2015 American Transplant Congress
Renal Retransplantation in Simultaneous Pancreas Kidney Transplant Recipients
National Renal and Pancreatic Transplantation Unit, Beaumont Hospital, Dublin, Ireland.
Introduction:Simultaneous Pancreas Kidney Transplantation(SPK) is standard of care in selected patients with end stage renal failure secondary to diabetes mellitus. There is little literature examining…2015 American Transplant Congress
Renal Vein Elongation in Deceased Right Side Cadaveric Renal Grafts: Does It Increase the Risk of Thrombosis Or Hematoma Formation?
Urology, Federal University of Sao Paulo, Sao Paulo, Brazil.
INTRODUCTION:There is a perceived feeling that elongation of the renal vein in right sided kidney grafts facilitates the vascular anastomosis. On the other hand some…2015 American Transplant Congress
Donor CD47 Plays a Critical Role in the Control of Alloreactive T Cell Activation Following Hepatocyte Transplantation
Background: The interspecies incompatibility of CD47 is an important mechanism triggering rejection of cellular xenografts, including both hematopoietic and non-hematopoietic cells, by recipient macrophages. Our…2015 American Transplant Congress
MicroRNA-21 (miR-21) Expression in Hypothermic Machine Perfusate May Predict Early Outcomes in Kidney Transplantation
Introduction: Hypothermic machine perfusion is effective in improving outcomes from kidney transplantation and molecular analyses of hypothermic machine perfusate (HMP) have the potential to identify…2015 American Transplant Congress
Inflammatory Profiling of Hypothermic Machine Pumped Kidney Allografts
Medicine, University of California, San Diego, La Jolla, CA.
Background:Pulsatile Hypothermic Machine Perfusion (MP) offers an opportunity to define inflammatory molecules generated during renal ischemia. This study reports on allografts pumped at our OPO,…2015 American Transplant Congress
The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation
Intra abdominal pressure (IAP) is monitored in critically ill children because intra-abdominal hypertension (IAH) may be associated with renal dysfunction and adverse outcomes.We retrospectively examined…2015 American Transplant Congress
Lower Frequency of Regulatory T-Cells After Conversion from CNIs or mTORi to Belatacept in a Prospective Matched Controlled Study in Renal Allograft Recipients
Nephrology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Objective: Regulatory T-cells (Tregs) are considered to play a crucial role in maintaining control of immune response following renal transplantation (Tx). So far, only limited…2015 American Transplant Congress
CTLA4Ig Administered During T-Cell Priming Negates de novo Alloantibody Responses and Modulates Recall Antibody Production
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Arcadia, CA.
Background CTLA4Ig (Belatacept) is a novel anti-rejection therapy aimed at costimulatory blockade. Clinical data suggest that post-transplant alloantibody formation is also reduced in patients treated…2015 American Transplant Congress
Outcomes of Post-Kidney Transplant Leukemias
Medicine, University of Minnesota, Minneapolis, MN.
Background:Leukemias typically portend bad prognosis in the general population. The incidence and outcomes of post-kidney transplant leukemias (PKTL) have not been well studied as most…2015 American Transplant Congress
The Value of Surveillance Testing for De Novo Donor Specific Antibodies Following Renal Transplantation
1Medicine, SUNY at Buffalo/ECMC, Buffalo, NY; 2Surgery, SUNY at Buffalo/ECMC, Buffalo, NY.
The development of de novo donor specific antibodies (dnDSA) usually leads to a reduction in renal graft survival. The deleterious influence of dnDSA is most…
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