ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Transversal Observational Study On Recurrent and Late Urinary Tract Infections (UTIs) in Renal Transplantation (tx)

    G. Castellano,1 M. Fiorentino,1 M. Martino,1 M. Rossini,1 A. Schena,1 C. Manno,1 G. Grandaliano,2 P. Ditonno,3 M. Battaglia,3 L. Gesualdo.1

    1DETO, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, Nephrology, Dialysis and Transplantation Unit, University of Foggia, Foggia, Italy; 3DETO, Andrology, Urology and Renal Transplantation Unit, University of Bari, Bari, Italy.

    UTIs are common complications after kidney tx. The aim of this study was to define the potential predisposing factors and the possible impact on graf…
  • 2015 American Transplant Congress

    Outcomes Following Kidney Transplant With Low Level Positive Flow Cytometric Crossmatch

    C. Schinstock, F. Cosio, M. Gandhi, L. Cornell, M. Stegall.

    Mayo Clinic, Rochester, MN.

    Introduction: Highly-sensitized kidney transplant (KTx) candidates have difficulty finding a negative crossmatch donor. KTx with low level positive crossmatch might be the next best option.…
  • 2015 American Transplant Congress

    Antibodies Directed Against HLA-DQ Are Significantly Associated to Complement Activation In Vitro

    J. Arreola-Guerra, A. de Santiago, A. Arvizu, N. Gonzalez-Tableros, M. Lopez, M. Vilatoba, L. Morales-Buenrostro, J. Alberu, N. Castelan.

    1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Background: C1q-binding HLA antibodies (HLAabs) have been related to acute rejection and long-term graft loss. The characteristics of these antibodies and factors associated to complement…
  • 2015 American Transplant Congress

    Mycophenolic Acid Area-Under-Curve (MPA AUC) Levels Sufficient to Prevent Donor-Specific Antibody (DSA) Formation Are Not Associated With Higher Rates of CMV/EBV/BK Viral Infections

    S. Narins, D. Ladie, R. Saylor, E. Richards, H. Yang, M. Waybill.

    PinnacleHealth, Harrisburg, PA.

    Background: Prevention of DSA formation and antibody-mediated rejection mandates therapeutic doses of immunosuppressive agents, including MPA. We have shown that MPA AUC monitoring and dose…
  • 2015 American Transplant Congress

    Body Mass Index (BMI) Mismatch in Deceased Kidney Donation Is an Independent Risk Factor for Graft Failure

    O. Staeck,1 D. Khadzhynov,1 M. Mahn,2 K. Budde,1 F. Fuller,2 F. Halleck.1

    1Nephrology, Charite Universitaetsmedizin, Berlin, Germany; 2Urology, Charite Universitaetsmedizin, Berlin, Germany.

    IntroductionThe influence of this BMI-mismatch in deceased kidney donors and their recipients on graft survival is so far not well characterized.MethodsRetrospective long-term observational study of…
  • 2015 American Transplant Congress

    Molecular Features of Kidney Transplant Biopsies Without Allograft Injury in Relation With Type of Induction Therapy

    M. Ajaimy,1 P. O Broin,2 M. Lubetzky,1 Y. Bao,1 A. Golden,2 E. Akalin.1

    1Transplantation, Einstein/Montefiore Transplant Center, Bronx; 2Computational Genomics Facility, Albert/Einstein College of Medicine, Bronx.

    Objective: Molecular evidence of allograft injury might precede histopathological findings of allograft injury. We aimed to investigate if the type of induction therapy effect intragraft…
  • 2015 American Transplant Congress

    Predicting Obstructive Coronary Artery Disease in Asymptomatic Renal Patients Undergoing Renal Transplantation

    D.-A. Moutzouris, C. Baker, A. Malaweera, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Almost 50% of asymptomatic patients with End Stage Renal Disease (ESRD) are reported to have significant flow-limiting coronary artery disease (CAD). Our practice involves a…
  • 2015 American Transplant Congress

    Serum Uric Acid Is Associated With Hypertension in Kidney Donors

    S. Reule,1 R. Foley,1 A. Matas,2 H. Ibrahim.1

    1Department of Medicine, University of Minnesota, Minneapolis, MN; 2Department of Surgery, University of Minnesota, Minneapolis, MN.

    Introduction:Uric acid has been linked to the development of hypertension and possibly CKD. Moreover, some preliminary data suggests that lowering uric acid maybe associated with…
  • 2015 American Transplant Congress

    Results of ABO Incompatible Liver Transplantation Using a Simplified Protocol at a Single Institution

    J. Lee,1 J. Lee,1 J. Lee,2 M. Kim,1 M. Ju,1 G. Choi,1 J. Choi,1 S. Kim,1 D. Joo.1

    1Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Department of Surgery, CHA Bundang Medical Center, Bundang, Republic of Korea.

    BackgroundABO incompatible (ABOi) living donor liver transplantation (LDLT) has become a feasible option for patients with end-stage liver disease due to development of various desensitization…
  • 2015 American Transplant Congress

    Improved Renal Function Post-Liver Transplant With Earlier Everolimus Conversion

    S. Lin,1 M. Zimmerman,2 V. Lewis,1 S. Biggins,3 C. Ruller,4 I. Kam,4 T. Nydam.4

    1Pharmacy Dept, University of Colorado Hospital, Aurora; 2Division of Transplant Surgery, Medical College of Wisconsin, Wisconsin; 3Division of Gastroenterology/Hepatology, University of Colorado, Aurora; 4Division of Transplant Surgery, University of Colorado, Aurora.

    Calcineurin inhibitors (CNI) play an important role in preventing acute rejection (AR) post-liver transplant. Its long-term use is limited by development of nephrotoxicity. Optimal timing…
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