ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Differential Intragraft Gene Expression Profiles in Patients With Sterile Leukocyturia

    M. Ajaimy,1 P. O Broin,2 Y. Bao,1 J. Lindower,1 A. Golden,2 E. Akalin.1

    1Transplantation, Einstein/Montefiore Transplant Center, Bronx; 2Computational Genomics Facility, Albert/Einstein College of Medicine, Bronx.

    Objective: We aimed to investigate if sterile leukocyturia reflects increased intragraft immune activity and gene expression profiles of transplant kidney biopsies differ from patients without…
  • 2015 American Transplant Congress

    Speed of Onset of Donor Brain Death Leads to Differences in Renal Function and Expression of Inflammatory and Oxidative Stress Markers in Rat Kidneys

    D. Hoeksma,1 R. Rebolledo,2 M. Hottenrott,3 Y. Bodar,1 H. Leuvenink.1

    1Abdominal Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Faculty of Medicine, University of Chile, Santiago, Chile; 3Cardiothoracic Surgery, University Medical Center Groningen, Groningen, Netherlands.

    IntroductionDonor brain death (BD) is an independent risk factor for primary and delayed renal graft function. Furthermore, the speed of onset of brain death, traumatic…
  • 2015 American Transplant Congress

    Incidence, Risk Factors, and Outcomes of Hospitalized Urinary Tract Infections in Kidney Transplant Recipients

    H. Pang, C. Liang, O. Famure, Y. Li, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Background: Urinary tract infections (UTIs) are common complications in kidney transplant recipients (KTRs) due to their immunocompromised state. Severe infections often lead to hospitalizations and…
  • 2015 American Transplant Congress

    Immune Response to Kidney and Pancreas Self-Antigens Are Associated With Antibody Mediated Rejection in Simultaneous Kidney Pancreas Transplants

    M. Gunasekaran,1 A. Siddiq,2 S. Shenoy,1 J. Wellen,1 T. Mohanakumar.1

    1Surgery, Washington Univ Sch of Med, St. Louis, MO; 2Medicine, Washington Univ Sch of Med, St. Louis, MO.

    Background: Simultaneous kidney-pancreas transplantation (SKP Tx) is performed as treatment option for type-1 diabetes with end stage kidney diseases. Though allograft survival was improved with…
  • 2015 American Transplant Congress

    Isotype Switching of Antibodies to Vimentin Following Transplantation Is Associated With Development of Transplant Glomerulopathy Following Renal Transplantation

    M. Gunasekaran,1 T. Maw,3 R. Santos,3 J. Wellen,1 S. Shenoy,1 T. Mohanakumar.1,2

    1Surgery, Washington Univ Sch of Med, St. Louis, MO; 2Pathology & Immunology, Washington Univ Sch of Med, St. Louis, MO; 3Medicine, Washington Univ Sch of Med, St. Louis, MO.

    Background: Immune responses to tissue restricted self antigens have been proposed to play a role in transplant glomerulopathy (TG). The goal of this study is…
  • 2015 American Transplant Congress

    Bortezomib Treatment in Antibody Mediated Rejection After Kidney Transplantation

    J. Lee,1 J. Lee,1 B. Kim,2 Y. Park,3 M. Ju,1 M. Kim,1 S. Kim,1 Y. Kim,1 K. Huh.1

    1Department of Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Department of Internal Medicine, Yonsei University Health System, Seoul, Republic of Korea; 3Department of Laboratory Medicine, Yonsei University Health System, Seoul, Republic of Korea.

    BackgroundSeveral studies demonstrated bortezomib therapy for antibody-mediated rejection (AMR) in renal transplants. However, the treatment efficacy according to target antigen or occurrence time of AMR…
  • 2015 American Transplant Congress

    Outcomes After Listing for Kidney Transplantation in Adults Aged 70 Or Over

    D. Kanigicherla, I. Zia, M. Morton, S. Skampardoni, M. Picton.

    Renal Unit, Manchester Royal Infirmary, Manchester, Cheshire, United Kingdom.

    Background:Low likelihood of listing and subsequent deceased donor transplantation has previously been reported for the elderly with additional concerns about patient frailty, morbidity and mortality…
  • 2015 American Transplant Congress

    IL-17 Production Influenced by Induction Therapy With ATG

    D. Abendroth,1 M. Marzinzig,1 J. Kaden.2

    1Center of Surgery, University of Ulm, Ulm, Germany; 2Renal Transplant Center, Municipal Friedrichshain Hospital, Berlin, Germany.

    Introduction Immune-mediated rejection remains the most important cause of graft failure. Recently, a newly identified CD4+ T cell subset, Th17, distinct from Th1 or Th2,…
  • 2015 American Transplant Congress

    Progression of Coronary Artery Disease in High-Risk Patients Undergoing Renal Transplantation

    R. Corbett, N. Kumar, C. Baker, D. Moutzouris, M. Willicombe, J. Galliford, A. McLean, N. Duncan, D. Taube.

    Imperial College Renal and Transplant Centre, London, United Kingdom.

    Asymptomatic coronary artery disease [CAD] is common in patients with end-stage renal disease [ESRD]. While coronary revascularization prior to transplantation is associated with improved patient…
  • 2015 American Transplant Congress

    Exercise Therapy Improves Body Composition Change After Kidney Transplantation

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Long-term graft and patient survival after kidney transplant is affected by metabolic disorders such as hypertension, obesity and diabetes. The aim of this study…
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