2015 American Transplant Congress
The Gut Microbiota Regulates Murine Cardiac Transplant Outcome
1University of Maryland, Baltimore, MD; 2University of Hohenheim, Stuttgart, Germany.
Hypothesis: The gut microbiota regulates systemic immunity. Different characteristics of the microbiota can be defined that have pro- or anti-inflammatory effects. We tested the hypothesis…2015 American Transplant Congress
Assessment of IgG Subclass Significance for Early Graft Rejection and Long-Term Survival in HLA-Antibody Incompatible Renal Transplantation: Multivariate Approach
Donor HLA specific antibodies (DSA) can cause acute rejection and graft lost after renal transplantation. However neither the damaging antibody types, nor their acceptable levels…2015 American Transplant Congress
Epidemiology of Pneumonia in a Cohort of 5,000+ Abdominal Solid Organ Transplant Recipients
Baylor Scott & White Health, Dallas, TX.
Study purposeWe evaluated the epidemiology of pneumonia (PNE) in a longitudinal cohort of patients with abdominal (kidney, liver, and/or pancreas) solid organ transplants (SOT).MethodsRetrospective study…2015 American Transplant Congress
Impaired Autophagy: A Mechanism of Fatty Liver Increases Susceptibility to Ischemia Reperfusion Injury
BACKGROUND: Hepatic steatosis is associated with significant morbidity and mortality after transplantation. Autophagy was known as a protective response to ischemia and reperfusion (I/R) injury.…2015 American Transplant Congress
Human Leukocyte Antigen Mismatch and Steroid Maintenace in Kidney Transplantation
Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.
Kidney transplant recipients (KTRs) with zero/minimal HLA mismatches against their donors enjoy superior long term outcomes related to diminished immune response of the recipient against…2015 American Transplant Congress
Changes in Utilization, Discard, and Outcomes Associated With Hepatitis C (+) Donor Livers in the Era of Direct Acting Anti-Retroviral Therapy
Johns Hopkins University, Baltimore, MD.
While 45% of liver candidates are hepatitis C (HCV) (+) and might benefit from an HCV (+) donor liver, only 7.1% receive one, and HCV…2015 American Transplant Congress
Economic Analysis of Kidney Transplant Tolerance: The Holy Grail Is Less Costly
Transplant Surgery, Massachusetts General Hospital, Boston, MA.
Introduction: Kidney transplantation (KTx), although expensive, is a more cost effective treatment for end-stage renal disease (ESRD) than dialysis, and provides better long term survival…2015 American Transplant Congress
B Cell Depletion With an Anti-CD20 Antibody Enhances Alloreactive Memory T Cell Response After Transplantation
Pre-transplant B cell depletion in NHP with Rituximab (IgG1 anti-CD20 mAb) combined with cyclosporin A has been shown to promote the survival of islets allografts.…2015 American Transplant Congress
MELD Velocity – An Early Predictor of Increased Mortality Risk
INTRODUCTION: MELD is a satisfactory predictor of 3-month mortality in patients with cirrhosis. However, sub-populations of patients at increased hazard of mortality, but not well…2015 American Transplant Congress
Risk Stratification in Tailoring Induction Therapy in Kidney Transplant Recipients(KTR): Is It Cost-Effective?
Transplant, Univ. of Utah, Salt Lake City, UT.
Intro: Selecting induction therapy based on immunologic risk in KTR has gained popularity but there has yet to be a study evaluating the cost beyond…
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