ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Impact of Donor Alcohol Intake on Pancreatic Graft Survival

    R. Motallebzadeh,1 M. Drage,2 J. Olsburgh,2 C. Callaghan.2

    1Surgery, Cambridge University Hospital, Cambridge, United Kingdom; 2Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

    Introduction:Alcohol (EtOH) abuse can damage the pancreas, but outcomes of pancreas transplantation from donors with a high EtOH intake are poorly defined. The aim of…
  • 2015 American Transplant Congress

    Optimal Management of Distal Ureteric Stricture Following Renal Transplantation: A Systematic Review

    J. Kwong, D. Schiefer, G. Anas, J. Archambault, P. Luke, A. Sener.

    Urology, Western University, London, ON, Canada.

    Introduction And Objective: Ureteric stricture is the most common complication following renal transplantation, with an incidence of 3%. Of all ureteric strictures, 73% occur at…
  • 2015 American Transplant Congress

    Vaccine Responses in Combined Hematopoeitic Stem Cell-Kidney Transplant Recipients

    C. Feng,1 M. Ison,1 J. Galvin,1 S. Ildstad,2,3 D. Stare,1 J. Leventhal.1

    1Northwestern University, Chicago, IL; 2University of Louisville, Louisville, KY; 3Regenerex, LLC, Louisville, KY.

    Background: Vaccines remain one of the most effective methods of preventing infections following transplantation. Data suggests that vaccine responses are reduced in recipients of hematopoeitic…
  • 2015 American Transplant Congress

    Non-Invasive Imaging Modalities for Immune Monitoring of Vascularized Composite Allografts Using a Translational Large Animal Model

    G. Furtmüller,1 N. Crane,2 R. Luthra,2 E. Swanson,1 H.-T. Cheng,1 B. Oh,1 M. Fryer,1 E. Elster,2 W. Lee,1 G. Brandacher.1

    1Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; 2Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, MD.

    Purpose: To evaluate imaging modalities such as 3CCD and infrared (IR) technology as a means of non-invasive monitoring of graft acceptance and rejection in the…
  • 2015 American Transplant Congress

    Assessment of Viral-Specific Memory T Cell Responses and Infection Rates in HLA-Sensitized (HS) Kidney Transplant Patients (Tx Pts) Treated With Everolimus & Low-Dose Tacrolimus (Eve/Tac)

    S. Ge, J. Kahwaji, M. Chu, A. Karasyov, M. Castro, E. Hayrapetyan, D. Lovato, D. Thomas, J. Choi, S. Louie, A. Vo, S. Jordan, M. Toyoda.

    Transplant Immunology & Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles.

    Background: mTOR inhibitors stimulate viral-specific memory CD8+ T cell differentiation and increase viral clearance in infected Tx pts. HS pts desensitized (DES) with IVIG +…
  • 2015 American Transplant Congress

    Impact of Serial Change of Donor Specific Antibodies On the Graft Outcomes After Liver Transplantation

    D. Joo,1,2 J. Lee,3 J. Lee,1,2 J. Lee,1,2 S. Kim,4 D. Han,1,2 M. Ju,1,2 J. Choi,1,2 S. Kim,1,2 M. Kim.1,2

    1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; 2The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 3Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea; 4Department of Surgery, Wonju Yonsei University College of Medicine, Wonju, Korea.

    Introduction: This study aimed to investigate the acute rejection rate and graft function after liver transplantation according to pre-transplantation donor specific antibody (DSA) status and…
  • 2015 American Transplant Congress

    Activation of Th17 and Chronic Renal Allograft Rejection in Nonhuman Primates

    K. Hotta, A. Aoyama, P. Putheti, Y. Yamada, T. Ohura, R. Colvin, B. Cosimi, G. Benichou, T. Strom, T. Kawai.

    Transplant Center, Massachusetts General Hospital, Boston, MA.

    Background: We have previously reported successful induction of renal allograft tolerance in nonhuman primates (NHP) via a mixed chimerism approach. Although donor specific Th1 and…
  • 2015 American Transplant Congress

    Comprehensive Study of 3 Nomenclatures to Discriminate CD8 Subsets in Healthy Volunteers and in Kidney Transplant Recipients

    M. Yap,1,3 G. Tilly,1,3 M. Giral,1,2 S. Brouard,1,2 N. Degauque.1,2

    1UMR 1064, INSERM, Nantes, France; 2ITUN, CHU de Nantes, Nantes, France; 3Faculté de Médecine, Université de Nantes, Nantes, France.

    Objective. Historical classification to distinguish central memory (CM), naïve, effector memory (EM), and terminally-differentiated effector memory (TEMRA) CD8 T cells is based on CD45RA and…
  • 2015 American Transplant Congress

    Pyridoxine Deficiency After Solid Organ Transplant

    S. Van Arsdale,1 S. Yost,2 M. Meer,1 S. Schoentag,1 P. Kadambi,3 S. Habib.3

    1Department of Nutrition Services, University of Arizona Medical Center, Tucson, AZ; 2Department of Pharmacy, University of Arizona Medical Center, Tucson, AZ; 3Department of Medicine, University of Arizona College of Medicine, Tucson, AZ.

    BackgroundMicronutrient deficiencies have been discussed in the literature regarding post-transplant recipients. A proposed theory is that immunosuppressive medications or altered immune system cause pyridoxine deficiency…
  • 2015 American Transplant Congress

    Identification of Strategies to Facilitate Organ Donation Among African Americans

    J. Locke,1 H. Qu,2 R. Shewchuk,2 D. Segev,3 M. Martin.4

    1Surgery/Transplantation, University of Alabama at Birmingham, Birmingham, AL; 2Health Services Administration, University of Alabama at Birmingham, Birmingham, AL; 3Epidemiology, Johns Hopkins University, Baltimore, MD; 4Medicine/Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL.

    Background: African Americans (AA) are disproportionately affected by renal disease, yet few receive a kidney transplant. Surveys assessing attitude toward donation have demonstrated that AAs…
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