HLA Antibodies Targeting Protease-Activated Receptor (PAR-1)
Microvascular endothelium is major target for antibodies directed against HLA and non-HLA antigens. Functional antibodies targeting G-protein coupled receptors (GPCRs) such as AT1R or ETAR…2015 American Transplant Congress
Pharmacogenetic Variation in Renal Calcineurin Inhibitor (CNI) Metabolism and the Response of Allograft-Derived Proximal Tubule Cells
Background: Multiple studies have demonstrated the importance of genetic variation in CYP3A5 and ABCB1 for calcineurin inhibitor (CNI) disposition and CNI-related nephrotoxicity. Renal CNI metabolism…2015 American Transplant Congress
Accurate Prediction of High-Resolution HLA-A, -B, -C, -DRB1 and -DQB1 Typing and Low-Resolution HLA-DQA1 Typing by Haplotype Analysis
Aim: Allele-specific HLA antibodies are commonly detected by Luminex single antigen bead assays in solid organ transplant recipients. However, high-resolution HLA typing for deceased donors…2015 American Transplant Congress
Inhibition of mTOR Modulates SLPI Expression: A Potential Role in Kidney Transplant Patients
Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor secreted by inflammatory and epithelial cells. It functions as an endogenous immunomodulatory, with antiinflammatory and…2015 American Transplant Congress
Clinical and Biochemical Results of BK Virus Nephropathy in Kidney Allograft Recipients
BK virus (BKV) nephropathy has emerged as a significant cause of graft dysfuction in kidney allograft recipients after using powerful immunosupressive treatment protocols in recent…
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