2015 American Transplant Congress
Live Donor Liver Transplantation With Older (>50years) Vs Younger (<50years) Donors: Does Age Matter?
Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Introduction: The risks of living donor liver transplantation (LDLT) with older donors remains controversial and many centers avoid using live donors ≥45 years of age.…2015 American Transplant Congress
miRNA-181 Promotes Graft Prolongation by Plasmacytoid Dendritic Cells By Increasing T Regulatory Cells and Decreasing B Cells as Revealed By Cytometry By Time-Of-Flight
1Surgery, Stanford University, Stanford, CA; 2Pediatrics, UCSF, San Francisco, CA.
Liver allografts are well tolerated and other solid organ allografts, when transplanted concurrently with livers, show improved outcomes. However, the mechanisms underlying “hepatic tolerance” have…2015 American Transplant Congress
Application of Second Generation Sequencing and AlloAntibody Screening to the Organ Transplantation Arena
Over the last two decades, over 300,000 solid organ transplantations have been performed in the USA alone. While there has been considerable progress with immunosuppression…2015 American Transplant Congress
Adverse Events of Maintenance Immunosuppression Following Kidney Transplantation Reported in Randomized Controlled Trials: A Systematic Review
Aim: To evaluate the completeness of reporting of adverse events in randomized controlled trials (RCTs) of maintenance immunosuppression in kidney transplantation.Background: Side effects of maintenance…2015 American Transplant Congress
Relationship Between Delayed Graft Function (DGF) Severity and Predicted DGF Risk
1Quark, Fremont; 2UCSF, SF; 3U of Barcelona, BCN, Spain.
Historically, dialysis required in the first post-transplant (TX) week has defined DGF. This incidence-based definition fails to discriminate between short versus long courses of dialysis…2015 American Transplant Congress
Organ Procurement Organization Level Changes in Liver Utilization After Share-35
Dept of Surgery, Johns Hopkins, Baltimore, MD.
The OPTN implemented Share-35 in June 2013 to increase regional sharing. Organ Procurement Organization (OPO)-level changes in utilization subsequent to Share-35 have not previously been…2015 American Transplant Congress
Effect of Intrapatient Variability and Mean Tacrolimus Levels in Renal Transplant Patients
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
IntroductionNonadherence (NA) to immunosuppressive medication and adherence to immunosuppressive protocols is a potent risk factor for rejection and graft loss, which can be both patient…2015 American Transplant Congress
B-Cell Tolerance to Donor Alloantigens
Pre-existing panel-reactive antibodies and development of donor-specific alloantibodies are known to play important roles in graft dysfunction and deterioration. Preventing and/or eliminating alloantibody responses would…2015 American Transplant Congress
Increased Precentage of Circulating CD16+ Monocytes Before Transplantation Are Associated With the Occurence of Acute Rejection
Introduction: Monocytes compose a neglected immune cell type in transplantation despite their contribution to antibody mediated rejection. We aimed to define the phenotypic and functional…2015 American Transplant Congress
Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…
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