ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    High Mortality in Diabetic Recipients of High KDPI Deceased Donor Kidneys

    R. Pelletier,1 T. Pesavento,2 A. Rajab,1 M. Henry.1

    1Surgery/Transplant, The Ohio State University Medical Center, Columbus, OH; 2Transplant Nephrology, The Ohio State University Medical Center, Columbus, OH.

    Deceased donor (DD) kidney quality is determined using the Kidney Donor Profile Index (KDPI). How best to allocate the high KDPI kidneys (KDPI ≥ 85%)…
  • 2015 American Transplant Congress

    A Comparison of Alemtuzumab and Antithymocyte Globulin Induction in High-Risk, Non-Sensitized African American Renal Transplant Recipients

    M. Janusek,1 S. Patel,2 K. Galen,1 P. West-Thilke,1 E. Benedetti,1 J. Thielke.1

    1University of Illinois Hospital and Health Sciences System, Chicago, IL; 2VA Great Lakes Health Care System, Westchester, IL.

    Background:Greater than 90% of all kidney transplants(KTx) today receive an induction agent. The choice of a depleting or non-depleting agent is center specific. Alemtuzumab (Alem),…
  • 2015 American Transplant Congress

    The Role of Immunosuppression on Cardiac Functions of Kidney Transplant Recipients

    U. Cakir, O. Cavdaroglu, T. Erturk, E. Gurluler, A. Gurkan, I. Berber.

    Transplant Center, Acibadem University, Istanbul, Turkey.

    Cardiac disorders are associated with high morbidity and mortality in end-stage renal disease (ESRD).Kidney transplantation is known to increase the survival of dialysis patients by…
  • 2015 American Transplant Congress

    HCV Treatment in Liver Transplantation: Changes in Center Attitudes and Practices in the DAA Era

    A. Shaffer, A. Cash, S. Anjum, D. Segev, C. Durand.

    Surgery, Johns Hopkins University, Baltimore, MD.

    Chronic hepatitis C virus infection (HCV) is the leading indication for liver transplantation (LT) in the US. Safe and effective directly acting antivirals (DAAs) are…
  • 2015 American Transplant Congress

    Hepatic T Cells Derived from Normothemic Machine Perfused Grafts Contained More Regulatory T Cells and Fewer Proinflammatory Cytokines Producing T Cells Than Those from Cold Storage Grafts

    X. Huang, R. Ravikumar, C. Coussios, P. Srinivasan, N. Heaton, P. Friend, W. Jassem, Y. Ma.

    1Institute of Liver Studies, King's College London School of Medicine at King's College, London, United Kingdom; Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom.

    Background & aim:In liver transplantation, ischemia reperfusion (I/R) injury is associated with an inflammatory response affecting graft and patient outcomes. Ex-vivo normothermic machine perfusion (NMP)…
  • 2015 American Transplant Congress

    Assessment of Actual Pediatric Organ Donation Potential: Neurologic and Circulatory Determination of Death at a Children's Hospital

    C. Aguayo,1 E. Bennett,2 J. Sweney,2 C. Myrick,1 S. Bratton.2

    1Intermountain Donor Services, Salt Lake City, UT; 2Pediatrics, University of Utah, Salt Lake City, UT.

    BACKGROUND AND OBJECTIVES: Organ donation after circulatory determination of death (DCDD) is increasing. DCDD offers potential for additional abdominal organ donation. We evaluated all dying…
  • 2015 American Transplant Congress

    Attitudes and Beliefs About Organ Donation: Focus Group Study in Arabic-Speaking Communities in Australia

    A. Ralph,1,2 A. Alyami,3,4 R. Allen,3,4 K. Howard,1 J. Craig,1,2 S. Chadban,3,4 M. Irving,1,2 A. Tong.1,2

    1Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; 2Centre for Kidney Research, Children's Hospital at Westmead, Westmead, NSW, Australia; 3Sydney Medical School, University of Sydney, Sydney, NSW, Australia; 4Transplantation Services, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

    Background: The demand for transplantable organs continues to outweigh supply across the globe, especially in the provision of deceased donor organs from ethnic minority populations.…
  • 2015 American Transplant Congress

    Human Adipose Derived Mesenchymal Stem Cells Enhance Bone Marrow Engraftment and Induce Immunological Tolerance

    R. Saidi,2 B. Rajeshkumar,1 P. Agrawal,1 M. Rashighi.1

    1UMASS, Worcester; 2Alpert Medical School of Brown University, Providence.

    Organ transplantation currently requires long-term immunosuppression. This is associated with multiple complications including infection, malignancy and other toxicities. Immunologic tolerance is considered the optimal solution…
  • 2015 American Transplant Congress

    Relative In Vitro Immunoregulatory Effects of Everolimus, Sirolimus, Tacrolimus, Mycophenolic Acid and Drug Combinations

    J. Mathew, X. Huang, J. Leventhal, L. Gallon, J. Miller, J. Levitsky.

    Surgery - Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Everolimus (EVL) is a modified form of the mTOR-inhibitor Sirolimus (SRL) and is used clinically in combination with Mycophenolate (MMF) and/or Tacrolimus (TAC). The purpose…
  • 2015 American Transplant Congress

    Chimerism for Early Detection of Graft Versus Host Disease in Intestinal Transplantation

    J. Garcia, T. Beduschi, P. Ruiz, A. Tekin, J. Fan, S. Nishida, G. Selvaggi, L. Cubley, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Graft versus host disease (GVHD) is a potentially fatal complication after multivisceral transplantation (MVT). By definition, donor cells must be present in the blood of…
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