2015 American Transplant Congress
Prehypertension and Abnormal Fasting Glucose Are the Main Factors Associated With Progressive Deterioration of Renal Function in Kidney Donors
Background: For reasons unclarified, some kidney donors (KD) are patients (pts) that throughout its evolution remain with the same renal function (RF) or even continue…2015 American Transplant Congress
Living Kidney Donation in the Elderly: The United Kingdom Experience
Introduction: The increasing demand for organs has led many institutions to accept elderly patients onto their living donor programmes. However no large UK based datasets…2015 American Transplant Congress
Induction Avoidance in 2-Haplotype-Matched White Living Kidney Transplantation
Background: We hypothesize that 2-haplotype matched white living kidney transplant recipients carry a low immunologic risk for rejection, and therefore do not give induction therapy…2015 American Transplant Congress
The Preservation Technique Modulates the Immunological Milieu in Lung Transplantation and Affects the Pro-/ Anti-Inflammatory Balance
Little is known regarding the influence of different preservation techniques (i.e. cold static storage with Perfadex® or Celsior® solution) on the immunological milieu, especially lung-resident…2015 American Transplant Congress
Change in Frailty Status Over Time Among In-Center Hemodialysis ESRD Patients in the ACTIVE/ ADIPOSE Study
Emory University, Atlanta, GA.
Introduction: Frailty among End Stage Renal Disease (ESRD) is associated with poor health outcomes, including delayed graft function and hospitalization following transplantation. Although frailty is…2015 American Transplant Congress
Highly Accurate High-Resolution HLA Imputation Using Dense Genotyping Data
HLA similarity between donors (D) and recipients (R) of solid organ transplantation (SOT) plays a central role in determining the risk of rejection or graft-versus-host…2015 American Transplant Congress
Differentially Expressed Genes in Immunosuppressed Kidney Transplant Recipients
Introduction: In our effort to personalize immunosuppressive therapies we performed RNA sequencing (RNAseq) to identify differentially expressed genes (DEGs) after kidney transplant (tx) and the…2015 American Transplant Congress
Mesenchymal Stem Cell Therapy to Improve Functional Outcome in Vascular Composite Allotransplantation (VCA)
Madigan Army Medical Center, Tacoma.
Introduction: Although over 200 VCA including hand and face transplants have been performed worldwide with encouraging graft survival outcomes, long-term success with motor and sensory…2015 American Transplant Congress
Cardiac Xenotransplantation: Reconstituted B Cells After Rituxan Treatment Maintain Their Repertoire But Have a Muted Response to Xenoantigens
1CSRP/NIH/NHLBI, NIH, Bethesda, MD; 2DVR/ORS, NIH, Bethesda, MD; 3Revivicor Inc, Blacksburg, VA.
Background: Xentoranplantation (XTx) remains an option for end stage organ failure. Recently we have reported cardiac xenograft survival of over one year pig to baboon…2015 American Transplant Congress
Host NK Cell Allorecognition of Passenger Donor Lymphocytes Within Allografts Is Essential for Preventing Augmentation of Recipient Adaptive Alloimmunity
Department of Surgery, University of Cambridge, Cambridge, United Kingdom.
Background:Memory T cells are now appreciated to reside in peripheral non-lymphoid tissue, but how their presence within solid organ allografts impacts upon transplant outcomes is…
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