2013 American Transplant Congress
Impact of Tacrolimus (FK) Level on Evolution of Graft Function in the First Year after Kidney Transplant (KT) among Recipients with DGF: A Ten Year Retrospective Analysis
Univ of Florida, Gainesville, FL
Purpose: We aimed to analyze the impact of FK levels at selected time points after KT on the evolution of graft function (based on estimated…2013 American Transplant Congress
Predictors of Poor Outcomes Following Liver Transplantation in Patients with Hepatopulmonary Syndrome
Purpose. Orthotopic liver transplantation (OLT) is the only effective therapy for chronic liver disease patients with hepatopulmonary syndrome (HPS). Recent reports have documented improved long-term…2013 American Transplant Congress
Alemtuzumab Induction and Belatacept-Based Immunosuppression in Renal Transplant Recipients: Peripheral Dynamics of T and B Cell Populations with Potential Regulatory Signatures
Emory Transplant Center, Emory University, Atlanta, GA
Belatacept has been approved as a calcineurin inhibitor (CNI) replacement, but its optimal use has not been determined. We have performed a pilot trial using…2013 American Transplant Congress
Donor-Specific HLA Antibodies: Prediction of Pancreas Graft Outcome
Oxford Transplant Centre, Oxford, United Kingdom
Donor-specific HLA antibodies (DSA) are associated with poorer outcomes in kidney transplantation, however the role of DSA in pancreas transplantation is less well known. This…2013 American Transplant Congress
Regulatory T Cell Induction by Soluble Components of a Traditional Chinese Herb
Background: There is an ongoing need for development of novel immune suppressants, particularly those that enhance regulatory T cells (Treg). QMAD is a soluble fraction…2013 American Transplant Congress
Matrix Metalloproteinase-12 Is a Novel Mediator of Hepatic Ischemia-Reperfusion Injury
Surgery, University of California, Los Angeles, CA
Hepatic ischemia reperfusion injury (IRI), linked to leukocyte recruitment and subsequent release of cytokines and free radicals, remains a significant problem in organ transplantation. Leukocyte…2013 American Transplant Congress
Does Mannose-Binding Lectin Plasma Level Predict the Incidence of Cytomegalovirus Disease in Solid-Organ Transplant Recipients?
CHUV, Lausanne; , Basel; , Zuerich; , Bern; , Geneva; , St Gallen, Switzerland
Background: Mannose-binding lectin (MBL) is the initial component of the third complement activation pathway. Genetically-determined deficiency which is very prevalent has been implicated in the…2013 American Transplant Congress
Ex Vivo Expanded Human Regulatory T Cells Are Potent Suppressors but May Be Short-Lived
Translational Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA
Infusion of host derived ex vivo expanded regulatory T cells (eTregs) is an attractive therapeutic strategy for promotion of transplant tolerance. We report herein that…2013 American Transplant Congress
Evaluation of Non-Adherence in Patients Undergoing Dialysis, Pre- and Post-Kidney Transplantation: US Transplant Practice Patterns Survey
Introduction: We carried out a survey of US transplant centers to evaluate practice patterns in the assessment of non-adherence before and after kidney transplantation.Methods: An…2013 American Transplant Congress
Discrepancy between Biological Age and Calendar Age: A Large Histology Study in Implantation Biopsies, The
University Hospitals Leuven, Leuven, Belgium; Hasselt University, Hasselt, Belgium
BACKGROUNDThe histology and function of kidneys is thought to deteriorate with increasing age. Replicative senescence, associated with telomere shortening, plays an important role in this…
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