ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Increased Risk of VRE Infection in Liver Transplant Patients With MELD of 35 or Greater

    A. Nelson,1 R. Girlanda.2

    1Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC; 2Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    Vancomycin Resistant Enterococcus (VRE) infection is recognized as a cause of morbidity in liver transplant patients. In the wake of Share 35, sick patients receiving…
  • 2015 American Transplant Congress

    Mesenchymal Stem Cells Suppress Cytotoxicity of Activated Natural Killer Cells in Liver Via the TRAIL-TRAIL Receptor Pathway in Islet Transplantation

    N. Ishida, K. Ishiyama, F. Hirata, Y. Saeki, Y. Tanaka, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Introduction: Innate immune reactions against islet grafts are considered a major obstacle for intraportal islet transplantation. We have previously reported that liver natural killer (NK)…
  • 2015 American Transplant Congress

    Phenotype Characterization, Migratory Pathways, Engraftment and Safety Evaluation of Human Cord Blood Derived Ex-Vivo Created Di- Chimeric Cells in NOD SCID Mouse Model: A Preliminary Study

    J. Cwykiel,1 A. Sklodowska,1 W. Malewski,1 M. Cyran,1 H. Karagoz,1 E. Bryndza Tfaily,1 M. Askar,2 M. Siemionow.1

    1Department of Orthopaedics, University of Illinois at Chicago, Chicago, IL; 2Transplant Center, Cleveland Clinic, Cleveland, OH.

    PURPOSE: The aim of this study was to evaluate safety, survival, migration and engraftment of ex-vivo fused human cord blood derived di-chimeric cells (DCC) in…
  • 2015 American Transplant Congress

    Renal Allografts Demonstrate Improved Pathology After Belatacept Therapy

    T. Saavedra,1 O. Opara,1 R. McLoughlin,1 B. Philosophe,2 C. Drachenberg,1 M. Weir,1 S. Bartlett,1 D. Leeser,1 J. Bromberg,1 R. Barth.1

    1University of Maryland School of Medicine, Baltimore; 2Johns Hopkins University, Baltimore.

    Belatacept provides immunosuppression via costimulation blockade and has been associated with improved renal function compared to calcineurin inhibitor based therapies. We developed the Maryland Aggregate…
  • 2015 American Transplant Congress

    Integrated Clinical-Histological (ICH) Score System for the Evaluation of “Marginal” Donors in Kidney Transplantation

    M. Fiorentino,1 M. Rossini,1 P. Gallo,1 G. Castellano,1 A. Schena,1 G. Grandaliano,2 P. Ditonno,3 M. Bataglia,3 L. Gesualdo.1

    1Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, Nephrology, Dialysis and Transplantation Unit, University of Foggia, Foggia, Italy; 3Department of Emergency and Organ Transplantation, Andrology, Urology and Renal Transplantation Unit, University of Bari, Bari, Italy.

    INTRODUCTION: The organ shortage has led to increase the procurement of kidney from “marginal” donors and to improve the strategies to better evaluate the quality…
  • 2015 American Transplant Congress

    Six-Month Urinary CCL2 Levels Predict Long-Term Renal Allograft Outcome

    J. Ho,1 D. Rush,1 A. Gao,1 H. Hopfer,2 C. Wiebe,1 P. Nickerson,1 S. Schaub,2 P. Hirt-Minkowski.2

    1Internal Medicine, Nephrology, University of Manitoba, Winnipeg, MB, Canada; 2Transplantation Immunology & Nephrology, University Hospital, Basel, Basel, Switzerland.

    Graft loss is a major cause of morbidity and mortality. We have shown that 6-month urine CCL2 is an independent predictor for death-censored graft loss.…
  • 2015 American Transplant Congress

    Elective Allograft Nephrectomy After Transplant Failure

    J. Augustine, K. Woodside, K. Noon, D. Hricik, E. Sanchez, J. Schulak.

    University Hospitals, Transplant Institute, Cleveland, OH.

    Background/Methods: Because of high rates of allograft intolerance and alloantibody sensitization after kidney transplant failure, we undertook a pilot study of elective allograft nephrectomy (ENx)…
  • 2015 American Transplant Congress

    Predicting Renal Recovery After Liver Transplant With Severe Pretransplant Sub-Acute Kidney Injury: The Impact of Warm Ischemic Time

    H. Laskey, T. Nydam, A. Wiseman, S. Biggins.

    Hepatology, Transplant Surgery and Nephrology, Univ. Colorado, Aurora, CO.

    Identification of which liver transplant candidates with severe kidney injury can have full recovery of renal function after liver only transplant is difficult. Avoiding unnecessary…
  • 2015 American Transplant Congress

    Live Donor Vs Deceased Donor Liver Transplantation Results in Identical Outcome in Recipients With Acute Liver Failure – An Important Choice for Critical Ill Patients

    N. Goldaracena, G. Sapisochin, J. Echeverri, M. Kaths, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, G. Levy, A. Ghanekar, E. Renner, D. Grant, M. Selzner.

    Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Introduction: Live donor liver transplantation (LDLT) is a valid alternative to deceased donor liver transplantation (DDLT) in patients suffering from acute liver failure (ALF). Rapid…
  • 2015 American Transplant Congress

    Quantifying Risk of ESRD in Live Kidney Donors

    A. Massie, A. Muzaale, X. Luo, D. Segev.

    Johns Hopkins, Baltimore.

    Among live kidney donors higher overall risk of ESRD has been shown in African-Americans and men. However, individual risk of ESRD has not been quantified.METHODS:…
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