ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Anchoring Heparin to the Surface of Islet Improved Revascularization in Islet Transplantation

    X. Tian, Y. Li, H. Song, X. Ding, X. Feng, J. Hou, W. Xue, P. Tian

    The Department of Renal Transplantation, The First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China; The Department of Osteology, The Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China

    Objective: We all know that the inadequate blood supply is likely contributors to islet death in the immediate posttransplant period and may impair islet survival…
  • 2013 American Transplant Congress

    Dyslipidemia in the First Year after Renal Transplantation: Its Prevalence, Associated Clinical and Genomic Factors, and Graft Survival

    K. Numakura, S. Satoh, M. Saito, N. Komine, S. Akihama, T. Inoue, S. Narita, N. Tsuchiya, T. Habuchi

    Urology, Akita University Graduate School of Medicine, Akita, Japan; Renal Replacement Therapeutic Science, Akita University School of Medicine, Akita, Japan

    Introduction and Objective: Dyslipidemia is common among renal transplant recipients and may be a risk factor for cardiovascular disease and graft dysfunction. The present study…
  • 2013 American Transplant Congress

    Does the Abnormal Result of Implantation Renal Biopsy Affect the Donor Renal Function?

    W. Han, S. Yang, D. Joo, K. Huh, M. Kim, Y. Kim, S. Kim, K. Choi

    Urology, Yonsei University Health System, Urological Science Institute, Seoul, Republic of Korea; Surgery, The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction and Objectives. In this study, we focused on histological abnormalities which found in living kidney donor implantation biopsy (IB) and analyzed with renal function…
  • 2013 American Transplant Congress

    Bone Marrow-Derived Mesenchymal Stem Cells of Neonatal Mice Suppress Dendritic Cells Maturation and T Lymphocyte Proliferation

    X. Dai, X. Li, J. Ma, J. Wang, N. Gong

    Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Background: Mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be easily harvested in matured mice because of the low MSC frequency, contamination of hematopoietic cells…
  • 2013 American Transplant Congress

    Quantifying Improvement in Donor Travel Safety: Utilization of Centralized Procurement Facilities and outside Surgeon Organ Procurement

    S. Waits, K. Sheetz, W. Kanitz, M. Englesbe

    Department of Surgery, Division of Transplantation, University of Michigan, Ann Arbor, MI

    Intro: Air based organ procurement travel has been noted to be the dangerous. As a 5-year follow-up to the Michigan Donor Travel Forum, we sought…
  • 2013 American Transplant Congress

    Impact of Immunosenescence on Bone Marrow Transplantation (BMT) and Chimerism, The

    K. Hock, R. Oberhuper, Y. Lee, T. Wekerle, S. Tullius

    Department of Surgery, Medical University of Vienna, Vienna, Austria; Division of Transplant Surgery and Transplant Surgery Research Lab, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria

    Background:Tolerance induction through mixed chimerism holds promise for clinical translation but has only been investigated in young recipients. Changing demographics and an accumulation of older…
  • 2013 American Transplant Congress

    Adverse Events of Over-Immunosuppression Are Dependent on Tofacitinib Exposure in Kidney Transplant (KT) Patients

    S. Busque, F. Vincenti, H. Tedesco Silva, P. O'Connell, M. Tortorici, N. Lawendy, W. Wang, G. Chan

    Stanford Univ, Stanford; UCSF, San Francisco; Hosp do Rim e Hipertensao, Sao Paulo, Brazil; Westmead Hosp, Westmead, Australia; Pfizer, Groton

    Background: In a prior Phase 2b study in de novo KT pts, a CNI-free tofacitinib fixed-dose regimen achieved comparable rate of biopsy-proven acute rejection (BPAR),…
  • 2013 American Transplant Congress

    Donor CD4 T Cells Trigger Costimulation Blockade-Resistant Donor Bone Marrow Rejection through Bystander Activation Requiring Interleukin 6

    K. Hock, N. Pilat, U. Baranyi, B. Mahr, C. Klaus, M. Gattringer, T. Wekerle

    Division of Transplantation, Department of Surgery, Medical University of Vienna, Vienna, Austria

    Background:Donor T cells have pleiotropic effects in allogeneic bone marrow transplantation (BMT). Co-transplanting high doses of donor T cells with donor BM causes rejection of…
  • 2013 American Transplant Congress

    Mycophenolic Acid (MPA) Dosing: Effect on Efficacy to 4 Years after Kidney Transplantation in the Mycophenolic Acid Observational Renal Transplant (MORE) Study

    L. Chan, F. Shihab, O. Pankewycz, C. Doria, A. Wiland, K. McCague, A. Langone

    University of Colorado School of Medicine, Aurora, CO; University of Utah School of Medicine, Salt Lake City, UT; Erie County Medical Center, Buffalo, NY; Thomas Jefferson University Hospital, Philadelphia, PA; Novartis Pharmaceuticals Corporation, East Hanover, NJ; Vanderbilt University Medical Center, Nashville, TN

    Maintaining adequate MPA dose may be important to optimize efficacy after kidney transplantation, but prospective long-term data are rare.Methods. MORE was a prospective, observational study…
  • 2013 American Transplant Congress

    Epigenetic Analysis of the TSDR of FOXP3 Demonstrates That Natural Treg Infiltrate the Cardiac Allograft Already before an Acute Rejection Episode

    K. Boer, A. Peeters, A. Maat, K. Caliskan, A. Balk, W. Weimar, C. Baan

    Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; Thoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands

    IntroductionTwo subtypes of FOXP3+ regulatory T cells (Treg) have been identified. Natural (n) Treg originate in the thymus, while antigen specific induced (i) Treg are…
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