2015 American Transplant Congress
Adherence Time-Profiles of Renal Transplant Patients During the Three First Years Post-Transplantation
Non-adherence to immunosuppressants (IS) has been reported to increase morbidity and mortality of transplant patients.Our objective was to investigate adherence to IS in renal transplant…2015 American Transplant Congress
ASKP1240 in De Novo Kidney Transplant Recipients
Primary objective was to evaluate the efficacy and safety of ASKP1240, antagonistic anti-CD40 antibody, in either a CNI free regimen or a CNI minimization regimen…2015 American Transplant Congress
Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection
Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…2015 American Transplant Congress
Plasmapheresis – A Previously Unrecognised Risk Factor for BK Viraemia
BK nephropathy is an important preventable cause of graft loss, with the only universally accepted risk factor being overall burden of immunosuppression. In the absence…2015 American Transplant Congress
Differential Intragraft Gene Expression Profiles in Patients With Sterile Leukocyturia
Objective: We aimed to investigate if sterile leukocyturia reflects increased intragraft immune activity and gene expression profiles of transplant kidney biopsies differ from patients without…2015 American Transplant Congress
Speed of Onset of Donor Brain Death Leads to Differences in Renal Function and Expression of Inflammatory and Oxidative Stress Markers in Rat Kidneys
IntroductionDonor brain death (BD) is an independent risk factor for primary and delayed renal graft function. Furthermore, the speed of onset of brain death, traumatic…2015 American Transplant Congress
Incidence, Risk Factors, and Outcomes of Hospitalized Urinary Tract Infections in Kidney Transplant Recipients
Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Background: Urinary tract infections (UTIs) are common complications in kidney transplant recipients (KTRs) due to their immunocompromised state. Severe infections often lead to hospitalizations and…2015 American Transplant Congress
Immune Response to Kidney and Pancreas Self-Antigens Are Associated With Antibody Mediated Rejection in Simultaneous Kidney Pancreas Transplants
Background: Simultaneous kidney-pancreas transplantation (SKP Tx) is performed as treatment option for type-1 diabetes with end stage kidney diseases. Though allograft survival was improved with…2015 American Transplant Congress
Isotype Switching of Antibodies to Vimentin Following Transplantation Is Associated With Development of Transplant Glomerulopathy Following Renal Transplantation
Background: Immune responses to tissue restricted self antigens have been proposed to play a role in transplant glomerulopathy (TG). The goal of this study is…2015 American Transplant Congress
Bortezomib Treatment in Antibody Mediated Rejection After Kidney Transplantation
BackgroundSeveral studies demonstrated bortezomib therapy for antibody-mediated rejection (AMR) in renal transplants. However, the treatment efficacy according to target antigen or occurrence time of AMR…
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