- 2015 American Transplant Congress - Defining and Directing T Cell Subsets Involved in Rejection of Vascularized Composite Allografts- Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD. Purpose: Wider utilization of VCA is hampered by the need for long-term immunosuppression. Barriers to more targeted immunosuppression in VCA include (1) limited knowledge of…
- 2015 American Transplant Congress - Is Ex Vivo Liver Perfusion a Safe Alternative to Cold Static Storage for the Preservation of Standard Criteria Grafts?- Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada. Objective: Subnormothermic ex vivo liver perfusion (SNEVLP) has recently attracted great interest in the field of organ preservation for marginal grafts. However, data is lacking…
- 2015 American Transplant Congress - The 20S Proteasome Is Active in Apoptotic Nanovesicles and Controls Anti-LG3 Antibody ProductionHumoral autoreactivity to apoptotic cells and perlecan/LG3, a proteoglycan fragment released by apoptotic cells, predicts poor allograft outcomes in renal transplant patients. How apoptotic cells…
- 2015 American Transplant Congress - Pancreas Transplant Sera Improves the Function and Proliferation of Endothelial Cells- Transplant Services, Allegheny General Hospital, Pittsburgh, PA. Pancreas transplantation (Tx) allows for the study of diabetes by examining the reversal of the disease. Previously, we observed that after pancreas Tx many patients'…
- 2015 American Transplant Congress - High Kidney Donor Profile Index (KDPI) Correlates With Calculated Pulsatile Perfusion (PP) Resistance Index (RI) and Delayed Graft Function (DGF)- Surgery/Transplant, The Ohio State University Medical Center, Columbus, OH. Background: Deceased donor (DD) kidney quality is now being determined by calculating the Kidney Donor Profile Index (KDPI). Calculated kidney vascular resistance index (RI) during…
- 2015 American Transplant Congress - One Year Outcomes and Quality of Life Measurements in 127 Extended Criteria Donor Recipients- A Single Centre Comparative StudyIntroduction: Expanded criteria donors (ECDs) are those aged over 60 or 50-59 with 2 of: hypertension, death from cerebrovascular cause or terminal serum creatinine over…
- 2015 American Transplant Congress - Toxicity Driven Conversion to Belatacept in Kidney Transplant Recipients- Yale-New Haven Transplantation Center, New Haven, CT. Purpose: Evaluate the result of conversion to belatacept from calcineurin inhibitor (CNI) or TOR inhibitor based regimens due to toxicities in kidney transplant recipients (KTR).Methods:…
- 2015 American Transplant Congress - Infectious Complications in ABO Incompatible Kidney Transplantation Recipient According to the Rituximab DoseBackgroundDesensitization with rituximab and intravenous immunoglobulin improves ABO incompatible (ABOi) kidney transplantation (KT) outcomes. However, infections have been noted in association with rituximab administration. In…
- 2015 American Transplant Congress - Grip Strength, Gait Speed, and Chair Stands Predict Sarcopenia in Male But Not Female Liver Transplant Candidates- University of California, San Francisco, San Francisco, CA. Background: Sarcopenia, as determined by cross-sectional skeletal muscle index (SMI), is associated with waitlist mortality in liver transplant (LT) candidates, but has limited clinical utility…
- 2015 American Transplant Congress - Distal Splenorenal Shunt (DSRS): A Durable Bridge to Liver Transplantation- Transplantation and Hepatobiliary Diseases, Lahey Clinic Medical Center, Burlington, MA. Background: Variceal bleeding has a high rate of in-hospital mortality approaching 50%. Patients with well-compensated cirrhosis and recurrent variceal bleeding may benefit from long-term prophylaxis…
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