ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Predicting Renal Recovery After Liver Transplant With Severe Pretransplant Sub-Acute Kidney Injury: The Impact of Warm Ischemic Time

    H. Laskey, T. Nydam, A. Wiseman, S. Biggins.

    Hepatology, Transplant Surgery and Nephrology, Univ. Colorado, Aurora, CO.

    Identification of which liver transplant candidates with severe kidney injury can have full recovery of renal function after liver only transplant is difficult. Avoiding unnecessary…
  • 2015 American Transplant Congress

    Live Donor Vs Deceased Donor Liver Transplantation Results in Identical Outcome in Recipients With Acute Liver Failure – An Important Choice for Critical Ill Patients

    N. Goldaracena, G. Sapisochin, J. Echeverri, M. Kaths, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, G. Levy, A. Ghanekar, E. Renner, D. Grant, M. Selzner.

    Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Introduction: Live donor liver transplantation (LDLT) is a valid alternative to deceased donor liver transplantation (DDLT) in patients suffering from acute liver failure (ALF). Rapid…
  • 2015 American Transplant Congress

    Quantifying Risk of ESRD in Live Kidney Donors

    A. Massie, A. Muzaale, X. Luo, D. Segev.

    Johns Hopkins, Baltimore.

    Among live kidney donors higher overall risk of ESRD has been shown in African-Americans and men. However, individual risk of ESRD has not been quantified.METHODS:…
  • 2015 American Transplant Congress

    Correlates and Consequences of Gout Among Living Kidney Donors

    N. Lam,1 A. Garg,1 D. Segev,2 M. Schnitzler,3 H. Xiao,3 D. Axelrod,4 J. Tuttle-Newhall,3 D. Brennan,5 B. Kasiske,6 K. Lentine.3

    1Western Uni., London, Canada; 2John Hopkins Uni., Baltimore; 3Saint Louis Uni., St. Louis; 4Dartmouth Hitchcock Medical Center, Hanover; 5Washington Uni., St. Louis; 6Uni. of Minnesota, Minneapolis.

    Background: Currently, the demographic correlates and consequences of gout in living kidney donors are understudied.Methods: We examined a novel database that linked national U.S. identifiers…
  • 2015 American Transplant Congress

    Comparison of the Clinical Outcome and Surgical Invasiveness for Living Donor Nephrectomy Between Conventional Laparoscopic Surgery and Single-Port Surgery

    M. Saito, S. Satoh, R. Yamamoto, H. Tsuruta, S. Akihama, T. Inoue, S. Narita, N. Tsuchiya, T. Habuchi.

    Urology, Akita University Graduate School of Medicine, Akita, Japan.

    INTRODUCTION AND OBJECTIVES:Single-port surgery (SPS) for living donor nephrectomy (LDN) is challenging. Whether SPS is less invasive compared to conventional laparoscopic surgery (CLS) using several…
  • 2015 American Transplant Congress

    Extracorporeal Life Support: A Rescue Therapy in a Lung Transplantation Program

    P. Mohite, D. Gacia-Saez, B. Zych, N. Patil, M. Zeriouh, A. Koch, A.-F. Popov, A. Reed, M. Carby, F. DeRobertis, T. Bahrami, M. Amrani, S. Penn, S. Silver, S. Soresi, A. Simon.

    Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Harefield Hospital, Royal Brompton and Harefield NHS Foundation Trust, London, Middlesex, United Kingdom.

    Purpose: Extracorporeal Life Support (ECLS) is increasingly used as a bridge to lung transplantation (LTx) as well as in the management of severe primary graft…
  • 2015 American Transplant Congress

    Change in Physical Function Following Kidney Transplantation

    E. Lorenz, A. Cheville, B. Kotajarvi, F. Cosio, N. LeBrasseur.

    Mayo Clinic, Rochester, MN.

    Introduction: Improved physical function is associated with increased survival in the general population. Little is known about whether physical function improves following kidney transplant. The…
  • 2015 American Transplant Congress

    Differences in Reactivity of HLA-Specific Antibodies May Be Explained By Differences in Their Affinities for Selected Epitopes on HLA Proteins

    S. Daga,1,2 D. Lowe,6 R. Buchli,5 J. Collard,5 A. Mulder,8 C. McMurtrey,4,5 H. Moyse,7 N. Evans,7 N. Krishnan,2 W. Hildebrand,4,5 F. Claas,8 D. Briggs,3 D. Zehnder,1,2 D. Mitchell,1 R. Higgins.1,2

    1Clinical Sciences Research Laboratories, University of Warwick, Coventry, United Kingdom; 2Renal Unit, University Hospital, Coventry and Warwickshire NHS Trust, Coventry, United Kingdom; 3Department of Histocompatibility and Immunogenetics, NHS Blood and Transplant, Birmingham, United Kingdom; 4University of Oklahoma Health Science Center, Oklahoma City; 5Pure Protein LLC, Oklahoma City; 6Department of Histocompatibility and Immunogenetics, Royal Liverpool University Hospital, Liverpool, United Kingdom; 7School of Engineering, University of Warwick, Coventry, United Kingdom; 8Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.

    Affinity of IgG immunoglobulins for antigen varies and matures within the evolution of immune responses. Affinity is likely to be different for different epitope-antibody interactions…
  • 2015 American Transplant Congress

    Gene Expression of Kidney Biopsies Reveals Common Mechanisms of Rejection and a Cluster of Co-Expressed Genes Predictive of Long-term Outcomes

    B. Modena,1 S. Kurian,1 J. Friedewald,2 F. Harrison,1 T. Gelbart,1 S. Head,1 M. Abecassis,2 D. Salomon.1

    1The Scripps Research Institute, La Jolla; 2Northwestern University, Chicago.

    Purpose: Acute rejection (AR) still affects 8-14% of kidney transplants and rates of 10-year graft loss remain unchanged in part due to chronic rejection (CR).…
  • 2015 American Transplant Congress

    The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance

    D. Leonard, K. Shanmugarajah, H. Powell, A. Albritton, C. Mallard, D. Sachs, C. Cetrulo, Jr., J. Kurtz.

    Transplantation Biology Research Center, Massachusetts General Hospital, Boston, MA.

    Background: We have developed a reproducible model for induction of tolerance of all components of VCAs across haploidentical MHC barriers in miniature swine. The purpose…
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