ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Operating Room Extubation After Bilateral Lung Transplantation in Cystic Fibrosis Patients: A Single Center Experience

    M.-L. Felten,1 J.-D. Moyer,1 J.-Y. Marandon,1 J.-F. Dreyfus,2 M. Fischler.1

    1Anesthesiology Department, Foch Hospital, Suresnes, Hauts-de-Seine, France; 2Research and Innovation Department, Foch Hospital, Suresnes, Hauts-de-Seine, France.

    Short-acting anesthetic drugs, thoracic epidural analgesia and a strict ventilation weaning protocol could permit extubation in the operating room (OR) (1). Aims of this study…
  • 2015 American Transplant Congress

    Re-Evaluate the Transplant Renal Artery Stenosis After Renal Transplantation Based On New Unenhanced Magnetic Resonance Angiography By Using Spatial Labeling With Multiple Inversion Pulses

    J. Wen,1 L. Zhang,2 Y. Li,2 X. Li,1 Z. Zhang,1 J. Chen,1 D. Cheng,1 Z. Liu.1

    1Jinling Hospital, Nanjing University School of Medicine, National Clinical Research Center of Kidney Diseases, Nanjing, China; 2Jinling Hospital, Nanjing University School of Medicine, Department of Radiology, Nanjing, China.

    Transplant renal artery stenosis (TRAS) after renal transplantation was underestimated because of the low sensitivity of ultrasound and the contrast induced renal damage on the…
  • 2015 American Transplant Congress

    Longitudinal Multi-Omic Profiling of Genes and Pathways Underlying Cardiac Allograft Rejection

    B. Piening,1 Y. Li,2 A. Shaked,2 B. Keating,2 M. Snyder.1

    1Genetics, Stanford University School of Medicine, Stanford, CA; 2University of Pennsylvania, Philadelphia, PA.

    Our ability to treat cardiac allograft rejection in both acute and chronic states is typically limited by poor existing biomarkers to predict the occurrence of…
  • 2015 American Transplant Congress

    Perturbation of Polyomavirus Nephropathy-Specific Gene Expression in Kidney Allografts

    T. Sigdel,1 O. Bestard,1,2 N. Salomonis,3 S.-C. Hsieh,1 M. Naesens,4 J. Torras,2 T. Tran,1 S. Roedder,1 M. Sarwal.1

    1Department of Transplant Surgery, UCSF, San Francisco, CA; 2Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, CAT, Spain; 3Cincinnati Childrens Hospital Medical Center, Cincinnati, OH; 4Nephrology Department, University Hospitals Leuven, Leuven, Belgium.

    Polyomavirus nephropathy (PVAN) is a common cause of kidney allograft dysfunction and loss. Microscopic observations of PVAN are similar to T-cell mediated rejection (TCMR), with…
  • 2015 American Transplant Congress

    Defining and Directing T Cell Subsets Involved in Rejection of Vascularized Composite Allografts

    M. Fryer, G. Furtmùller, B. Oh, S. Reddy, K. Sarhane, G. Raimondi, G. Brandacher, D. Cooney.

    Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.

    Purpose: Wider utilization of VCA is hampered by the need for long-term immunosuppression. Barriers to more targeted immunosuppression in VCA include (1) limited knowledge of…
  • 2015 American Transplant Congress

    Is Ex Vivo Liver Perfusion a Safe Alternative to Cold Static Storage for the Preservation of Standard Criteria Grafts?

    N. Goldaracena, V. Spetzler, M. Kaths, J. Echeverri, M. Selzner.

    Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Objective: Subnormothermic ex vivo liver perfusion (SNEVLP) has recently attracted great interest in the field of organ preservation for marginal grafts. However, data is lacking…
  • 2015 American Transplant Congress

    The 20S Proteasome Is Active in Apoptotic Nanovesicles and Controls Anti-LG3 Antibody Production

    M. Dieudé,1,4 C. Bell,2,4 J. Turgeon,1,4 D. Beillevaire,1,4 K. Hamelin,1,4 S. Qi,1,4 N. Pallet,1,4 C. Rondeau,3 D. Gingras,3 M. Desjardins,3 P. Thibault,2,4 M.-J. Hébert.1,4

    1Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada; 2Institute for Research in Immunology and Cancer (IRIC), Montreal, QC, Canada; 3Université de Montréal, Montreal, QC, Canada; 4Canadian National Transplant Research Program (CNTRP), Montreal, Canada.

    Humoral autoreactivity to apoptotic cells and perlecan/LG3, a proteoglycan fragment released by apoptotic cells, predicts poor allograft outcomes in renal transplant patients. How apoptotic cells…
  • 2015 American Transplant Congress

    Pancreas Transplant Sera Improves the Function and Proliferation of Endothelial Cells

    J. Pollett, L. Margetich, N. Thai.

    Transplant Services, Allegheny General Hospital, Pittsburgh, PA.

    Pancreas transplantation (Tx) allows for the study of diabetes by examining the reversal of the disease. Previously, we observed that after pancreas Tx many patients'…
  • 2015 American Transplant Congress

    High Kidney Donor Profile Index (KDPI) Correlates With Calculated Pulsatile Perfusion (PP) Resistance Index (RI) and Delayed Graft Function (DGF)

    R. Pelletier, M. Henry.

    Surgery/Transplant, The Ohio State University Medical Center, Columbus, OH.

    Background: Deceased donor (DD) kidney quality is now being determined by calculating the Kidney Donor Profile Index (KDPI). Calculated kidney vascular resistance index (RI) during…
  • 2015 American Transplant Congress

    One Year Outcomes and Quality of Life Measurements in 127 Extended Criteria Donor Recipients- A Single Centre Comparative Study

    Y. Tabbakh,1 S. Turner,1 H. Maple,1 C. Callaghan,1 J. Olsburgh,1 F. Calder,1 M. Drage,1 N. Karydis,1 I. Loukopoulos,1 G. Koffman,1 R. Hilton,1 J. Pattison,1 C. Farmer,3 S. Shah,2 E. Spigler,1 N. Mamode,1 N. Kessaris.1

    1Guys Hospital, London, United Kingdom; 2Kings Hospital, London, United Kingdom; 3Kent & Canterbury Hospital, Kent, United Kingdom.

    Introduction: Expanded criteria donors (ECDs) are those aged over 60 or 50-59 with 2 of: hypertension, death from cerebrovascular cause or terminal serum creatinine over…
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