ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Assessment of Actual Pediatric Organ Donation Potential: Neurologic and Circulatory Determination of Death at a Children's Hospital

    C. Aguayo,1 E. Bennett,2 J. Sweney,2 C. Myrick,1 S. Bratton.2

    1Intermountain Donor Services, Salt Lake City, UT; 2Pediatrics, University of Utah, Salt Lake City, UT.

    BACKGROUND AND OBJECTIVES: Organ donation after circulatory determination of death (DCDD) is increasing. DCDD offers potential for additional abdominal organ donation. We evaluated all dying…
  • 2015 American Transplant Congress

    Attitudes and Beliefs About Organ Donation: Focus Group Study in Arabic-Speaking Communities in Australia

    A. Ralph,1,2 A. Alyami,3,4 R. Allen,3,4 K. Howard,1 J. Craig,1,2 S. Chadban,3,4 M. Irving,1,2 A. Tong.1,2

    1Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; 2Centre for Kidney Research, Children's Hospital at Westmead, Westmead, NSW, Australia; 3Sydney Medical School, University of Sydney, Sydney, NSW, Australia; 4Transplantation Services, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

    Background: The demand for transplantable organs continues to outweigh supply across the globe, especially in the provision of deceased donor organs from ethnic minority populations.…
  • 2015 American Transplant Congress

    Human Adipose Derived Mesenchymal Stem Cells Enhance Bone Marrow Engraftment and Induce Immunological Tolerance

    R. Saidi,2 B. Rajeshkumar,1 P. Agrawal,1 M. Rashighi.1

    1UMASS, Worcester; 2Alpert Medical School of Brown University, Providence.

    Organ transplantation currently requires long-term immunosuppression. This is associated with multiple complications including infection, malignancy and other toxicities. Immunologic tolerance is considered the optimal solution…
  • 2015 American Transplant Congress

    Relative In Vitro Immunoregulatory Effects of Everolimus, Sirolimus, Tacrolimus, Mycophenolic Acid and Drug Combinations

    J. Mathew, X. Huang, J. Leventhal, L. Gallon, J. Miller, J. Levitsky.

    Surgery - Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Everolimus (EVL) is a modified form of the mTOR-inhibitor Sirolimus (SRL) and is used clinically in combination with Mycophenolate (MMF) and/or Tacrolimus (TAC). The purpose…
  • 2015 American Transplant Congress

    Chimerism for Early Detection of Graft Versus Host Disease in Intestinal Transplantation

    J. Garcia, T. Beduschi, P. Ruiz, A. Tekin, J. Fan, S. Nishida, G. Selvaggi, L. Cubley, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Graft versus host disease (GVHD) is a potentially fatal complication after multivisceral transplantation (MVT). By definition, donor cells must be present in the blood of…
  • 2015 American Transplant Congress

    Acute Kidney Injury and Outcome After Cardiac Transplantation

    G. Fortrie,1 O. Manintveld,2 K. Caliskan,2 M. Betjes.1

    1Internal Medicine, Div. of Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; 2Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.

    Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…
  • 2015 American Transplant Congress

    Epidemiology and Outcomes of Pre-Transplant Methicillin Resistant Staphylococcus Aureus Screening in Pediatric Solid Organ Transplant Candidates

    G. Paulsen, S. Blum, L. Danziger-Isakov.

    Dept of Pediatrics/Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    Purpose: Infection following pediatric solid organ transplantation (SOT) is a major cause of morbidity and mortality. Peri-operative antibiotic prophylaxis is commonly used to reduce the…
  • 2015 American Transplant Congress

    Hypothermic Machine Perfusion Improves the Quality of Marginal Donor Pancreata

    M. Leemkuil,1 M. Engelse,2 R. Ploeg,3 E. de Koning,2 C. Krikke,1 H. Leuvenink.1

    1Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Nephrology, Leiden University Medical Center, Leiden, Netherlands; 3Transplant Biology, Oxford Transplant Center, Oxford, United Kingdom.

    Introduction. Pancreas or islet transplantation is considered the most effective treatment for patients with type 1 diabetes mellitus. Due to the persistent organ shortage, pancreata…
  • 2015 American Transplant Congress

    Third Party Mesenchymal Stromal Cell Infusion in Kidney Transplant Recipient: 6-Month Safety Interim Analysis

    L. Weekers,1 P. Erpicum,1 O. Detry,3 C. Lechanteur,2 E. Baudoux,2 F. Jouret,1 Y. Beguin.2

    1Nephrology, University Hospital of Liege, Liege, Belgium; 2Hematology, University Hospital of Liege, Liege, Belgium; 3Abdominal Surgery, University Hospital of Liege, Liege, Belgium.

    Back-groundMesenchymal stromal cell (MSC) have immunomodulating properties and could be used as immunosuppressive agents.We report the 6-month safety results for the 5 first patients treated…
  • 2015 American Transplant Congress

    Impacts of Mycophenolate Mofetile Addition to Very Low Exposure Everolimus and Calcineurine Inhibitor Based Immunosuppression in De Novo Kidney Transplantation

    Y. Watarai,1 M. Okada,1 K. Futamura,1 K. Ito,1 T. Yamamoto,1 M. Tsujita,1 T. Hiramitsu,1 N. Goto,1 S. Narumi,1 T. Kobayashi.2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; 2Applied Immunity, Nagoya University Graduate School of Medicine, Nagoya, Japan.

    Purpose: Prospective randomized study of MMF addition to everolimus (EVR) based immunosuppression was evaluated in clinical outcomes as well as protocol biopsies findings and donor…
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