Am J Transplant, Volume 5, Suppl 3 Archives - Page 130 of 170 - ATC Abstracts

2015 American Transplant Congress
Donor Specific Antibodies (DSA) Increase the Risk for Rejection After Pancreas Transplantation Qithout Negatively Impacting Survival
M. Marquez, M. Dib, G. Sapisochin, J. Laurence, A. Barbas, F. Bazerbachi, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattal.
Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.
Donor-specific antibodies (DSA) have been associated with increased rejection and lower kidney transplant survival. The impact of DSA on pancreas transplant outcomes in patients with…
2015 American Transplant Congress
TGFβ Production By B Cells Is Critical for Transplant Tolerance Induction
J. Kim,¹ W. Liu,^1,2 L. Liu,^1,2 K. Lee,¹ R. Stott,¹ H. Yeh,¹ J. Markmann.¹
¹Surgery, Massachusetts General Hospital / Harvard Medical School, Boston, MA; ²Surgery, Chengdu Military General Hospital, Chengdu, Sichuan, China.
Regulatory B cells (Bregs) have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined…
2015 American Transplant Congress
Process Deviation Tracking and Analysis in an Organ Procurement Organization
B. Schleich,¹ S. Yoon,¹ M. Khasawneh,¹ K. Srihari,¹ H. Irving,² A. Friedman.
¹Systems Science and Industrial Engineering, State University of New York at Binghamton, Binghamton, NY; ²New York Organ Donor Network, New York, NY.
"It is common practice for Organ Procurement Organizations (OPOs) to report, collect and track issues and problems occurring during the organ donation process. We labeled…
2015 American Transplant Congress
MicroRNA let-7i Targeting IL-10 Via JAK1-STAT3 Signal Pathway Regulates Dendritic Cells Maturation Subsequently Induces Cardiac Allograft Tolerance
J. Wu,^2,3 X. Jin,¹ Y. Sun,^2,3 X. Liu,^2,3 D. Chi,^2,3 B. Yu.^2,3
¹Thoracic Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China; ²Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; ³Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: Our previous study demonstrated that microRNA (MiR) let-7i could regulate dendritic cells (DCs) maturation and functional state via targeting SOCS1. In this study, we…
2015 American Transplant Congress
Development of a Targeted Genetic Renal Disease Panel With NexGen Sequencing for Unbiased Testing of Living Kidney Donors for Genetic Kidney Disease
C. Thomas,¹ Z. Stewart,³ A. Mansilla,² S. Mason,² A. Kwitek,² C. Campbell,² R. Smith,^1,2 R. Smith.^1,2
¹Internal Medicine, University of Iowa, Iowa City, IA; ²Institute of Human Genetics, University of Iowa, Iowa City, IA; ³Surgery, University of Iowa, Iowa City, IA.
Recent studies indicate that living donors biologically related to their transplant recipient may be at higher risk of ESRD compared to unrelated donors, possibly secondary…
2015 American Transplant Congress
The Extended Toronto Criteria for Transplantation for Hepatocellular Carcinoma. A Validation Study
G. Sapisochin, N. Goldaracena, J. Laurence, M. Dib, A. Barbas, A. Ghanekar, L. Lilly, E. Renner, M. Selzner, M. Cattral, I. McGilvray, D. Grant, P. Greig.
Multi-Organ Transplant, Toronto General Hospital. University of Toronto, Toronto, ON, Canada.
Liver transplant (LT) listing criteria for patients with hepatocellular cancers (HCC) that exceed the Milan criteria are still controversial. At the University of Toronto, we…
2015 American Transplant Congress
BAFF Binding to T Cell-Expressed BAFF-R Promotes Follicular Helper T Cell Proliferation and GC B Cell Responses
M. Chen,¹ Q. Li,¹ W. Stohl,² S. Zheng,² X. He,¹ Z. Guo.¹
¹Organ Transplant Center, 1st affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; ²Division of Rheumatology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.
Recent studies have defined a crucial role for the B cell–activating factor belonging to TNF family (BAFF) in promoting germinal center (GC) responses in mouse…
2015 American Transplant Congress
Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance
B. Weist,^1,2 M. Schmueck,² M. Dziubianau,² P. Reinke,^1,2 N. Babel.^1,2
¹Department of Nephrology, Charite Universitaetsmedizin, Berlin, Germany; ²BCRT, Charite Universitaetsmedizin, Berlin, Germany.
Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…
2015 American Transplant Congress
Utility of Anti-Phospholipase A2 Receptor (Anti-PLA2R) ELISA Testing in Predicting Post-Transplant Idiopathic Membranous Nephropathy (IMN)
C. VanBeek,¹ D. Thomas,² A. Jimenez,² A. Vo,² S. Jordan,² M. Toyoda.²
¹Pathology, Cedars-Sinai Medical Center, Los Angeles, CA; ²Transplant Immunology, Cedars-Sinai Medical Center, Los Angeles, CA.
Backgound: IMN is frequently associated with autoantibodies to the podocyte antigen, PLA2R. Anti-PLA2R associated IMN is diagnosed by detecting PLA2R antigen within glomerular immune complexes…
2015 American Transplant Congress
Combined Robotic Kidney Transplantation and Sleeve Gastrectomy in Obese Recipients: Initial Results from Prospective Randomized Study
I. Tzvetanov, G. D'Amico, G. Georgiev, H. Jeon, R. Garcia-Roca, E. Benedetti, J. Oberholzer.
Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.
IntroductionIn many transplant centers, patients with a BMI above 40 kg/m2 are either completely excluded or required to lose weight before being considered for kidney…