ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Outcomes After Listing for Kidney Transplantation in Adults Aged 70 Or Over

    D. Kanigicherla, I. Zia, M. Morton, S. Skampardoni, M. Picton.

    Renal Unit, Manchester Royal Infirmary, Manchester, Cheshire, United Kingdom.

    Background:Low likelihood of listing and subsequent deceased donor transplantation has previously been reported for the elderly with additional concerns about patient frailty, morbidity and mortality…
  • 2015 American Transplant Congress

    IL-17 Production Influenced by Induction Therapy With ATG

    D. Abendroth,1 M. Marzinzig,1 J. Kaden.2

    1Center of Surgery, University of Ulm, Ulm, Germany; 2Renal Transplant Center, Municipal Friedrichshain Hospital, Berlin, Germany.

    Introduction Immune-mediated rejection remains the most important cause of graft failure. Recently, a newly identified CD4+ T cell subset, Th17, distinct from Th1 or Th2,…
  • 2015 American Transplant Congress

    Progression of Coronary Artery Disease in High-Risk Patients Undergoing Renal Transplantation

    R. Corbett, N. Kumar, C. Baker, D. Moutzouris, M. Willicombe, J. Galliford, A. McLean, N. Duncan, D. Taube.

    Imperial College Renal and Transplant Centre, London, United Kingdom.

    Asymptomatic coronary artery disease [CAD] is common in patients with end-stage renal disease [ESRD]. While coronary revascularization prior to transplantation is associated with improved patient…
  • 2015 American Transplant Congress

    Exercise Therapy Improves Body Composition Change After Kidney Transplantation

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Long-term graft and patient survival after kidney transplant is affected by metabolic disorders such as hypertension, obesity and diabetes. The aim of this study…
  • 2015 American Transplant Congress

    Incidence and Impact of De Novo Donor-Specific Anti-HLA Antibodies in ABO-Compatible Liver-Transplant Recipients

    A. Del Bello,1,2 N. Congy-Jolivet,2,3,4 D. Milongo,1 C. Guilbeau-Frugier,2,5 L. Lavayssière,1 F. Muscari,2,6 L. Rostaing,1,2,7 N. Kamar.1,2,7

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Université Paul Sabatier, Faculté de Médecine, Toulouse, France; 3Molecular Immunogenetics Laboratory, EA 3034, Faculté de Médecine Purpan, IFR150, Toulouse, France; 4Department of Immunology, CHU Rangueil, Toulouse, France; 5Department of Pathology, CHU Rangueil, Toulouse, France; 6Surgery and Liver Transplantation, CHU Rangueil, Toulouse, France; 7INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France.

    Background: The incidence and consequences of de novo donor-specific anti-HLA antibodies (DSAs) after liver transplantation (LT) are not well known. Thus, we investigated the incidence,…
  • 2015 American Transplant Congress

    Early Vs. Late Acute Antibody Mediated Rejection Among Renal Transplant Recipients in Terms of Its Response to Rituximab Therapy-Single Center Expereince

    N. Nampoory, T. Alotaibi, O. Gheith, M. Halim, T. Mahmoud, P. Nair, M. Abdulmoneim, S. Alwaheb, R. Hasan.

    Nephrology, OTC of Kuwait, kuwait, Kuwait.

    IntroductionThere are no comparable trials concerning the use of rituximab among renal transplant recipients with acute antibody mediated rejection.Aim of the study:We aimed to compare…
  • 2015 American Transplant Congress

    Utilization and Characteristics of Pancreas and Simultaneous Kidney-Pancreas Donors in the US by OPTN-Defined Increased Risk Donor Status

    M. Ison,1,2 B. Ho,2 J. Leventhal,2 D. Ladner.2

    1Infectious Diseases, Northwestern University, Chicago; 2Organ Transplantation, Northwestern University, Chicago.

    Background: The number of candidates in need of pancreas transplantation is far larger than the number of organ donors. To expand the organ pool, there…
  • 2015 American Transplant Congress

    Heart En Bloc Thymus Transplantation Permits Long-Term, Acute Rejection-Free Cardiac Allograft Survival in Nonhuman Primates (NHPs)

    M. Tonsho,1 P. Spencer,1 T. Millington,1 A. Muniappan,1 A. Tena,2 R. Smith,3 R. Colvin,3 J. Allan,1,2 J. Madsen.1,2,4

    1MGH Transplant Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA; 2Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA; 3Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; 4Cardiac Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

    BACKGROUNDThe role of vascularized thymus on tolerance induction has been well studied in swine recipients of kidney allografts, but not in NHP recipients of heart…
  • 2015 American Transplant Congress

    Altered Intestinal Microbiome as a Potential Biomarker for Failed Immune-Regulation in Autoimmune Type 1 Diabetes Mellitus

    P. Chhabra,1 A. Spano,2 D. Bowers,1 M. Wu,2 L. Langman,1 M. Timko,2 K. Brayman.1

    1Department of Surgery, University of Virginia, Charlottesville, VA; 2Department of Biology, University of Virginia, Charlottesville, VA.

    Purpose: Beta-cell destruction results due to a failure of immune-regulation in type 1 diabetes (T1D). We investigated alterations in the intestinal microbiome composition as a…
  • 2015 American Transplant Congress

    The Effect of Compatibility of ABO Blood Type Antigens on Graft Survival of Intestinal Transplants

    J. Cai,1 A. Qing,2 G. Wu,3 M. Everly,1 P. Terasaki.1

    1Terasaki Foundation Lab, Los Angeles; 2Lincoln High School, Stockton; 3The 4th Military Medical University, Xi-An, China.

    Due to the introduction of new immunosuppressive agents and development of pre- and post-transplant patient management, ABO blood group incompatibility is no longer considered an…
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